Epigenetics News and Research

Latest Epigenetics News and Research

Genetic influence on postmenopausal bone loss falls with age

The effect of genetics on bone loss rates in postmenopausal women reduces until the age of 65 years, after which time its influence disappears completely, according to results from a twin-based study.

8 Jun 2012

Discovery answers why mother's immune system does not reject developing fetus as foreign tissue

Researchers at NYU School of Medicine have made an important discovery that partially answers the long-standing question of why a mother's immune system does not reject a developing fetus as foreign tissue.

8 Jun 2012

Nrf2-KEAP1 protein may play a role in diabetic retinopathy

A Wayne State University researcher believes a protein that fails to reach the nucleus of retinal cells may play a role in causing eye disease in people with diabetes.

8 Jun 2012

CDI introduces MyCell Services

Cellular Dynamics International, Inc. (CDI), the world's largest commercial producer of human induced pluripotent stem (iPS) cell lines and tissue cells, today announced the launch of its MyCell Services.

7 Jun 2012

New research into cell-damaging effects of Huntington's disease

New research into the cell-damaging effects of Huntington's disease suggests a potentially new approach for identifying possible therapeutic targets for treating the nerve-destroying disorder.

7 Jun 2012

Study identifies existence of an antitumor molecule that originates within SMYD3 oncogene

A common point in all human tumors is that they produce an activation of oncogenes, genes that cause cancer and they also cause a loss of function of the protective genes, called anti-oncogenes or tumour suppressor genes. Normally both categories of anticancer and procancer genes are in different regions of our chromosomes.

6 Jun 2012

DFG to establish 20 CRCs by 1 July 2012

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is to establish 20 Collaborative Research Centres (CRCs) by 1 July 2012. This decision was taken by the Grants Committee at its spring session in Bonn. The new CRCs will receive funding totalling 176 million euros (including a 20 percent programme allowance for indirect project costs) for the initial 4-year funding period.

30 May 2012

MDxHealth announces availability of ConfirmMDx for Prostate Cancer test

MDxHealth SA, a leading molecular diagnostic company that develops and commercializes epigenetic tests to support cancer treatment, today announced it has presented data demonstrating that its epigenetic ConfirmMDx for Prostate Cancer test can aid urologists in identifying patients who may avoid a repeat prostate biopsy.

23 May 2012

Science journal’s NEWSFOCUS section describes recent advances in sequencing technology

Rapid DNA sequencing may soon become a routine part of each individual's medical record, providing enormous information previously sequestered in the human genome's 3 billion nucleotide bases. This week's NEWSFOCUS section of the journal Science describes recent advances in sequencing technology.

From Oxford Nanopore Technologies 23 May 2012

Researchers identify novel base modification in RNA

Over the past decade, research in the field of epigenetics has revealed that chemically modified bases are abundant components of the human genome and has forced us to abandon the notion we've had since high school genetics that DNA consists of only four bases.

18 May 2012

Radiation oncology researchers revise glioblastoma classification system

Radiation oncology researchers have revised the system used by doctors since the 1990s to determine the prognosis of people with glioblastoma, which is the most devastating of malignant brain tumors.

17 May 2012

Mass. Eye and Ear announces recipients of 2012 Curing Kids Fund grants

The Mass. Eye and Ear Curing Kids fund has awarded grants for research projects that aim to help the brain locate sound, identify genes that cause congenital blindness, cure deafness through hair cell regeneration, and improve treatment for childhood eye cancer.

16 May 2012

Chromatin compaction required for proper embryonic stem cell differentiation

New research findings show that embryonic stem cells unable to fully compact the DNA inside them cannot complete their primary task: differentiation into specific cell types that give rise to the various types of tissues and structures in the body.

11 May 2012

Oral nutriceutical restores vision to otherwise hopeless patients facing permanent loss

There may be new found hope for patients whose vision is threatened when medicine injected directly into the eyes fails to cause abnormal blood vessels to recede. While injectable drugs called angiogenesis (an-gee-oh-jen-esis) inhibitors are considered a modern miracle and have become the standard of care for patients with the fast-progressive form of macular degeneration, they are not foolproof.

