Dopamine News and Research

Latest Dopamine News and Research

Chronic lack of sleep, irregular sleep-wake cycles may increase risk of Parkinson's disease

Chronic lack of sleep and irregular sleep-wake cycles may be risk factors of Parkinson's disease, new work by researchers at the Lewis Katz School of Medicine at Temple University suggests. In an animal model, the researchers show that disturbances in circadian rhythm that exist before Parkinson's onset dramatically worsen motor and learning deficits brought on by the disease.

5 Apr 2016

Electrical stimulation of deep brain structures to ease chronic pain

Abuse of prescription opioid medicines used to treat chronic pain has reached epidemic proportions, so much that the White House has announced new efforts to combat addiction and prevent the thousands of overdose-related deaths reported in the U.S. each year.

5 Apr 2016

Sweet foods invoke different brain circuits

Different brain circuits are invoked by the pleasure we derive from eating sweet foods and the calories they supply.

25 Mar 2016

Common parasitic infection linked to intermittent explosive disorder

In recent years, a common parasitic infection - as many as a third of the world's population may have it - has been linked to a range of psychiatric disorders, including schizophrenia and bipolar disorder, as well as behavioral dysregulation such as suicide attempts and car accidents.

24 Mar 2016

MU researchers use MRI to study effects of Phenylketonuria

All children are screened for a host of conditions at birth, such as Phenylketonuria (PKU), a genetic disorder that is passed by mutated genes from both parents to their offspring. PKU is rare, only affecting one in every 10,000 children in the U.S.; therefore, it is seldom studied.

23 Mar 2016

Warning of increased mortality risk for PD patients taking antipsychotics

Researchers have found a more than twofold increase in the risk of death among patients with Parkinson's disease who take antipsychotics, particularly typical antipsychotics.

23 Mar 2016

Antipsychotic drugs may do significantly more harm to Parkinson's disease patients

At least half of Parkinson's disease patients experience psychosis at some point during the course of their illness, and physicians commonly prescribe antipsychotic drugs, such as quetiapine, to treat the condition. However, a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, the University of Michigan Medical School, and the Philadelphia and Ann Arbor Veterans Affairs Medical Centers and suggests that these drugs may do significantly more harm in a subset of patients.

21 Mar 2016

New scaffold technology could someday help treat Parkinson's disease, other brain-related conditions

Scientists at Rutgers and Stanford universities have created a new technology that could someday help treat Parkinson's disease and other devastating brain-related conditions that affect millions of people.

18 Mar 2016

New 3D micro-scaffold technology promotes reprogramming of stem cells into neurons

National Institutes of Health-funded scientists have developed a 3D micro-scaffold technology that promotes reprogramming of stem cells into neurons, and supports growth of neuronal connections capable of transmitting electrical signals.

18 Mar 2016

Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

Orexigen Therapeutics, Inc. today announced Valeant Pharmaceuticals International, Inc. will commercialize Mysimba (naltrexone HCl / bupropion HCl prolonged release) in Central and Eastern Europe.

15 Mar 2016

Scientists discover brain mechanisms that separate food consumption from cravings

Researchers investigating eating disorders often study chemical and neurological functions in the brain to discover clues to overeating. Understanding non-homeostatic eating -- or eating that is driven more by palatability, habit and food cues -- and how it works in the brain may help neuroscientists determine how to control cravings, maintain healthier weights and promote healthier lifestyles. Scientists at the University of Missouri recently discovered the chemical circuits and mechanisms in the brain that separate food consumption from cravings. Knowing more about these mechanisms could help researchers develop drugs that reduce overeating.

9 Mar 2016

Geneticists explore evolution of musical aptitude

Geneticists at the University of Helsinki and the National University of Singapore have teamed up to explore the evolution of musical aptitude in the first-ever empirical study of the evolution of music.

3 Mar 2016

Polyunsaturated lipids can alter binding rate of two receptors involved in Parkinson's and Alzheimer's

A study published in the prestigious journal Scientific Reports from the Nature group demonstrates, for the first time and using computational tools, that polyunsaturated lipids can alter the binding rate of two types of receivers involved in certain nervous system diseases.

