Heart Disease News and Research

Latest Heart Disease News and Research

Merck wins third FOSAMAX bellwether trial

Merck & Co., Inc. today said a federal court jury in New York found in its favor in the Graves v. Merck case, rejecting the claims of a Florida woman who blamed her dental and jaw related problems on her FOSAMAX use. With today's verdict, Merck has won three of the first four bellwether cases in the FOSAMAX litigation.

20 Nov 2010

FDA-approved anti-parasite drug blocks Wnt signaling pathway in colon cancer

An old pinworm medicine is a new lead in the search for compounds that block a signaling pathway implicated in colon cancer. The findings, reported by Vanderbilt University Medical Center researchers in the November issue of Nature Chemical Biology, suggest a fresh approach for developing therapeutics that target the pathway.

20 Nov 2010

Childhood obesity linked to adult metabolic abnormalities and cardiovascular disease

Mounting evidence linking childhood obesity to an increasing risk of obesity, heart disease, type 2 diabetes, and other cardiovascular and metabolic disorders in adulthood is clearly presented in a comprehensive review article in the current issue of Childhood Obesity, published by Mary Ann Liebert, Inc. The article is available free online.

19 Nov 2010

Medtronic's Valiant Stent System effective for thoracic aortic aneurysms treatment

An implantable medical device used in the minimally invasive treatment of thoracic aortic aneurysms, the Valiant Thoracic Stent Graft System from Medtronic, Inc., delivered strong results through 30 days of patient follow-up in the company's U.S. pivotal study, according to clinical data presented at VEITHsymposium.

19 Nov 2010

Boston Scientific's CRT-Ds, ICDs receive CE Mark approval

Boston Scientific Corporation today announced CE Mark approval of its INCEPTA, ENERGEN and PUNCTUA cardiac resynchronization therapy defibrillators and implantable cardioverter defibrillators.

19 Nov 2010

MedStart Summer Enrichment Program helps students better understand medical conditions: Studies

Two new studies have shown that a unique program in East Harlem that helps middle school students learn practical health skills and gain a better understanding of medical conditions, such as diabetes and hypertension, resulted in increased interest in college attendance and medical careers among the students who attended the program.

19 Nov 2010

Fifth gene defect, 47 DNA regions linked to thoracic aortic disease: Researchers

Discovery of a fifth gene defect and the identification of 47 DNA regions linked to thoracic aortic disease are the subject of studies released this month involving researchers at The University of Texas Health Science Center at Houston.

19 Nov 2010

Acacia subsidiary receives patents for wireless physiological monitoring technology

Acacia Research Corporation announced today that a subsidiary has acquired 11 patents for wireless physiological monitoring technology.

19 Nov 2010

Research suggests new therapeutic approach to prevent transplant rejection

UCLA researchers have pinpointed the culprit behind chronic rejection of heart, lung and kidney transplants. Published in the Nov. 23 edition of Science Signaling, their findings suggest new therapeutic approaches for preventing transplant rejection and sabotaging cancer growth.

19 Nov 2010

African Americans have faster rates of decline in kidney function

African Americans along with some groups of Hispanics have faster rates of decline in kidney function compared to white Americans, according to a study presented at the American Society of Nephrology's 43rd Annual Meeting and Scientific Exposition.

19 Nov 2010

Caprini Risk Model helps predict VTE risk in patients undergoing plastic surgery

Patients undergoing plastic or reconstructive surgery should receive a risk assessment before their procedure to predict whether they'll develop potentially fatal blood clots in the legs or lungs, according to research at the University of Michigan Medical School. Researchers also found that 1 in 9 patients at highest risk based on that assessment will develop clots if not given clot-preventing medications after surgery.

19 Nov 2010

Bristol-Myers Squibb, Pfizer discontinue Phase 3 APPRAISE-2 trial in patients with ACS

Bristol-Myers Squibb Company and Pfizer today reported that the companies have discontinued the Phase 3 APPRAISE-2 clinical trial in patients with recent Acute Coronary Syndrome (ACS) treated with apixaban or placebo in addition to mono or dual antiplatelet therapy.