7 May 2012

Researchers separate low and high-PSA prostate cancer cells

Prostate cancer cells that defy treatment and display heightened tumor-generating capacity can be identified by levels of prostate specific antigen (PSA) expressed in the tumor cells, a research team led by scientists at The University of Texas MD Anderson Cancer Center reports in the May 3 edition of Cell Stem Cell.

7 May 2012

A test to predict breast cancer many years before the disease is diagnosed

Ultimately the findings, in the journal Cancer Research, could lead to a simple blood test to screen women, they say. The test looks for how genes are altered by environmental factors like alcohol and hormones - a process known as epigenetics. One in five women is thought to have such a genetic “switch” that doubles breast cancer risk say researchers.

3 May 2012

CHR-3996 pill shows promise against advanced cancers

Scientists have shown that a brand new type of cancer pill that exploits the emerging field of epigenetics is safe for human use, according to a Phase I trial reported today in Clinical Cancer Research.

2 May 2012

JCO publishes Syndax erlotinib-entinostat Phase 2 study for advanced non-small cell lung cancer

Syndax Pharmaceuticals, Inc., a late-stage oncology company focused on the clinical development of epigenetic therapies in solid tumors, announced that previously reported results from ENCORE 401, a randomized, placebo controlled Phase 2 study of erlotinib with or without entinostat in advanced non-small cell lung cancer patients were published in the Journal of Clinical Oncology (JCO).

30 Apr 2012

Detrimental effect of tetracycline on male reproductive function, sperm viability of pseudoscorpions

In a paper published today in Nature's open access journal Scientific Reports, researchers at the University of Nevada, Reno report that male pseudoscorpions treated with the antibiotic tetracycline suffer significantly reduced sperm viability and pass this toxic effect on to their untreated sons. They suggest that a similar effect could occur in humans and other species.

30 Apr 2012

PLUS Diagnostics, MDxHealth partner to co-promote ConfirmMDx for Prostate Cancer

MDxHealth SA, a leading molecular diagnostic company that develops and commercializes epigenetic tests to support cancer treatment, and PLUS Diagnostics today announced that they have entered into an agreement to co-promote MDxHealth's ConfirmMDx for Prostate Cancer test in the United States.

26 Apr 2012

Epigenetics News and Research

Latest Epigenetics News and Research

Genetic influence on postmenopausal bone loss falls with age

Discovery answers why mother's immune system does not reject developing fetus as foreign tissue

Nrf2-KEAP1 protein may play a role in diabetic retinopathy

CDI introduces MyCell Services

New research into cell-damaging effects of Huntington's disease

Study identifies existence of an antitumor molecule that originates within SMYD3 oncogene

DFG to establish 20 CRCs by 1 July 2012

MDxHealth announces availability of ConfirmMDx for Prostate Cancer test

Science journal’s NEWSFOCUS section describes recent advances in sequencing technology

Researchers identify novel base modification in RNA

Radiation oncology researchers revise glioblastoma classification system

Mass. Eye and Ear announces recipients of 2012 Curing Kids Fund grants

Chromatin compaction required for proper embryonic stem cell differentiation

Oral nutriceutical restores vision to otherwise hopeless patients facing permanent loss

Researchers separate low and high-PSA prostate cancer cells

A test to predict breast cancer many years before the disease is diagnosed

CHR-3996 pill shows promise against advanced cancers

JCO publishes Syndax erlotinib-entinostat Phase 2 study for advanced non-small cell lung cancer

Detrimental effect of tetracycline on male reproductive function, sperm viability of pseudoscorpions

PLUS Diagnostics, MDxHealth partner to co-promote ConfirmMDx for Prostate Cancer

eBook: A guide to RNA sequencing eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Epigenetics News and Research

Latest Epigenetics News and Research

eBook: A guide to RNA sequencing eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Newsletters you may be interested in