Immunotherapy News and Research

Latest Immunotherapy News and Research

Blood biopsy helps identify targetable genetic alterations in patients with cancer of unknown primary

Using fragments of circulating tumor DNA in blood, University of California San Diego School of Medicine researchers were able to identify theoretically targetable genetic alterations in 66 percent of patients with cancer of unknown primary (CUP), a rare disease with seven to 12 cases per 100,000 people each year.

16 Aug 2017

Alternative medicine use instead of proven cancer therapies results in worse survival

Patients who choose to receive alternative therapy as treatment for curable cancers instead of conventional cancer treatment have a higher risk of death, according to researchers from the Cancer Outcomes, Public Policy and Effectiveness Research Center at Yale School of Medicine and Yale Cancer Center.

11 Aug 2017

Fred Hutch aims to prevent and find cures for cancers caused by infectious agents

Fred Hutchinson Cancer Research Center is launching a new integrated research center to prevent and find cures for cancers caused by infectious agents.

10 Aug 2017

Immunotherapy shows promise in treatment of Type 1 diabetes

Around 1.25 million Americans are living with type 1 diabetes and 40,000 new cases are detected each year. In this condition body’s own immune system attacks and damages the insulin-producing β-cells inside the pancreas leading to impaired glucose metabolism in the body. There is no other treatment for this condition than regular painful insulin injections to maintain the normal insulin levels in the body. Type 1 diabetes is currently considered to be incurable.

10 Aug 2017

Promising brain cancer vaccine developed at Roswell Park receives orphan drug status from FDA

The U.S. Food and Drug Administration has awarded orphan drug status to a promising immunotherapy vaccine developed at Roswell Park Cancer Institute.

8 Aug 2017

Tackling food allergies: is immunotherapy the answer?

Food allergies affect approximately 8% of school children in the United States and the United Kingdom. The highest prevalence of food allergies is in Australia affecting approximately 10% of young children. It is lower in the developing world.

7 Aug 2017

Researchers hope to harness immune cells for better treatment of allergies, infections

By learning how a recently discovered immune cell works in the body, researchers hope to one day harness the cells to better treat allergies and infections, according to new Cornell University research.

4 Aug 2017

Immune ‘hotspots’ could help predict the risk of breast cancer relapse in patients, study finds

Scientists from The Institute of Cancer Research, London has developed a new test through which women at a greater risk of relapsing from breast cancer within 10 years of diagnosis can be identified.

4 Aug 2017

In-depth tumor sequencing reveals key molecular drivers of metastatic cancers

Five hundred cancer patients are getting an in-depth look at their genomes as part of a new clinical study that is revealing some of the key molecular drivers of metastatic cancers.

3 Aug 2017

Researchers deliver knock-out blow to different types of cancer

Targeting healthy cells that have been hijacked by cancer cells could help treat many different types of the disease, according to research funded by Cancer Research UK and published in the Journal of the National Cancer Institute today (Thursday).

3 Aug 2017

Penn researchers discover how DNA damage turns immune cells against cancer

Cancer is essentially a disease of the cell replication cycle. The goal of treating the disease is to permanently kill off the cells that replicate with abandon without any molecular brakes.

31 Jul 2017

Bringing highly potent cell therapy products to market

There are two main challenges and both relate to manufacturing. The first one is to make sure you can manufacture therapies with reasonable costs and the second one is to make sure that you can balance the capacity you need with the demands.

31 Jul 2017

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

A new cooperative research study including Norris Cotton Cancer Center's Lionel Lewis, MB BCh, MD, finds that nivolumab plus ipilimumab therapy demonstrated manageable safety, notable antitumor activity, and durable responses with promising long term overall survival in patients with metastatic renal cell cancer (mRCC).

26 Jul 2017

Molecular classification of gastric cancer subtypes could shape tailored treatment options

Molecular classification of the four distinct subtypes of gastric cancer could potentially shape tailored treatment options by helping to predict survival outcomes and patients' response to chemotherapy.

26 Jul 2017

Research offers explanation for ineffectiveness of checkpoint immunotherapy against bladder cancer

New research offers a possible explanation for why a new type of cancer treatment hasn't been working as expected against bladder cancer.

25 Jul 2017

Researchers discover mechanism that plays key role in development of resistance to immunotherapy

In tumor immunotherapy, the body's own defense system is activated against the tumor cells. However, for the majority of patients, the tumor cells become resistant to the treatments used.

25 Jul 2017

Cellectis wins European patent for CRISPR use in T-cells

Cellectis, a clinical-stage biopharmaceutical company focused on developing immunotherapies based on gene-edited CAR T-cells (UCART), today announced the grant by the European Patent Office of patent No. EP3004337 for the invention of using RNA-guided endonucleases, such as Cas9 or Cpf1 for the genetic engineering of T-cells.

24 Jul 2017

Advanced lung cancer patients get survival benefit with use of concurrent chemotherapy, proton therapy

For patients with advanced, inoperable stage 3 lung cancer, concurrent chemotherapy and the specialized radiation treatment, proton therapy, offers improved survival compared to historical data for standard of care, according to a new study from The University of Texas MD Anderson Cancer Center.

20 Jul 2017

Study: Response to combination immunotherapy in melanoma depends on proportion of immune cells

Whether a melanoma patient will better respond to a single immunotherapy drug or two in combination depends on the abundance of certain white blood cells within their tumors, according to a new study conducted by UC San Francisco researchers joined by physicians from UCSF Health.

20 Jul 2017

Engineered macrophages invade and engulf tumor cells in mouse models

One reason cancer is so difficult to treat is that it avoids detection by the body. Agents of the immune system are constantly checking the surfaces of cells for chemical signals that say they belong, but cancer cells express the same chemical signals as healthy ones.

19 Jul 2017

Immunotherapy News and Research

Latest Immunotherapy News and Research

Blood biopsy helps identify targetable genetic alterations in patients with cancer of unknown primary

Alternative medicine use instead of proven cancer therapies results in worse survival

Fred Hutch aims to prevent and find cures for cancers caused by infectious agents

Immunotherapy shows promise in treatment of Type 1 diabetes

Promising brain cancer vaccine developed at Roswell Park receives orphan drug status from FDA

Tackling food allergies: is immunotherapy the answer?

Researchers hope to harness immune cells for better treatment of allergies, infections

Immune ‘hotspots’ could help predict the risk of breast cancer relapse in patients, study finds

In-depth tumor sequencing reveals key molecular drivers of metastatic cancers

Researchers deliver knock-out blow to different types of cancer

Penn researchers discover how DNA damage turns immune cells against cancer

Bringing highly potent cell therapy products to market

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

Molecular classification of gastric cancer subtypes could shape tailored treatment options

Research offers explanation for ineffectiveness of checkpoint immunotherapy against bladder cancer

Researchers discover mechanism that plays key role in development of resistance to immunotherapy

Cellectis wins European patent for CRISPR use in T-cells

Advanced lung cancer patients get survival benefit with use of concurrent chemotherapy, proton therapy

Study: Response to combination immunotherapy in melanoma depends on proportion of immune cells

Engineered macrophages invade and engulf tumor cells in mouse models

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Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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