Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Polygenic risk scores from multi-population data could improve IBD predictions

Using genetic data from nearly 30,000 people, Mount Sinai researchers have built risk scores from a combination of datasets representing distinct ancestral populations that improve prediction of risk for inflammatory bowel diseases (IBD) including Crohn's disease and ulcerative colitis. The study was published in Gastroenterology on December 24.

24 Dec 2020

Phase 2/3 COVID-19 study evaluates safety, potential identification of preliminary efficacy signals

Top-line data from the 270-patient global Phase 2/3 COVID-19 study expected Q1/2021. Top-line data from the 40-patient U.S. Phase 2 study of opaganib in severe COVID-19 expected in the coming days; this non-powered study was designed to evaluate safety and potential identification of preliminary efficacy signals in support of the global Phase 2/3 study of opaganib.

23 Dec 2020

Research shows how colanic acid extends lifespan in C. elegans

Baylor College of Medicine researcher Meng Wang had already shown that bacteria that make a metabolite called colanic acid (CA) could extend the lifespan of worms in her lab by as much as 50%, but her collaboration with Rice University synthetic biologist Jeffrey Tabor is providing tools to answer the bigger question of how the metabolite imparts longer life.

22 Dec 2020

Nanoplastics affect composition and diversity of human intestinal microbiome

We live in a world invaded by plastic. Its role as a chemically stable, versatile and multi-purpose fostered its massive use, which has finally translated into our current situation of planetary pollution.

22 Dec 2020

Researchers establish BRIDGES program to synergize diagnostic efforts, patient outcome management

For over 20 years, the Genetics Service at the KK Women's and Children's Hospital (KKH) has been providing clinical care to patients with genetic disorders.

22 Dec 2020

Antibiotics for C-sections are effective when given after clamping the umbilical cord

Antibiotics for cesarean section births are just as effective when they're given after the umbilical cord is clamped as before clamping – the current practice – and could benefit newborns' developing microbiomes, according to Rutgers co-authored research.

21 Dec 2020

The weak spot of colon cancer stem cells

Colon cancer stem cells have one weak spot: the enzyme Mll1. An MDC team led by Walter Birchmeier has now shown in Nature Communications that blocking this protein prevents the development of new tumors in the body.

21 Dec 2020

Researchers demonstrate potential preventive treatment for Crohn's disease

A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease.

21 Dec 2020

Researchers investigate microbiome-mediated therapies for aging and health span

Texas Biomedical Research Institute Associate Professor Corinna Ross, PhD, is a principal investigator on a $3.38 million National Institutes of Health multi-investigator grant to study "microbiome-mediated therapies for aging and healthspan" in marmosets, which are small monkeys native to South America and are becoming increasingly more important in aging and infectious disease research.

18 Dec 2020

WEHI researchers suggest potential new approach to treat stomach cancer

WEHI researchers have identified a key molecular regulator involved in the progression and spread of stomach cancer, suggesting a potential new approach to treat this devastating disease.

17 Dec 2020

Mother's diet while breastfeeding can shape the profile of human milk oligosaccharides

Research has shown that human milk is the optimal nutrition source for neonates and infants. It confers protection against both immediately life-threatening infant diseases such as necrotizing enterocolitis, as well as later onset diseases in adults, like obesity, diabetes and inflammatory bowel disease.

16 Dec 2020

Study shows rising incidence of esophageal adenocarcinoma in younger adults

Esophageal adenocarcinoma is occurring more frequently in adults under age 50, and these younger adults are more likely to be diagnosed at advanced stages.

16 Dec 2020

Eating avocado as part of daily diet can help improve gut health, shows study

Eating avocado as part of your daily diet can help improve gut health, a new study from University of Illinois shows. Avocados are a healthy food that is high in dietary fiber and monounsaturated fat. However, it was not clear how avocados impact the microbes in the gastrointestinal system or "gut."

16 Dec 2020

RedHill Biopharma announces promising preliminary results from opaganib study

TEL AVIV, Israel and RALEIGH, NC, December 15, 2020, RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced promising preliminary results from a preclinical study with opaganib.

15 Dec 2020

Texas Biomed to investigate the effects of cannabinoids on HIV-associated neurocognitive disorder

The National Institutes of Health (NIH) awarded Professor Mahesh Mohan, D.V.M., Ph.D., and collaborators more than $3.5 million over five years to investigate the effects of cannabinoids on Human Immunodeficiency Virus (HIV) associated neurocognitive disorder (HAND).

11 Dec 2020

Beta-blockers show anti-inflammatory effects in cirrhosis

Approximately 170,000 people die every year in Europe from the direct consequences of advanced chronic liver disease (cirrhosis).

10 Dec 2020

Researchers pinpoint key factors to ensure successful fecal microbiota transplants

Could number two be number one when it comes to combating recurrent Clostridium difficile (CDI) infections?Using genetic material analysis and machine learning, UBC researchers have pinpointed several key factors to ensure successful fecal microbiota transplants (FMT), which have proven successful in treating bacterial infections in the gut including illnesses like C. difficile, Crohn's Disease, Colitis and even obesity, explains lead author Negin Kazemian.

10 Dec 2020

New model shows how bacteria behave in multiple scenarios with common spatial patterns

Bacteria is all around us - not just in bathrooms or kitchen counters, but also inside our bodies, including in tumors, where microbiota often flourish.

10 Dec 2020

Modulation of oral microbiota impacts the cardiovascular benefits of sport

Exercise plays a key role in maintaining good physical and mental health throughout life. There is an increasing amount of scientific evidence that some of the immune system and metabolism benefits provided by sport are related to the thousands of millions of bacteria that colonize the digestive tract, from the mouth to the intestines, known as microbiota.

9 Dec 2020

UofL receives DoD funding to develop a nasal spray for preventing COVID-19

The University of Louisville has received funding from the U.S. Department of Defense (DoD) to develop a nasal spray to prevent serious viral respiratory infections such as COVID-19 using Q-Griffithsin, a drug compound developed and co-owned by UofL.

9 Dec 2020

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Polygenic risk scores from multi-population data could improve IBD predictions

Phase 2/3 COVID-19 study evaluates safety, potential identification of preliminary efficacy signals

Research shows how colanic acid extends lifespan in C. elegans

Nanoplastics affect composition and diversity of human intestinal microbiome

Researchers establish BRIDGES program to synergize diagnostic efforts, patient outcome management

Antibiotics for C-sections are effective when given after clamping the umbilical cord

The weak spot of colon cancer stem cells

Researchers demonstrate potential preventive treatment for Crohn's disease

Researchers investigate microbiome-mediated therapies for aging and health span

WEHI researchers suggest potential new approach to treat stomach cancer

Mother's diet while breastfeeding can shape the profile of human milk oligosaccharides

Study shows rising incidence of esophageal adenocarcinoma in younger adults

Eating avocado as part of daily diet can help improve gut health, shows study

RedHill Biopharma announces promising preliminary results from opaganib study

Texas Biomed to investigate the effects of cannabinoids on HIV-associated neurocognitive disorder

Beta-blockers show anti-inflammatory effects in cirrhosis

Researchers pinpoint key factors to ensure successful fecal microbiota transplants

New model shows how bacteria behave in multiple scenarios with common spatial patterns

Modulation of oral microbiota impacts the cardiovascular benefits of sport

UofL receives DoD funding to develop a nasal spray for preventing COVID-19

Microbiology eBook

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Gastrointestinal Health News and Research

Latest Gastrointestinal Health News and Research

Microbiology eBook

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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