Genetics News and Research

Latest Genetics News and Research

Unmasking Nrf2 as a key driver of treatment resistance in osteosarcoma

A deeper understanding of osteosarcoma, the most common primary malignant bone tumor affecting children and adolescents, is reshaping strategies for overcoming treatment resistance.

20 Apr 2025

Exploring the impact of R-loops on genome integrity and disease

This new review article highlights the pivotal and paradoxical role of R-loops in maintaining genomic stability while simultaneously posing risks to it.

19 Apr 2025

Small peptides play big role in halting bacterial translation

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions.

18 Apr 2025

Researchers identify gene targets that may protect against Alzheimer’s

A study published in the American Journal of Human Genetics by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital provides solutions to the pressing need to identify factors that influence Alzheimer's disease (AD) risk or resistance while providing an avenue to explore potential biological markers and therapeutic targets.

17 Apr 2025

KFF Health News' 'What the Health?': On autism, it’s the secretary’s word vs. CDC’S

The secretary of Health and Human Services, Robert F. Kennedy Jr., contradicted his agency's researchers this week with unsubstantiated or outright false claims about autism spectrum disorder and those with the condition.

17 Apr 2025

Researchers use algorithm to pinpoint disease risk mutations in noncoding DNA

Researchers from Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania (Penn Medicine) have successfully employed an algorithm to identify potential mutations which increase disease risk in the noncoding regions our DNA, which make up the vast majority of the human genome.

17 Apr 2025

Study unveils genetic pathway leading to cleft lip and palate formation

Cleft lip and cleft palate are among the most common birth defects, occurring in about one in 1,050 births in the United States.

17 Apr 2025

Affectionate mothering linked to positive personality development

Affectionate mothering in childhood may have a lasting impact on important personality traits, potentially influencing life outcomes such as educational achievement, economic success, and health and well-being, according to research published by the American Psychological Association.

17 Apr 2025

Seasonal air pollution found to undermine IVF success

Exposure to fine particulate matter during fertility treatment windows—especially in winter—negatively impacts pregnancy and live birth rates

17 Apr 2025

Mount Sinai Fuster Heart Hospital earns national recognition for patient care excellence

The Mount Sinai Fuster Heart Hospital's cardiology faculty practice has received the 2024 Human Experience Pinnacle of Excellence Award from Press Ganey, one of the nation's leading patient experience organizations.

16 Apr 2025

Sex and age play key roles in dementia biomarker levels

A new study has found important clues about the roles age, sex, hormonal changes and genetics play in how certain biomarkers for dementia are expressed in the blood, according to a study published on April 16, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

16 Apr 2025

New tool simplifies genomic research and boosts medical breakthroughs

A University of Virginia School of Medicine scientist and collaborators have developed a much-needed new tool to increase the efficiency of genomic research and accelerate the development of new ways to improve human health.

16 Apr 2025

New genetic clues uncovered in epilepsy drug resistance

Certain common genetic changes might make some people with focal epilepsy less responsive to seizure medications, finds a new global study led by researchers at UCL and UTHealth Houston.

16 Apr 2025

New discoveries explain how DNA repair signals are controlled

Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question.

16 Apr 2025

Multiple myeloma care improved using innovative optical genome mapping

Researchers have demonstrated the potential of the innovative optical genome mapping (OGM) technique for the diagnosis, prognosis, and therapeutic management of multiple myeloma.

15 Apr 2025

Inherited genetic variants play crucial role in cancer development and behavior

A new multicenter study by researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with the National Cancer Institute-funded Clinical Proteomic Tumor Analysis Consortium (CPTAC) and colleagues around the world, has discovered that the genes we are born with-known as germline genetic variants-play a powerful, underappreciated role in how cancer develops and behaves.

15 Apr 2025

Genetic diversity of malaria parasite challenges one size fits all strategies

Despite decades of efforts focused on mosquito eradication, drug therapies, and vaccines, malaria remains hard to beat, especially in Africa.

11 Apr 2025

Breakthrough in chicken genomics offers hope against avian influenza

An international team of researchers led by Professor Huaijun Zhou from the UC Davis Department of Animal Science has created the first-ever detailed map of how genes are regulated in chickens - a breakthrough that could help scientists breed birds that are more resistant to diseases like avian influenza.

10 Apr 2025

New data-sparse model accurately predicts individual glycemic responses

If you eat a snack - a meatball, say, or a marshmallow - how will it affect your blood sugar? It's a surprisingly tricky question: the body's glycemic response to different foods varies based on individual genetics, microbiomes, hormonal fluctuations, and more.

10 Apr 2025

Unlocking the power of MDA5 protein modifications in antiviral defense

Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication.

10 Apr 2025