Heart Disease News and Research

Latest Heart Disease News and Research

ANTIPAF trial reveals ARBs do not reduce number of AF episodes in paroxysmal AF patients

Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting about 7 million people in Europe. It is a progressive chronic disease in which episodes become more frequent and long-lasting over time. Conventional anti-arrhythmic therapy aims at halting progression and reducing symptoms, but the use of most anti-arrhythmic drugs is compromised by severe side effects, such as pro-arrhythmia or extra-cardiac organ toxicity.

31 Aug 2010

Data monitoring committee recommends early termination following impressive results of AVERROES study

The data monitoring committee of the AVERROES study, seeing overwhelming evidence of the success of apixaban in the prevention of stroke in patients with atrial fibrillation who are unsuitable for the conventional treatment of warfarin, has recommended early termination of this study. The decision came after repeated review and careful consideration of all efficacy and safety data.

31 Aug 2010

Prolonged exercise shows no evidence of cardiac fatigue: Research

In a research project aimed at understanding the effect of prolonged exercise on the heart, the Karolinska Institutet and the Swedish School of Sport and Health Sciences studied a group of competitors taking part in the Adventure Racing World Championship. The results show no evidence of cardiac fatigue despite the fact that this is a continuous endurance event lasting between five and seven days.

31 Aug 2010

Study finds black females exhibit greater magnitude of LVH than their white counterparts

A study conducted in the UK has established the extent of cardiac adaptation amongst female athletes competing in a number of sports.

31 Aug 2010

Running continuously over 50 or 100 miles may not be good for the heart: Study

In 2009, a study was conducted in UK by Liverpool John Moores University and the Countess of Chester Hospital to assess the effects of running in ultra-endurance races. Typically aimed at super-fit and experienced athletes, these races are held over distances exceeding 50 miles (80 kilometres). The conclusions suggest that some damage is likely to occur to the heart muscle of competitors, while 12 percent of the study group showed signs of significant cardiac damage.

31 Aug 2010

Telmisartan and amlodipine combination therapy helps achieve high BP control/response rates

Data show that treatment with a single-pill combination of telmisartan, an angiotensin receptor blocker, (ARB) and amlodipine, a calcium channel blocker (CCB) results in significant reductions in blood pressure (BP) in patients with severe hypertension.

31 Aug 2010

ESC/EACTS releases new Myocardial Revascularisation guidelines

Multivessel and left main disease have been long considered as mainstay indications for coronary artery bypass grafting surgery (CABG). This recommendation, however, has been strongly challenged on several occasions. The release of new Myocardial Revascularisation guidelines by ESC and the European Association of Cardio-Thoracic Surgeons (EACTS) at the ESC Congress on Sunday 29 August is likely to shed new light on what has become a controversial topic.

31 Aug 2010

Phase 3 EINSTEIN-DVT clinical trial data can transform deep vein thrombosis treatment

Johnson & Johnson Pharmaceutical Research & Development, announced today that the investigational, oral anticoagulant rivaroxaban successfully demonstrated non-inferiority compared to the standard of care for the prevention of recurrent venous thromboembolism (VTE) in patients with acute symptomatic deep vein thrombosis (DVT), with a comparable safety profile.

31 Aug 2010

Marathon running does not cause sustained heart damage

A study of 167 amateur runners at the 2006 and 2007 Berlin marathons is lowering concerns that this type of activity leads to sustained heart damage, particularly among older competitors. Marathons are becoming an increasingly popular challenge for amateur runners wanting to test their endurance over the classic 26-mile distance. The medical community, however, has long been concerned about how marathons impact the heart - and it has not yet been shown if the effects vary among different age groups or genders.

31 Aug 2010

Bioheart's MyoCell adult stem cell therapy shows effective for heart failure patients: Study

Bioheart, Inc., The mission of the Cell Therapy Foundation is to improve public health through the support of effective adult stem cell research and education. The Foundation aims to promote basic and applied knowledge, processes and cell therapies.

31 Aug 2010

Study shows statin therapy not associated with cancer

In the largest and most reliable study of its type, the University of Oxford (UK) and the University of Sydney (Australia) have demonstrated that statin therapy is not a cause of increased cancer rates and deaths. The conclusions of this study will reassure the millions of people worldwide who are taking statins to lower cholesterol levels, and clarifies earlier research that had raised concerns of a causal link.

31 Aug 2010

MGH scientists develop new microfluidic tool for accurate isolation of neutrophils

A team led by Massachusetts General Hospital (MGH) scientists has developed a new microfluidic tool for quickly and accurately isolating neutrophils - the most abundant type of white blood cell - from small blood samples, an accomplishment that could provide information essential to better understanding the immune system's response to traumatic injury. The system, described in a Nature Medicine paper that received advance online release, also can be adapted to isolate almost any type of cell.

31 Aug 2010

Increasing trend seen in hospital admissions due to atrial fibrillation

A growing epidemic of the world's most common heart rhythm disorder is resulting in an alarming number of hospital admissions in Australia, according to cardiology researchers.

