Epigenetics News and Research

Latest Epigenetics News and Research

CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets.

19 Jan 2017

Study finds link between obesity-related disease and epigenetic modifications

Obesity has been linked to "letter" changes at many different sites in the genome, yet these differences do not fully explain the variation in people's body mass index (BMI) or why some overweight people develop health complications while others don't.

18 Jan 2017

Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

17 Jan 2017

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Metastatic pancreatic cancer -- cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths -- changes its metabolism and is "reprogrammed" for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

16 Jan 2017

Harvard scientists discuss promise and peril of emerging IVG technique

In vitro fertilization has transformed reproductive medicine and sparked a number of therapeutic and diagnostic breakthroughs.

12 Jan 2017

Epigenetic modification may be cause of adult throat cancers linked to alcohol, tobacco use

A team of researchers at the Research Institute of the McGill University Health Centre has found an epigenetic modification that might be the cause of 15% of adult cancers of the throat linked to alcohol and tobacco use.

12 Jan 2017

Antioxidant may prevent development of NAFLD in offspring of obese mothers

In new research published online in The FASEB Journal, scientists show that the antioxidant pyrroloquinoline quinone may prevent the development of nonalcoholic fatty liver disease in offspring.

10 Jan 2017

Epigenetic changes favor development of fatty liver in humans and mice

Mice with a strong tendency to obesity already exhibit epigenetic changes at six weeks of age, inducing the liver to amplify its production of the enzyme DPP4 and release it into the circulation. Over the long term, this favors the development of a fatty liver.

9 Jan 2017

Second-hand smoke exposures before conception affect fetal brain development

Exposure to second-hand tobacco smoke -- even before conception -- appears to have a lingering impact that can later impair the brain development of a fetus, researchers at Duke Health report.

5 Jan 2017

Global new partnership awarded 15 million euro to find better treatments for Multiple Sclerosis

A large global new partnership called 'MultipleMS', coordinated by Karolinska Institute in Sweden, has been awarded 15 million euro from the European Commission in the Horizon2020 program to find novel and better treatments for Multiple Sclerosis (MS).

5 Jan 2017

NIH researchers identify molecular mechanisms that may underlie woman's susceptibility to PMDD

National Institutes of Health researchers have discovered molecular mechanisms that may underlie a woman's susceptibility to disabling irritability, sadness, and anxiety in the days leading up to her menstrual period.

3 Jan 2017

Scientists report new molecular mechanism that could be cause of autoimmune diseases

Scientists at the Immunology Frontier Research Center (IFReC), Osaka University, Japan, report a new molecular mechanism that could explain the cause of some autoimmune diseases.

27 Dec 2016

Whitehead Institute researchers identify mechanism underlying cancer drug-resistance

The use of proteasome inhibitors to treat cancer has been greatly limited by the ability of cancer cells to develop resistance to these drugs.

27 Dec 2016

New discovery could lead to effective drugs to prevent excessive lymphatic growth in cancer

Cancer cells spread to other sites in the body through promoting the growth of new 'roads' to travel on.

27 Dec 2016

High BMI leads to epigenetic changes, study shows

The extra pounds you gain during the holidays will not only show up on your hips but will also affect your DNA.

22 Dec 2016

Research sheds new light on key drivers of cancer metastasis

Latest research from New Zealand's University of Otago is shedding new light on why and how cancer cells spread from primary tumours to other parts of the body. This phenomenon - known as metastasis - causes about 90 per cent of all cancer deaths.

21 Dec 2016

Low-carbohydrate diet may help reverse inherited intellectual disability linked to Kabuki syndrome

Experimenting on mice with a genetic change similar to that found in people with a rare inherited disease called Kabuki syndrome, Johns Hopkins scientists report that a very low-carbohydrate diet can "open up" DNA and improve mental function.

20 Dec 2016

U-M awarded NIH grant to investigate molecular changes that occur during and after physical activity

The University of Michigan was recently awarded $8.2 million from the National Institutes of Health to investigate the molecular changes that occur during and after physical activity.

16 Dec 2016

Researchers find new insights into silencing of X-chromosomes in human embryos

Researchers have discovered new insights into how one of the two X-chromosomes is silenced during the development of female human embryos and also in lab-grown stem cells.

16 Dec 2016

Viral infection during pregnancy affects maternal care and can trigger depression in offspring

A viral infection in a pregnant woman not only affects her subsequent ability to provide maternal care but can also trigger depression in her offspring, which can then even extend into the next generation as a result of changes to genetic mechanisms in the brain.

15 Dec 2016

Epigenetics News and Research

Latest Epigenetics News and Research

CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Study finds link between obesity-related disease and epigenetic modifications

Epigenetic changes drive successful metastases of pancreatic cancer cells

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Harvard scientists discuss promise and peril of emerging IVG technique

Epigenetic modification may be cause of adult throat cancers linked to alcohol, tobacco use

Antioxidant may prevent development of NAFLD in offspring of obese mothers

Epigenetic changes favor development of fatty liver in humans and mice

Second-hand smoke exposures before conception affect fetal brain development

Global new partnership awarded 15 million euro to find better treatments for Multiple Sclerosis

NIH researchers identify molecular mechanisms that may underlie woman's susceptibility to PMDD

Scientists report new molecular mechanism that could be cause of autoimmune diseases

Whitehead Institute researchers identify mechanism underlying cancer drug-resistance

New discovery could lead to effective drugs to prevent excessive lymphatic growth in cancer

High BMI leads to epigenetic changes, study shows

Research sheds new light on key drivers of cancer metastasis

Low-carbohydrate diet may help reverse inherited intellectual disability linked to Kabuki syndrome

U-M awarded NIH grant to investigate molecular changes that occur during and after physical activity

Researchers find new insights into silencing of X-chromosomes in human embryos

Viral infection during pregnancy affects maternal care and can trigger depression in offspring

Genetics & Genomics - Second Edition eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Epigenetics News and Research

Latest Epigenetics News and Research

Genetics & Genomics - Second Edition eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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