Headache

In medicine a headache or cephalalgia is a symptom of a number of different conditions of the head. Some of the causes are benign while others are medical emergencies.

Does the Location of a Headache Matter?

The location of a headache may be an important factor in identifying the cause of certain types of headaches, but not in all.

Headache Related to Eye Problems

What is Medication Overuse Headache?

Headache Behind the Eyes: Understanding the Causes

Frequent Headaches after a Traumatic Brain Injury

Headache Evaluation in Children and Teenagers

What is Muscle Contraction Headache?

See more featured articles »

Biofeedback Therapy for Headaches

Can Contact Lenses Cause Headaches?

Migraine with Aura vs. Migraine without Aura

Cluster Headaches: Treatment and Prevention

Headaches in Children and Teenagers

Latest Headache News and Research

Evidence review questions ketamine’s role in chronic pain treatment

A Cochrane review assessed ketamine and other NMDA receptor antagonists for chronic non-cancer pain. The evidence was low to very low certainty, showing no clear pain relief and potential adverse effects with intravenous ketamine.

21 Aug 2025

Metabolic syndrome linked to higher risk of Parkinson's disease

Having a larger waistline, high blood pressure and other risk factors that make up metabolic syndrome is associated with an increased risk of Parkinson's disease, according to a study published on August 20, 2025, in Neurology, the medical journal of the American Academy of Neurology.

20 Aug 2025

How a Réunion Island outbreak sparked France’s record chikungunya season

Mainland France recorded its earliest-ever local chikungunya outbreaks in May 2025, with 10 clusters (27 cases) across five regions, driven by travelers importing the virus from Réunion Island. The surge highlights growing vulnerability to mosquito-borne diseases in Europe as Aedes albopictus expands northward.

18 Aug 2025

2025 Chikungunya outbreak: A global health challenge

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus causing fever, severe joint pain, rash, and muscle aches, mainly transmitted by Aedes mosquitoes. As of 2025,

From Sino Biological Inc. 18 Aug 2025

Prenatal acetaminophen linked to higher risk of autism and ADHD

Researchers at the Icahn School of Medicine at Mount Sinai have found that prenatal exposure to acetaminophen may increase the risk of neurodevelopmental disorders, including autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD), in children.

14 Aug 2025

Researchers find CFI deficiency alarmingly high in old order Amish

Researchers from Children's Hospital of Philadelphia (CHOP) and the Clinic for Special Children found that complement factor I (CFI) deficiency, an ultra-rare genetic disorder that can cause debilitating neuroinflammation, is more than 4500 times more likely to be found in individuals of Old Order Amish ancestry than the rest of the global population.

13 Aug 2025

Pregnancy complications may signal early stroke risk

Experiencing complications during pregnancy is linked with a higher risk of stroke before age 50, according to a study published August 6, 2025, in Neurology®, the medical journal of the American Academy of Neurology.

6 Aug 2025

Flu virus triggers neuropsychiatric symptoms not the medication

For decades, medical professionals debated whether a common antiviral medication used to treat flu in children caused neuropsychiatric events or if the infection itself was the culprit.

4 Aug 2025

Subtle warning signs of MS can appear 15 years before diagnosis

The earliest warning signs of multiple sclerosis (MS) may emerge more than a decade before the first classical neurological symptoms occur, according to new research from the University of British Columbia.

1 Aug 2025

Promising new male birth control pill could be taken every three days

YCT-529, a novel non-hormonal male contraceptive, demonstrates safety and tolerability in early trials, offering a potential solution for male birth control.

28 Jul 2025

Which GLP-1 meds have the most side effects? Study of 60,000 Facebook posts gives answers

Researchers analyzed nearly 60,000 public Facebook posts to identify real-world adverse events linked to GLP-1 receptor agonist (GLP-1 RA) medications. Gastrointestinal symptoms were most common, while mental health concerns and tirzepatide-specific side effects were also flagged.

28 Jul 2025

Study finds continued use of risky antiseizure drugs during pregnancy

Despite evidence of the risk of malformations at birth, or birth defects, use of some antiseizure drugs during pregnancy has persisted, according to a study published on July 23, 2025, in Neurology, the medical journal of the American Academy of Neurology.

24 Jul 2025

Aging skin buckles under pressure leading to wrinkles

Aging skin stretches, contracts and buckles under pressure – and that's how wrinkles form, according to new experimental evidence from scientists at Binghamton University, State University of New York.

22 Jul 2025

Hispanic people more likely to develop peripheral neuropathy than white adults

Hispanic people have an increased risk of peripheral neuropathy compared to white people that cannot be explained by many health, lifestyle and social risk factors, according to a study published July 16, 2025, in Neurology, the medical journal of the American Academy of Neurology.

16 Jul 2025

Taking specific antiseizure drugs during pregnancy linked to increased risk of malformations at birth

A new study that examined older and newer medications to treat seizures has found that using some medications during pregnancy is linked to an increased risk of malformations at birth, or birth defects.

16 Jul 2025

Medieval remedies show surprising parallels to modern wellness trends

It turns out the Dark Ages weren't all that dark! According to new research, medieval medicine was way more sophisticated than previously thought, and some of its remedies are trending today on TikTok.

16 Jul 2025

Tirzepatide tops the charts for blood sugar and weight loss in type 2 diabetes

A large network meta-analysis ranked eight GLP-1 receptor agonists for glycemic, weight, and safety outcomes in adults with type 2 diabetes. Tirzepatide demonstrated the greatest efficacy for glucose control and weight loss, while liraglutide offered the lowest hypoglycemia risk.

7 Jul 2025

Can saffron treat Alzheimer’s and depression?

Saffron shows promise as a natural treatment for depression and cognitive decline, performing as well as standard drugs in clinical trials. However, more rigorous studies are needed before saffron can be recommended in mainstream psychiatric and dementia care.

26 Jun 2025

Sleep deficiency worsens pain mechanisms in migraine sufferers

The mechanisms in the brain that should reduce pain don’t work as well in people with migraine when they haven’t gotten enough sleep.

26 Jun 2025

Living in disadvantaged neighborhoods linked to Alzheimer’s biomarkers

People living in more disadvantaged neighborhoods may be more likely to have biomarkers for inflammation and Alzheimer's disease, according to a study published June 25, 2025, in Neurology, the medical journal of the American Academy of Neurology.

26 Jun 2025