2 Mar 2016

CAMH, Impel NeuroPharma partner to advance novel treatment to alleviate depression

The Centre for Addiction and Mental Health and Impel NeuroPharma have signed a licensing agreement to advance a new neuropeptide-based therapeutic approach shown to be effective in treating depression.

1 Mar 2016

Scientists develop new optical technique to observe neurotransmitter activity of individual synapses

Columbia University scientists have developed a new optical technique to study how information is transmitted in the brains of mice. Using this method, they found that only a small portion of synapses -- the connections between cells that control brain activity--may be active at any given time.

26 Feb 2016

Pitt experts lead gene therapy clinical trial in Parkinson's disease patients

Experts at the University of Pittsburgh School of Medicine are leading the second arm of a clinical trial using gene therapy to relieve the symptoms of tremor and mobility impairment in patients with Parkinson's disease.

23 Feb 2016

Regrowing dopaminergic neurons may lead to new therapy for Parkinson's disease

While scientists are unsure of the molecular causes of Parkinson's Disease, they do know the disorder's tremors and other motor dysfunctions are linked to a loss of dopaminergic neurons located in the substantia nigra, a structure in the midbrain.

16 Feb 2016

Researchers report first-ever link between noradrenergic neurons and vulnerability to depression

The team of Bruno Giros, a researcher at the Douglas Mental Health University Institute and professor of psychiatry at McGill University, reports the first-ever connection between noradrenergic neurons and vulnerability to depression. Published in the journal Nature Neuroscience, this breakthrough paves the way for new depression treatments that target the adrenergic system.

15 Feb 2016

Human brains prioritize and reinforce high-reward memories

Why do we remember some events, places and things, but not others? Our brains prioritize rewarding memories over others, and reinforce them by replaying them when we are at rest, according to new research from the University of California, Davis, Center for Neuroscience, published Feb. 11 in the journal Neuron.

15 Feb 2016

Wayne State inks exclusive license agreement with TRImaran Pharma for novel class of drugs

Wayne State University recently entered into an exclusive license agreement with TRImaran Pharma Inc. for a class of novel drugs developed at Wayne State University that aims to offer hope in the treatment of post-traumatic stress disorders (PTSD), depression, ADHD and other neurological disorders.

9 Feb 2016

Dopamine News and Research

Latest Dopamine News and Research

Chronic lack of sleep, irregular sleep-wake cycles may increase risk of Parkinson's disease

Electrical stimulation of deep brain structures to ease chronic pain

Sweet foods invoke different brain circuits

Common parasitic infection linked to intermittent explosive disorder

MU researchers use MRI to study effects of Phenylketonuria

Warning of increased mortality risk for PD patients taking antipsychotics

Antipsychotic drugs may do significantly more harm to Parkinson's disease patients

New scaffold technology could someday help treat Parkinson's disease, other brain-related conditions

New 3D micro-scaffold technology promotes reprogramming of stem cells into neurons

Orexigen Therapeutics, Valeant Pharmaceuticals sign distribution agreement for Mysimba

Scientists discover brain mechanisms that separate food consumption from cravings

Geneticists explore evolution of musical aptitude

Polyunsaturated lipids can alter binding rate of two receptors involved in Parkinson's and Alzheimer's

CAMH, Impel NeuroPharma partner to advance novel treatment to alleviate depression

Scientists develop new optical technique to observe neurotransmitter activity of individual synapses

Pitt experts lead gene therapy clinical trial in Parkinson's disease patients

Regrowing dopaminergic neurons may lead to new therapy for Parkinson's disease

Researchers report first-ever link between noradrenergic neurons and vulnerability to depression

Human brains prioritize and reinforce high-reward memories

Wayne State inks exclusive license agreement with TRImaran Pharma for novel class of drugs

Quality, Patient Safety and Innovation Manager at Elsevier

How Bruker worked with the University of Manchester on mapping the dynamics of complex protein

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Dopamine News and Research

Latest Dopamine News and Research

Quality, Patient Safety and Innovation Manager at Elsevier

How Bruker worked with the University of Manchester on mapping the dynamics of complex protein

Real-time Raman monitoring for pharmaceutical hot melt extrusion

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