Epigenetics News and Research

Latest Epigenetics News and Research

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Drug resistance is a major obstacle to effective treatment for patients with cancer and leukemia. Epigenetic modifying drugs have been proven effective for some patients with hematologic malignancies, such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).

23 Mar 2018

Study identifies gene that influences risk of obesity in adulthood

The importance of good nutrition in the early development of children has been recognized for many decades. Nutritional experiences in early life can have profound and long-lasting effects on body weight in later life.

13 Mar 2018

Study findings establish basis for epigenetic link between aging and Alzheimer's disease

Although certain genetic variants increase the risk of Alzheimer's disease (AD), age is the strongest known risk factor. But the way in which molecular processes of aging predispose people to AD, or become impaired in AD remains a mystery.

6 Mar 2018

New compounds targeting epigenetics show promise in lymphoma patients

New compounds targeting epigenetics have shown remarkable early activity in patients with lymphoma, according to data presented at the TAT (Targeted Anticancer Therapies) International Congress 2018 in Paris, France.

5 Mar 2018

Scientists explore factors that most affect our immune system

Why do we respond differently to infections or vaccines? Why are some people allergic to pollen? These are still unanswered questions in biological and medical science.

28 Feb 2018

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Celgene Corporation today announced that it has received a Refusal to File letter from the United States Food and Drug Administration regarding its New Drug Application for ozanimod in development for the treatment of patients with relapsing forms of multiple sclerosis.

27 Feb 2018

Asthmatics have lower degree of DNA methylation in certain immune cells

Children with asthma have epigenetic DNA changes in certain cells of their immune system, a major international study involving researchers at Karolinska Institutet shows. The finding, which is presented in The Lancet Respiratory Medicine, can one day lead to improved diagnostics and treatment.

23 Feb 2018

Penn study sheds new light on immune cell identity

Almost all cells in the human body have identical DNA sequences, yet there are 200-plus cell types with different sizes, shapes, and chemical compositions. Determining what parts of the genome are read to make protein and which are silenced is orchestrated by proteins called transcription factors.

21 Feb 2018

Cutting either carbs or fats shaves off excess weight in the same proportion, study reveals

New evidence from a study at the Stanford University School of Medicine might dismay those who have chosen sides in the low-fat versus low-carb diet debate.

21 Feb 2018

Key protein involved in epigenetic regulation of gene expression guides skin cell renewal

Approximately once a month, our skin completely renews itself. If this highly coordinated process goes awry, it can lead to a variety of skin diseases, ranging from skin cancer to psoriasis.

19 Feb 2018

Father's stress affects the brain development of offspring, mice study shows

New research in mice has found that a father's stress affects the brain development of his offspring. This stress changes the father's sperm, which can then alter the brain development of the child. This new research provides a much better understanding of the key role that fathers play in the brain development of offspring.

19 Feb 2018

Researchers uncover new details about function of enigmatic protein

In a recent study, a research group at MedUni Vienna has published further details about the function of an enigmatic protein. The biological necessity of this protein, which can chemically alter certain building blocks of the genetic information, has been debated for quite a while.

14 Feb 2018

Scientists use novel epigenetic-centered techniques to inhibit cancer metastases

In one of the first successes of its kind, researchers from Case Western Reserve University School of Medicine and six other institutions have inhibited the spreading of cancer cells from one part of the body to another.

12 Feb 2018

Researchers propose new regulation mechanism linked to action of SirT6 on chromatin

Researchers from the Epigenetics and Cancer Biology Program of the Bellvitge Biomedical Research Institute, led by Dr. Àlex Vaquero, have proposed a new regulation mechanism of the NF-κB pathway, which is associated with accelerated cellular aging, based on the analysis of the function of the SirT6 protein.

19 Jan 2018

Sex steroid hormone fluctuations may have direct effects on eye physiology and AMD

Gender-based differences may influence several ocular conditions, suggesting that fluctuations in sex steroid homeostasis may have direct effects on eye physiology and the pathogenesis of conditions like Age-Related Macular Degeneration.

18 Jan 2018

Researchers discover why exercise is good and high blood pressure is bad for the heart

When the heart is put under stress during exercise, it is considered healthy. Yet stress due to high blood pressure is bad for the heart. Why? And is this always the case? Researchers of the German Centre for Cardiovascular Research and of Heidelberg University Hospital have obtained new findings which indicate that a previously undetected signal pathway causes or protects from heart failure - depending on the type of stress.

9 Jan 2018

Identical twins share additional level of molecular similarity

An international group of researchers has discovered a new phenomenon that occurs in identical twins: independent of their identical genes, they share an additional level of molecular similarity that influences their biological characteristics.

9 Jan 2018

Research sheds light on role of epigenetics in placing egg cells into stasis

Keeping egg cells in stasis during childhood is a key part of female fertility. New research published today (1st January) in Nature Structural and Molecular Biology sheds some light on the role of epigenetics in placing egg cells into stasis.

2 Jan 2018

Epigenetics: A New Tool for Forensic Detectives

Developing analytical methods can help the triers of fact, judges and juries, better understand the events surrounding the circumstances of a crime. In forensic analysis, we are talking about determining the identity of unknown individuals through DNA and using DNA and other chemical signatures to determine and clarify the circumstances of the crime.

From Pittcon 20 Dec 2017

Scientists develop test to predict treatment outcomes in patients with childhood leukemia

UC San Francisco physician-scientists have developed a test that can predict how patients with juvenile myelomonocytic leukemia (JMML) will respond to treatment, and may also be able to identify patients who are likely to recover spontaneously with little to no treatment.

19 Dec 2017

Epigenetics News and Research

Latest Epigenetics News and Research

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Study identifies gene that influences risk of obesity in adulthood

Study findings establish basis for epigenetic link between aging and Alzheimer's disease

New compounds targeting epigenetics show promise in lymphoma patients

Scientists explore factors that most affect our immune system

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Asthmatics have lower degree of DNA methylation in certain immune cells

Penn study sheds new light on immune cell identity

Cutting either carbs or fats shaves off excess weight in the same proportion, study reveals

Key protein involved in epigenetic regulation of gene expression guides skin cell renewal

Father's stress affects the brain development of offspring, mice study shows

Researchers uncover new details about function of enigmatic protein

Scientists use novel epigenetic-centered techniques to inhibit cancer metastases

Researchers propose new regulation mechanism linked to action of SirT6 on chromatin

Sex steroid hormone fluctuations may have direct effects on eye physiology and AMD

Researchers discover why exercise is good and high blood pressure is bad for the heart

Identical twins share additional level of molecular similarity

Research sheds light on role of epigenetics in placing egg cells into stasis

Epigenetics: A New Tool for Forensic Detectives

Scientists develop test to predict treatment outcomes in patients with childhood leukemia

eBook: A guide to RNA sequencing eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Epigenetics News and Research

Latest Epigenetics News and Research

eBook: A guide to RNA sequencing eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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