Epigenetics News and Research

Latest Epigenetics News and Research

New drug reduces symptoms of Rett syndrome in preclinical models

A new article published in the Cell Reports describes how a new drug is able to reduce the symptoms and activate the dormant neurons characteristic of Rett Syndrome in preclinical models.

14 May 2018

Scientists uncover genome variation linked to increased risk of developing Alzheimer's

An article published in Nature Medicine with the collaboration of the research group of Dr. Manel Esteller, director of the Epigenetics and Cancer Biology Program of the Bellvitge Biomedical Research Institute, ICREA Researcher and Professor of Genetics of the University of Barcelona, and Drs. Dave Monk and Isidre Ferrer, from the same center, shows that the inheritance of small changes in DNA alters the expression of the PM20D1 gene and is associated with an increased risk of developing Alzheimer's disease.

14 May 2018

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center.

8 May 2018

Plants provide a new avenue in curbing tumor growth

Plants have provided a new avenue in curbing tumor growth. On this occasion, it doesn't involve miracle species or the like, but rather the results obtained by the University of Cordoba BIO301 research team called "Epigenetics and DNA Repair."

27 Apr 2018

Drawbacks and benefits of using saliva for epigenetic studies

Biomarkers in saliva identify changes that impact the body, according to research published in Current Genomics. This important paper details the drawbacks and benefits of using saliva as a tissue sample for the study of epigenetic changes affected by experiences.

20 Apr 2018

Long-term exposure to cold temperatures reduces diabetes and obesity, shows study

A new study in fat cells has revealed a molecular mechanism that controls how lifestyle choices and the external environment affect gene expression.

19 Apr 2018

Researcher explores how children develop immunity to malaria as they grow older

Across the world, over 200 million cases of malaria and nearly 500,000 deaths from the disease occur annually--more than 90 percent of which happen in Africa. Children in Africa can be diagnosed with malaria two or three times a year, a rate that decreases as they become older and develop immunity. But the way children generate and maintain this immunity remains a mystery.

11 Apr 2018

Scientists find new molecular target to treat idiopathic pulmonary fibrosis

Scientists searching for a therapy to stop the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF), found a new molecular target that slows or stops the illness in preclinical laboratory tests.

10 Apr 2018

Insilico to present recent advances in AI for aging biomarkers and age management research

Insilico Medicine, a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for drug discovery, biomarker development and aging research, is pleased to announce the presentation of its Director of Drug Discovery, Dr. Ivan Ozerov, at the 24th Clinical Applications for Age Management Medicine Conference, April 27, 2018, organized by Age Management Medicine Group.

6 Apr 2018

Johns Hopkins scientist calls for more integration of epigenetics and genetics research

In a review article published April 5 in the New England Journal of Medicine, scientist Andrew Feinberg, M.D., calls for more integration between two fields of DNA-based research: genetics and epigenetics.

6 Apr 2018

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Drug resistance is a major obstacle to effective treatment for patients with cancer and leukemia. Epigenetic modifying drugs have been proven effective for some patients with hematologic malignancies, such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).

23 Mar 2018

Study identifies gene that influences risk of obesity in adulthood

The importance of good nutrition in the early development of children has been recognized for many decades. Nutritional experiences in early life can have profound and long-lasting effects on body weight in later life.

13 Mar 2018

Study findings establish basis for epigenetic link between aging and Alzheimer's disease

Although certain genetic variants increase the risk of Alzheimer's disease (AD), age is the strongest known risk factor. But the way in which molecular processes of aging predispose people to AD, or become impaired in AD remains a mystery.

6 Mar 2018

New compounds targeting epigenetics show promise in lymphoma patients

New compounds targeting epigenetics have shown remarkable early activity in patients with lymphoma, according to data presented at the TAT (Targeted Anticancer Therapies) International Congress 2018 in Paris, France.

5 Mar 2018

Scientists explore factors that most affect our immune system

Why do we respond differently to infections or vaccines? Why are some people allergic to pollen? These are still unanswered questions in biological and medical science.

28 Feb 2018

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Celgene Corporation today announced that it has received a Refusal to File letter from the United States Food and Drug Administration regarding its New Drug Application for ozanimod in development for the treatment of patients with relapsing forms of multiple sclerosis.

27 Feb 2018

Asthmatics have lower degree of DNA methylation in certain immune cells

Children with asthma have epigenetic DNA changes in certain cells of their immune system, a major international study involving researchers at Karolinska Institutet shows. The finding, which is presented in The Lancet Respiratory Medicine, can one day lead to improved diagnostics and treatment.

23 Feb 2018

Penn study sheds new light on immune cell identity

Almost all cells in the human body have identical DNA sequences, yet there are 200-plus cell types with different sizes, shapes, and chemical compositions. Determining what parts of the genome are read to make protein and which are silenced is orchestrated by proteins called transcription factors.

21 Feb 2018

Cutting either carbs or fats shaves off excess weight in the same proportion, study reveals

New evidence from a study at the Stanford University School of Medicine might dismay those who have chosen sides in the low-fat versus low-carb diet debate.

21 Feb 2018

Key protein involved in epigenetic regulation of gene expression guides skin cell renewal

Approximately once a month, our skin completely renews itself. If this highly coordinated process goes awry, it can lead to a variety of skin diseases, ranging from skin cancer to psoriasis.

19 Feb 2018

Epigenetics News and Research

Latest Epigenetics News and Research

New drug reduces symptoms of Rett syndrome in preclinical models

Scientists uncover genome variation linked to increased risk of developing Alzheimer's

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Plants provide a new avenue in curbing tumor growth

Drawbacks and benefits of using saliva for epigenetic studies

Long-term exposure to cold temperatures reduces diabetes and obesity, shows study

Researcher explores how children develop immunity to malaria as they grow older

Scientists find new molecular target to treat idiopathic pulmonary fibrosis

Insilico to present recent advances in AI for aging biomarkers and age management research

Johns Hopkins scientist calls for more integration of epigenetics and genetics research

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Study identifies gene that influences risk of obesity in adulthood

Study findings establish basis for epigenetic link between aging and Alzheimer's disease

New compounds targeting epigenetics show promise in lymphoma patients

Scientists explore factors that most affect our immune system

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Asthmatics have lower degree of DNA methylation in certain immune cells

Penn study sheds new light on immune cell identity

Cutting either carbs or fats shaves off excess weight in the same proportion, study reveals

Key protein involved in epigenetic regulation of gene expression guides skin cell renewal

eBook: A guide to RNA sequencing eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

Epigenetics News and Research

Latest Epigenetics News and Research

eBook: A guide to RNA sequencing eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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