Epigenetics News and Research

Latest Epigenetics News and Research

Methylation status of ten positions in genome correlates with all-cause mortality

Various chemical modifications in the genome determine whether genes are read or deactivated. Methyl labels in the DNA play a key role in this "epigenetic" regulation of gene activity.

20 Mar 2017

First physiological test opens door to early diagnosis of autism

An algorithm based on levels of metabolites found in a blood sample can accurately predict whether a child is on the Autism spectrum of disorder (ASD), based upon a recent study.

16 Mar 2017

Low levels of allopregnanolone hormone may predict risk of postpartum depression

In a small-scale study of women with previously diagnosed mood disorders, Johns Hopkins researchers report that lower levels of the hormone allopregnanolone in the second trimester of pregnancy were associated with an increased chance of developing postpartum depression in women already known to be at risk for the disorder.

14 Mar 2017

York researchers move closer to finding new treatments for chronic bladder diseases

Using human cells, they have mapped how different proteins bind along the DNA to control which genes are active during barrier formation.

14 Mar 2017

Heroin use linked to epigenetic alterations in the brain

The past few years have seen an explosion of heroin abuse and deaths from opiate overdose. But little is known about the molecular underpinnings of heroin addiction.

14 Mar 2017

B vitamins may play critical role in reducing epigenetic effects of air pollution

A new study by researchers at Columbia University's Mailman School of Public Health showed that B vitamins may play a critical role in reducing the impact of air pollution on the epigenome, further demonstrating the epigenetic effects of air pollution on health.

14 Mar 2017

Study traces molecular roots of uterine carcinosarcoma using genomic, proteomic analyses

Researchers have charted the complex molecular biology of uterine carcinosarcoma, a rare and aggressive gynecologic cancer, according to a study published on March 13 in Cancer Cell.

13 Mar 2017

Chronic exposure to childhood bullying may have lifelong health effects

Being bullied during childhood might have lifelong health effects related to chronic stress exposure--including an increased risk for heart disease and diabetes in adulthood, according to a research review in the March/April issue of the Harvard Review of Psychiatry.

10 Mar 2017

Factors contributing to childhood adiposity begin before birth, study shows

A new article, published in the journal BMC Medicine, reports the largest epigenome-wide association study to date that provides evidence that factors contributing to childhood adiposity (level of body fat) begin before birth and are influenced by mother’s lifestyle, and fetal genetic and epigenetic factors.

9 Mar 2017

SETD8 enzyme protects against cellular senescence, research reveals

An enzyme that blocks cellular senescence and its mechanisms has been discovered by a research team from Kumamoto University, Japan. They found that a reduction of the enzyme SETD8, which regulates cell proliferation and gene function, results in the promotion of cell aging features.

8 Mar 2017

Research findings could guide development of potent combination therapies for leukemia

New findings from Rockefeller University researchers could guide the development of potent combination therapies that deliver more effective and durable treatment of leukemia.

7 Mar 2017

Clinical study seeks to examine new combination therapy for treating AML patients

A pair of drugs that may be a one-two punch needed to help combat acute myeloid leukemia (AML), an aggressive blood cancer that kills nearly three-fourths of patients within five years of diagnosis, is the focus of a new multi-center clinical trial that will enroll patients at three sites across the U.S.

7 Mar 2017

Study establishes ENL protein as potential drug target for acute myeloid leukemia

Anyone who uses an employee badge to enter a building may understand how a protein called ENL opens new possibilities for treating acute myeloid leukemia (AML), a fast-growing cancer of bone marrow and blood cells and the second most common type of leukemia in children and adults.

2 Mar 2017

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Researchers at Monash University and Peter MacCallum Cancer Centre have identified for the first time how a new class of epigenetic drug engages with the immune system to kill off cancer cells, offering powerful new pathways for enhanced blood cancer therapies.

1 Mar 2017

Researchers identify genetic variants that may contribute to schizophrenia

New research has identified sections of DNA associated with altered regulation of gene expression underlying schizophrenia.

27 Feb 2017

Study shows how old blood stem cells can be rejuvenated

When we are young, our blood stem cells produce an even and well-balanced number of red and white blood cells according to need. As we age, however, the capacity of the blood stem cells to produce the number of blood cells we need declines.

24 Feb 2017

Computational software that evaluates DNA samples may help in diagnosis, treatment of cancer

A research team from the United States and Canada has developed and successfully tested new computational software that determines whether a human DNA sample includes an epigenetic add-on linked to cancer and other adverse health conditions.

From Oxford Nanopore Technologies 24 Feb 2017

Children exposed to early deprivation could experience mental health problems in early adulthood

Experiencing severe deprivation and neglect in childhood can have a lasting psychological impact into early adulthood, according to a unique study which has followed the mental health of a group of children adopted from Romanian institutions to UK families in the 1990s.

24 Feb 2017

Cocaine use by fathers may negatively impact cognitive development in male offspring

Fathers who use cocaine at the time of conceiving a child may be putting their sons at risk of learning disabilities and memory loss.

24 Feb 2017

Lack of methyl groups in gene body may lead to emergence of cancer

Every cell in our body contains the complete DNA library. So-called methyl groups regulate that in body tissues only the genetic information is expressed that is indeed needed in this tissue.

23 Feb 2017

Epigenetics News and Research

Latest Epigenetics News and Research

Methylation status of ten positions in genome correlates with all-cause mortality

First physiological test opens door to early diagnosis of autism

Low levels of allopregnanolone hormone may predict risk of postpartum depression

York researchers move closer to finding new treatments for chronic bladder diseases

Heroin use linked to epigenetic alterations in the brain

B vitamins may play critical role in reducing epigenetic effects of air pollution

Study traces molecular roots of uterine carcinosarcoma using genomic, proteomic analyses

Chronic exposure to childhood bullying may have lifelong health effects

Factors contributing to childhood adiposity begin before birth, study shows

SETD8 enzyme protects against cellular senescence, research reveals

Research findings could guide development of potent combination therapies for leukemia

Clinical study seeks to examine new combination therapy for treating AML patients

Study establishes ENL protein as potential drug target for acute myeloid leukemia

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Researchers identify genetic variants that may contribute to schizophrenia

Study shows how old blood stem cells can be rejuvenated

Computational software that evaluates DNA samples may help in diagnosis, treatment of cancer

Children exposed to early deprivation could experience mental health problems in early adulthood

Cocaine use by fathers may negatively impact cognitive development in male offspring

Lack of methyl groups in gene body may lead to emergence of cancer

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Epigenetics News and Research

Latest Epigenetics News and Research

Genetics & Genomics - Second Edition eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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