Headache

In medicine a headache or cephalalgia is a symptom of a number of different conditions of the head. Some of the causes are benign while others are medical emergencies.

Does the Location of a Headache Matter?

The location of a headache may be an important factor in identifying the cause of certain types of headaches, but not in all.

What is Muscle Contraction Headache?

Headache Behind the Eyes: Understanding the Causes

Can Contact Lenses Cause Headaches?

Frequent Headaches after a Traumatic Brain Injury

Cluster Headaches: Treatment and Prevention

What is Medication Overuse Headache?

Biofeedback Therapy for Headaches

See more featured articles »

Headaches in Children and Teenagers

Headache Evaluation in Children and Teenagers

Migraine with Aura vs. Migraine without Aura

Headache Related to Eye Problems

Latest Headache News and Research

Frequent soccer heading linked to alterations within the folds of the brain

In amateur soccer players, more frequent heading, or using the head to control or pass the ball, is linked to alterations within the folds of the brain, according to a study published on September 17, 2025, in Neurology, the medical journal of the American Academy of Neurology.

17 Sep 2025

Physical frailty linked to higher dementia risk

A new study suggests that physical frailty may contribute to the development of dementia. The study was published on September 17, 2025, in Neurology®, the medical journal of the American Academy of Neurology.

17 Sep 2025

Lifestyle changes show promise in preventing cognitive decline and Alzheimer’s disease

An estimated 7.2 million Americans over age 65 currently live with Alzheimer's disease (AD). That number is expected to nearly double to 13.8 million by 2060.

16 Sep 2025

Specially formulated eye drops may offer a simple solution for presbyopia patients

Everybody develops presbyopia as they age – a difficulty in focusing on near objects and text – and often have to resort to reading glasses. However, the solution might be as simple as using special eye drops two or three times a day.

15 Sep 2025

Ketogenic diets may lower migraine frequency and medication use

This narrative review argues that the migraine brain is hypometabolic, with converging evidence of mitochondrial dysfunction, impaired glucose handling, neuroinflammation, microbiome shifts, and obesity-related pathways. It proposes ketogenic diets as a plausible preventive strategy that may reduce monthly migraine days and medication use, while emphasizing the need for larger, rigorous randomized trials and careful clinical oversight.

14 Sep 2025

Elinzanetant reduces hot flashes in menopause

The OASIS-3 trial demonstrates elinzanetant's effectiveness in alleviating menopausal symptoms, reducing hot flashes significantly over a year-long study.

11 Sep 2025

Chronic insomnia linked to faster cognitive decline and brain changes

People with chronic insomnia may experience faster declines in memory and thinking skills as they age-along with brain changes that can be seen on imaging scans-than people who do not have chronic insomnia, according to a study published in the September 10, 2025, issue of Neurology, the medical journal of the American Academy of Neurology.

10 Sep 2025

Can an allergy spray help prevent COVID-19?

Researchers determine the efficacy and safety of azelastine nasal spray for preventing SARS-CoV-2 infection in healthy adults.

8 Sep 2025

Too much caffeine may worsen stress for students hooked on studying

Findings suggest that caffeine intake can worsen anxiety and depression in students, emphasizing the need for balanced consumption and mental health support.

5 Sep 2025

Study links high intake of artificial sweeteners to faster cognitive decline

Some sugar substitutes may come with unexpected consequences for long-term brain health, according to a study published in the September 3, 2025, issue of Neurology, the medical journal of the American Academy of Neurology.

3 Sep 2025

Sinus surgery proves more effective than antibiotics for chronic rhinosinusitis

Sinus surgery is more effective than antibiotics at treating chronic rhinosinusitis, according to a major clinical trial led by University College London (UCL) along with academics at the University of East Anglia and Guy's and St Thomas' NHS Foundation Trust.

28 Aug 2025

Native Hawaiian and Pacific Islander people face highest stroke rates in the U.S.

A new study found that Native Hawaiian or Pacific Islander people had the highest rate of stroke among people from other race and ethnic groups, with a rate more than three times higher than that of white people.

28 Aug 2025

Hormone therapy type may influence postmenopausal cognitive health

The type of estradiol-based hormone therapy taken during and after menopause, such as patches or pills, may be associated with differences in memory performance, according to a study published on August 27, 2025, in Neurology, the medical journal of the American Academy of Neurology.

28 Aug 2025

Evidence review questions ketamine’s role in chronic pain treatment

A Cochrane review assessed ketamine and other NMDA receptor antagonists for chronic non-cancer pain. The evidence was low to very low certainty, showing no clear pain relief and potential adverse effects with intravenous ketamine.

21 Aug 2025

Metabolic syndrome linked to higher risk of Parkinson's disease

Having a larger waistline, high blood pressure and other risk factors that make up metabolic syndrome is associated with an increased risk of Parkinson's disease, according to a study published on August 20, 2025, in Neurology, the medical journal of the American Academy of Neurology.

20 Aug 2025

How a Réunion Island outbreak sparked France’s record chikungunya season

Mainland France recorded its earliest-ever local chikungunya outbreaks in May 2025, with 10 clusters (27 cases) across five regions, driven by travelers importing the virus from Réunion Island. The surge highlights growing vulnerability to mosquito-borne diseases in Europe as Aedes albopictus expands northward.

18 Aug 2025

2025 Chikungunya outbreak: A global health challenge

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus causing fever, severe joint pain, rash, and muscle aches, mainly transmitted by Aedes mosquitoes. As of 2025,

From Sino Biological Inc. 18 Aug 2025

Prenatal acetaminophen linked to higher risk of autism and ADHD

Researchers at the Icahn School of Medicine at Mount Sinai have found that prenatal exposure to acetaminophen may increase the risk of neurodevelopmental disorders, including autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD), in children.

14 Aug 2025

Researchers find CFI deficiency alarmingly high in old order Amish

Researchers from Children's Hospital of Philadelphia (CHOP) and the Clinic for Special Children found that complement factor I (CFI) deficiency, an ultra-rare genetic disorder that can cause debilitating neuroinflammation, is more than 4500 times more likely to be found in individuals of Old Order Amish ancestry than the rest of the global population.

13 Aug 2025

Pregnancy complications may signal early stroke risk

Experiencing complications during pregnancy is linked with a higher risk of stroke before age 50, according to a study published August 6, 2025, in Neurology®, the medical journal of the American Academy of Neurology.

6 Aug 2025