Epigenetics News and Research

Latest Epigenetics News and Research

Scientists identify consistent epigenetic signatures in men with metastatic prostate cancer

In a genome-wide analysis of 13 metastatic prostate cancers, scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic "signatures" across all metastatic tumors in each patient.

23 Jan 2013

Studies identify cellular pathways involved in governing day-night pattern of circadian rhythms

UC Irvine-led studies have revealed the cellular mechanism by which circadian rhythms - also known as the body clock - modify energy metabolism and also have identified novel compounds that control this action. The findings point to potential treatments for disorders triggered by circadian rhythm dysfunction, ranging from insomnia and obesity to diabetes and cancer.

23 Jan 2013

Antibodies essential for dendritic cell maturation

Dendritic cells, or DCs for short, perform a vital role for the immune system: They engulf pathogens, break them down into their component parts, and then display the pieces on their surface.

23 Jan 2013

Study refocuses on how neuroblastoma tumors evolve in response to medicine and other factors

An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene mutations—mutations that would suggest new targets for neuroblastoma treatment. Instead, say the researchers, they have now refocused on how neuroblastoma tumors evolve in response to medicine and other factors.

21 Jan 2013

Researchers identify clear role for tags in mediating genetic risk for rheumatoid arthritis

In one of the first genome-wide studies to hunt for both genes and their regulatory "tags" in patients suffering from a common disease, researchers have found a clear role for the tags in mediating genetic risk for rheumatoid arthritis (RA), an immune disorder that afflicts an estimated 1.5 million American adults.

21 Jan 2013

Cancer Targets & Therapeutics Conference to take place from Feb. 25-26 in Las Vegas

With the rapid progression of molecular biology and genetics, and the subsequent emergence of many new targets, emerging targets & therapeutics provides new opportunities for the prevention and treatment of several major disease systems.

19 Jan 2013

Stress in adolescence can cause severe mental illness in young adulthood

Working with mice, Johns Hopkins researchers have established a link between elevated levels of a stress hormone in adolescence — a critical time for brain development — and genetic changes that, in young adulthood, cause severe mental illness in those predisposed to it.

18 Jan 2013

Cancer researchers solve mystery of how Chd5 protein exerts its beneficial effects

A team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, called Chd5, exerts its beneficial effects.

11 Jan 2013

Chromatin regulation not governed by a uniform histone code

In a novel use of gene knockout technology, researchers at the University of California, San Diego School of Medicine tested the same gene inserted into 90 different locations in a yeast chromosome - and discovered that while the inserted gene never altered its surrounding chromatin landscape, differences in that immediate landscape measurably affected gene activity.

4 Jan 2013

New light on how epigenetic signals may function together to determine fate of stem cell

Long-standing research efforts have been focused on understanding how stem cells, cells capable of transforming into any type of cell in the body, are capable of being programmed down a defined path to contribute to the development of a specific organ like a heart, lung, or kidney. Research from the University of North Carolina at Chapel Hill School of Medicine has shed new light on how epigenetic signals may function together to determine the ultimate fate of a stem cell.

28 Dec 2012

Range of epigenetic immunoassays from VolitionRx now available for research use

VolitionRx Limited, a life sciences company focused on developing blood-based diagnostic tests, announces the launch of NuQ, its range of research use only epigenetic immunoassays, to be available for sale at www.nucleosomics.com.

17 Dec 2012

Paternal exposure to cocaine can impair gene expression and behavior in their offspring

Research from the Perelman School of Medicine at the University of Pennsylvania and Massachusetts General Hospital (MGH) reveals that sons of male rats exposed to cocaine are resistant to the rewarding effects of the drug, suggesting that cocaine-induced changes in physiology are passed down from father to son.

17 Dec 2012

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

Scientists at Dana-Farber Cancer Institute have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, which normally are needed to spur the cancer's growth. They say the finding could lead to a new treatment for prostate cancers that are no longer controlled by hormone-blocking drugs.

