Gene News and Research

Latest Gene News and Research

Study reveals serotonin's role in ependymoma tumor growth

Do neurons play a role in brain tumor growth and development? Scientists at St. Jude Children's Research Hospital and Baylor College of Medicine have evidence showing that, for childhood ependymomas, they do.

31 Jul 2024

Powerful visualization technologies offer new insight into understanding muscle contraction in humans

The connections between the nervous system and muscles develop differently across the kingdom of life.

31 Jul 2024

Vegan diet may slow aging

Vegan diets showed short-term benefits on epigenetic aging compared to omnivorous diets in healthy twins, with reduced epigenetic age metrics observed in the vegan group. However, telomere length and overall mitotic clock values remained unchanged for both diets.

31 Jul 2024

Study links tissue-resident memory T cells to improved lung cancer outcomes

An extensive analytical study performed at the Terasaki Institute and published in Frontiers in Immunology highlights the crucial role of tissue-resident memory T cells and how they influence the immune environment of patients with non-small cell lung cancer and their overall prognosis.

30 Jul 2024

Genetic loss of miR-205 boosts mammary gland development in mice, reveals new insights into breast cancer suppression

Genetic loss of miR-205 in mice enhances mammary gland development and branching, challenging previous lethality findings and highlighting its onco-suppressive functions.

30 Jul 2024

Researchers identify key genetic variants linked to ALS recovery

Though exceedingly rare, some people diagnosed with amyotrophic lateral sclerosis (ALS) partially or fully recover from the lethal neurodegenerative disease.

30 Jul 2024

Targeting oncogenic transcription factors to develop potential new cancer treatments

A new study from the University of Michigan Health Rogel Cancer Center furthers research that suggests the potential of developing new cancer treatments to target oncogenic transcription factors by indirectly affecting their ability to access enhancer DNA in chromatin.

30 Jul 2024

Review highlights the interplay of TGF-β and HIPPO pathways in liver regeneration and disease

The liver's ability to communicate with other organs is crucial for maintaining homeostasis, particularly through signaling pathways.

30 Jul 2024

Study finds plasma biomarkers can predict dementia risk

A study in JAMA explores the potential of plasma biomarkers for Alzheimer’s disease and cardiometabolic risk factors to predict other types of dementia, highlighting the importance of early diagnosis and combining biomarkers with demographic data for improved accuracy.

30 Jul 2024

Epigenetic reprogramming and hypothalamic changes in metabolic syndrome

Metabolic syndrome (MetS) is a multifaceted disorder that impacts approximately 20–25% of the global population.

30 Jul 2024

Study finds higher levels of lncRNAs in the testes than previously estimated

Researchers at the University of Toronto have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes.

30 Jul 2024

New prognostic marker identified for gastric cancer recurrence risk

Surgical removal of the tumor is considered the basis for curing gastric cancer. However, 40 per cent of patients who have undergone surgery suffer a relapse within two years.

30 Jul 2024

Genetic variants associated with Parkinson's more common than estimated

New research has found that genetic variants associated with Parkinson's disease (PD) are more common than researchers previously believed. Investigators in the Parkinson's Foundation-backed PD GENEration study – which reached its goal of 15,000 participants ahead of schedule this spring – found that 13% of participants have a genetic form of PD, which is a significant observation compared to long-standing estimates. Results from the first 3.5 years of the study, which examined a broad North American cohort, were published in the peer-reviewed scientific journal Brain.

30 Jul 2024

Garlic as a potent weapon against atherosclerosis

Researchers identified garlic's potential to treat atherosclerosis by regulating ferroptosis and reducing lipid peroxidation, offering a safer alternative to current treatments.

29 Jul 2024

DNA repair gene mutations predict bladder cancer response to neoadjuvant chemotherapy

An analysis of pre-treatment tumor specimens from 105 patients with localized muscle-invasive bladder cancer found that the presence of a mutation in any one of three genes, all known to be involved in DNA damage repair, was associated with complete pathologic response to cisplatin-based neoadjuvant chemotherapy as measured by pathological downstaging at the time of bladder surgery.

29 Jul 2024

Transthyretin protein levels linked to heart failure and mortality

Physician-scientists from the University of Alabama at Birmingham Marnix E. Heersink School of Medicine have uncovered significant findings regarding the impact of transthyretin, or TTR, protein levels on heart disease risk.

29 Jul 2024

Deciphering miRNA-mediated regulation of liver regeneration: New insights

The liver, a vital organ involved in numerous essential physiological processes such as bile production, plasma protein synthesis, nutrient absorption, detoxification, vitamin storage, macronutrient metabolism, and immune support, has a remarkable regenerative capacity.

29 Jul 2024