19 Nov 2010

Study suggests pomegranate juice can ward-off complications in kidney disease patients

Studies in recent years have claimed multiple health benefits of pomegranate juice, including that it is a good source of antioxidants and lowers both cholesterol and blood pressure, especially in diabetic and hypertensive patients.

19 Nov 2010

Experts formulate research related to psychological adjustment and traumatic brain injury

Five U.S. federal agencies recently cosponsored a set of expert work groups to formulate common data elements for research related to psychological adjustment and traumatic brain injury (TBI).

19 Nov 2010

Genetic alterations may lead to thoracic aortic disease

19 Nov 2010

GRAVITAS Trial finds high dose of clopidogrel does not reduce risk of ischemic events

Accumetrics, Inc., developer and marketer of the VerifyNow System, today announced that the GRAVITAS (Gauging Responsiveness With A VerifyNow Assay-Impact On Thrombosis And Safety) Trial found that in patients with high residual platelet reactivity, doubling the maintenance dose of clopidogrel did not reduce the risk of further ischemic events after percutaneous coronary intervention (PCI).

19 Nov 2010

Scientists solve receptor structure that responds to neurotransmitter dopamine

A team led by scientists at The Scripps Research Institute has solved the structure of one of the receptors that responds to the neurotransmitter dopamine. Although dopamine transmission is essential to normal brain functioning, the biological assembly of the molecules involved in this crucial neuronal interplay had not been known until now.

19 Nov 2010

Aastrom announces interim analysis of Phase 2b RESTORE-CLI clinical trial for treatment failure

Aastrom Biosciences, Inc., a leading developer of expanded autologous cellular therapies for the treatment of severe cardiovascular diseases, today announced that an interim analysis of all 86 patients enrolled in the company's Phase 2b RESTORE-CLI clinical trial shows that the study achieved both its primary safety endpoint and primary efficacy endpoint of time to first occurrence of treatment failure.

19 Nov 2010

Scientists discover bone matrix plays a vital role in tissue hardening

Scientists are reporting the first direct evidence that a subtle change in the physical properties of a tissue can affect its function. The finding has immediate implications for understanding several rare hearing disorders, they said, and ultimately could offer insight into such conditions as osteoporosis, arthritis, cardiovascular disease and cancer.

19 Nov 2010

St. Jude Medical completes acquisition of AGA Medical

St. Jude Medical, Inc. today announced that it has successfully completed its acquisition of AGA Medical Holdings, Inc.

19 Nov 2010

Heart Disease News and Research

Latest Heart Disease News and Research

Merck wins third FOSAMAX bellwether trial

FDA-approved anti-parasite drug blocks Wnt signaling pathway in colon cancer

Childhood obesity linked to adult metabolic abnormalities and cardiovascular disease

Medtronic's Valiant Stent System effective for thoracic aortic aneurysms treatment

Boston Scientific's CRT-Ds, ICDs receive CE Mark approval

MedStart Summer Enrichment Program helps students better understand medical conditions: Studies

Fifth gene defect, 47 DNA regions linked to thoracic aortic disease: Researchers

Acacia subsidiary receives patents for wireless physiological monitoring technology

Research suggests new therapeutic approach to prevent transplant rejection

African Americans have faster rates of decline in kidney function

Caprini Risk Model helps predict VTE risk in patients undergoing plastic surgery

Bristol-Myers Squibb, Pfizer discontinue Phase 3 APPRAISE-2 trial in patients with ACS

Study suggests pomegranate juice can ward-off complications in kidney disease patients

Experts formulate research related to psychological adjustment and traumatic brain injury

Genetic alterations may lead to thoracic aortic disease

GRAVITAS Trial finds high dose of clopidogrel does not reduce risk of ischemic events

Scientists solve receptor structure that responds to neurotransmitter dopamine

Aastrom announces interim analysis of Phase 2b RESTORE-CLI clinical trial for treatment failure

Scientists discover bone matrix plays a vital role in tissue hardening

St. Jude Medical completes acquisition of AGA Medical

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Heart Disease News and Research

Latest Heart Disease News and Research

Real-time Raman monitoring for pharmaceutical hot melt extrusion

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