14 Dec 2012

American Association of Anatomist announces winners of Young Investigator Awards

The American Association of Anatomist's (AAA) Young Investigator Awards combine three long-standing AAA awards-Bensley, Herrick, and Mossman-with the Morphological Sciences Award, all recognizing investigators in the early stages of their careers who have made important contributions to biomedical science through their research in cell/molecular biology, developmental biology, comparative neuroanatomy, or the morphological sciences.

12 Dec 2012

Epi-marks can lead to homosexuality

Epigenetics - how gene expression is regulated by temporary switches, called epi-marks - appears to be a critical and overlooked factor contributing to the long-standing puzzle of why homosexuality occurs.

12 Dec 2012

GeneTex to introduce new Histone H3 antibody

GeneTex, a leading manufacturer of antibodies and antibody-related reagents, is set to launch a new antibody against phosphorylated Histone H3.

11 Dec 2012

Acetylon announces results from selective HDAC 1/2 inhibitor preclinical study on SCD and bT

Acetylon Pharmaceuticals Inc., a leader in targeted epigenetic drug discovery and development for enhanced therapeutic outcomes, today announced results from a preclinical study of a selective histone deacetylase (HDAC) 1/2 inhibitor for the treatment of sickle cell disease (SCD) and beta-thalassemia (bT) at the 54th Annual Meeting of the American Society of Hematology (ASH), taking place in Atlanta, Georgia.

11 Dec 2012

Pfizer joins WIN Consortium to improve personalized cancer care

Worldwide Innovative Network (WIN) in personalized cancer medicine consortium today proudly announced that Pfizer, Inc (NYSE:PFE) is the first pharmaceutical company to become a member of the consortium. Founded on the recognition that greater success can be achieved through collaboration than any organization can achieve alone, the WIN Consortium is a global network of leading academic, industry, and patient advocacy organizations working to make personalized cancer care a reality for patients worldwide.

10 Dec 2012

JPND invites proposals from researchers to understand the underlying causes of neurodegenerative diseases

The EU Joint Programme - Neurodegenerative Disease Research (JPND) is inviting calls for proposals from research teams across Europe to increase understanding of the factors that put people at risk of developing neurodegenerative diseases (ND) such as Alzheimer's and also to evaluate health and social care strategies for people living with these debilitating illnesses.

10 Dec 2012

Study identifies epigenetic events critical to cancer cell survival

USC Norris Comprehensive Cancer Center research that identifies specific genes that have to be turned off in order for cancer cells to survive was named one of the top major advances in cancer research this year by the American Society of Clinical Oncology (ASCO).

7 Dec 2012

Epigenetics News and Research

Latest Epigenetics News and Research

Scientists identify consistent epigenetic signatures in men with metastatic prostate cancer

Studies identify cellular pathways involved in governing day-night pattern of circadian rhythms

Antibodies essential for dendritic cell maturation

Study refocuses on how neuroblastoma tumors evolve in response to medicine and other factors

Researchers identify clear role for tags in mediating genetic risk for rheumatoid arthritis

Cancer Targets & Therapeutics Conference to take place from Feb. 25-26 in Las Vegas

Stress in adolescence can cause severe mental illness in young adulthood

Cancer researchers solve mystery of how Chd5 protein exerts its beneficial effects

Chromatin regulation not governed by a uniform histone code

New light on how epigenetic signals may function together to determine fate of stem cell

Range of epigenetic immunoassays from VolitionRx now available for research use

Paternal exposure to cocaine can impair gene expression and behavior in their offspring

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

American Association of Anatomist announces winners of Young Investigator Awards

Epi-marks can lead to homosexuality

GeneTex to introduce new Histone H3 antibody

Acetylon announces results from selective HDAC 1/2 inhibitor preclinical study on SCD and bT

Pfizer joins WIN Consortium to improve personalized cancer care

JPND invites proposals from researchers to understand the underlying causes of neurodegenerative diseases

Study identifies epigenetic events critical to cancer cell survival

eBook: A guide to RNA sequencing eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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Digital pathology and the PathoVerse: A conversation with Dr. Singh

Epigenetics News and Research

Latest Epigenetics News and Research

eBook: A guide to RNA sequencing eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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