31 Aug 2010

Research on trypanosomes can open way for African sleeping sickness drug development

Trypanosomes are parasites responsible for many human and animal diseases, primarily in tropical climates. One disease these parasites cause, African sleeping sickness, results from the bite of infected tsetse flies, putting over 60 million Africans at risk in 36 sub-Saharan countries. The recent 1998-2001 sleeping sickness epidemics in South Sudan, Angola, Democratic Republic of Congo and Uganda killed tens of thousands of people and resulted in over a half million infected individuals.

31 Aug 2010

Peripheral arterial disease increases cardiovascular disease risk: Study

Most patients don't suspect a thing, and yet they are seriously ill: hardening of the arteries - peripheral arterial disease PAD - doubles the risk of premature death and serious cardiovascular events such as heart attack and stroke.

31 Aug 2010

Study: IV ibuprofen decreases pain, morphine use in pre and post-operative orthopedic surgery patients

Cumberland Pharmaceuticals Inc. today announced the publication of new data supporting the safety and efficacy of Caldolor® (ibuprofen) Injection in pre and post-operative orthopedic surgery patients. The study, which was published in the August edition of the peer-reviewed journal Pain Medicine, concludes that IV ibuprofen significantly decreased pain and morphine use when compared with placebo.

31 Aug 2010

Genetic profiling to predict treatment benefits of ACE inhibitor therapy for CAD

The advantages of prescribing angiotensin-converting enzyme (ACE) inhibitors for stable coronary artery disease (CAD) may be increased by targeting the therapy to the patients most likely to benefit.Clinical characteristics alone do not allow a reliable identification of these patients, so a research programme was carried out at Erasmus University Medical Centre in Rotterdam to develop a genetic profiling model that predicts the treatment benefits of ACE inhibitors and optimises the recommended therapy.

31 Aug 2010

LESSON I trial provides evidence of benefits of everolimus-eluting stent over sirolimus-eluting stent

Results from the LESSON I trial presented today provide preliminary evidence for the therapeutic benefit of the newer generation everolimus-eluting stent over the previous gold standard, the early generation sirolimus-eluting stent. Moreover, LESSON I provides evidence that the formation of blood clots (stent thrombosis) - the principal shortcoming of early generation drug-eluting stents - may be diminished with the newer generation everolimus-eluting stent.

31 Aug 2010

Using clopidogrel, PPIs increases cardiac damage risk: Study

Patients with coronary artery disease undergoing stent implantation are often prescribed the antiplatelet drug, clopidogrel. This drug prevents blood clots, but is known to have a side-effect that can cause stomach bleeding. Consequently, many users are also prescribed a proton pump inhibitor (PPI). Now, however, a meta-analysis of almost 160,000 patients carried out at the Medical University of Vienna and Wilhelminenhospital, Vienna, has shown that simultaneous use of these drugs can increase the risk of cardiac damage.

31 Aug 2010

Reduced heparin dose lowers bleeding risk after PCI without increasing risk of ischaemic complications

With both bleeding und thrombotic complications having a negative effect on PCI outcomes, increasing efforts have been made to improve PCI anticoagulation regimens. Although unfractionated heparin has been the standard anti-thrombotic agent in interventional cardiology for decades, there is still no solid evidence from large clinical trials to guide its dosing during PCI.

31 Aug 2010

Heart Disease News and Research

Latest Heart Disease News and Research

ANTIPAF trial reveals ARBs do not reduce number of AF episodes in paroxysmal AF patients

Data monitoring committee recommends early termination following impressive results of AVERROES study

Prolonged exercise shows no evidence of cardiac fatigue: Research

Study finds black females exhibit greater magnitude of LVH than their white counterparts

Running continuously over 50 or 100 miles may not be good for the heart: Study

Telmisartan and amlodipine combination therapy helps achieve high BP control/response rates

ESC/EACTS releases new Myocardial Revascularisation guidelines

Phase 3 EINSTEIN-DVT clinical trial data can transform deep vein thrombosis treatment

Marathon running does not cause sustained heart damage

Bioheart's MyoCell adult stem cell therapy shows effective for heart failure patients: Study

Study shows statin therapy not associated with cancer

MGH scientists develop new microfluidic tool for accurate isolation of neutrophils

Increasing trend seen in hospital admissions due to atrial fibrillation

Research on trypanosomes can open way for African sleeping sickness drug development

Peripheral arterial disease increases cardiovascular disease risk: Study

Study: IV ibuprofen decreases pain, morphine use in pre and post-operative orthopedic surgery patients

Genetic profiling to predict treatment benefits of ACE inhibitor therapy for CAD

LESSON I trial provides evidence of benefits of everolimus-eluting stent over sirolimus-eluting stent

Using clopidogrel, PPIs increases cardiac damage risk: Study

Reduced heparin dose lowers bleeding risk after PCI without increasing risk of ischaemic complications

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Heart Disease News and Research

Latest Heart Disease News and Research

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Newsletters you may be interested in