Immunotherapy News and Research

Latest Immunotherapy News and Research

New study reveals safety of oral food challenges for detecting food allergies

The best way to find out if someone has a food allergy is through an oral food challenge (OFC) where the person is given a very small dose of the food by mouth under the supervision of a board-certified allergist to test for a severe reaction.

7 Sep 2017

Beta blockers capable of reducing stress signaling may enhance effectiveness of immunotherapy

While the development of therapies designed to block "checkpoints" within the immune system has been one of the most exciting and noteworthy advances in cancer research in recent years, it's also been one of the most puzzling, leaving researchers to ask: Why don't these new therapies work for more patients, and why is their efficacy in controlling cancerous tumors often short-lived? A research team from Roswell Park Cancer Institute has shown that at least one answer - and an excellent opportunity for unleashing the full potential of these promising immunotherapies - may lie in the body's "fight or flight" reaction to stressors and in drugs already widely used to control and temporarily disable this stress response.

31 Aug 2017

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

The U.S. Food and Drug Administration (FDA) has issued a press release making the first even gene therapy available for treatment of children with a form of acute lymphoblastic leukemia (ALL).

30 Aug 2017

$Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL$

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

Novartis announced today that the US Food and Drug Administration has approved Kymriah (tisagenlecleucel) suspension for intravenous infusion, formerly CTL019, the first chimeric antigen receptor T cell (CAR-T) therapy, for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.

30 Aug 2017

FDA approves first cell-based gene therapy for use in the United States

The U.S. Food and Drug Administration issued a historic action today making the first gene therapy available in the United States, ushering in a new approach to the treatment of cancer and other serious and life-threatening diseases.

30 Aug 2017

Researchers develop new approach to efficiently produce versatile antibody therapies

A group of researchers has developed an approach to efficiently produce antibodies that can bind to two different target molecules simultaneously, a long-desired innovation in the field of cancer immunotherapy.

29 Aug 2017

Immunotherapy that uses existing cancer drugs in a new way delivers promising results

Immunotherapy is an emerging field in the global fight against cancer, even though scientists and clinicians have been working for decades to find ways to help the body's immune system detect and attack cancerous cells.

29 Aug 2017

Extensive analysis reveals immune system dynamics after stem cell transplantation in leukemia patients

By combining new system-biological analyses and advanced data analysis, researchers at Karolinska Institutet have been able to monitor the maturation process of the immune system of leukemia patients who have undergone stem cell transplantation.

29 Aug 2017

Review highlights significant progress in developing new biologic drugs to treat colorectal cancer

New biologic drugs, such as monoclonal antibodies and immunotherapies in clinical development, designed to target metastatic colorectal cancer (CRC) and stimulate the immune system to destroy tumor cells are a significant advance in treatment over conventional chemotherapy.

29 Aug 2017

Immune booster could improve effectiveness of vaccines and cancer immunotherapy

Vaccines and cancer immunotherapies do essentially the same thing: They boost a person's immune system, better enabling it to fight an offender, be it microbe or malignancy.

29 Aug 2017

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

Concurrent administration of the T-cell stimulating anti-OX40 antibody and the immune checkpoint inhibitor anti-PD1 antibody attenuated the effect of anti-OX40 and resulted in poor treatment outcomes in mice.

28 Aug 2017

LSU Health New Orleans receives $10 million grant to support research on virus-induced cancers

The National Institute of General Medical Sciences has awarded LSU Health New Orleans a $10 million grant over five years to support new basic research studies advancing the development new diagnostic and therapeutic approaches for virus-induced cancers.

26 Aug 2017

Scientists develop new chimeric antibody to treat malignant cancers in dogs

Scientists have developed a new chimeric antibody that suppresses malignant cancers in dogs, showing promise for safe and effective treatment of intractable cancers.

26 Aug 2017

NIH grant for CWRU professors could enable new directions for cancer immunotherapies

Nicole Steinmetz, PhD, Associate Professor of Biomedical Engineering, Radiology, member of the Case Comprehensive Cancer Center and the Center for RNA Science and Therapeutics in the Division of General Medical Sciences at Case Western Reserve University School of Medicine and the holder of the George J. Picha Designated Professor in Biomaterials, has received a major grant from the National Institutes of Health to help understand how a virus-like particle from plants stimulates potent anti-tumor responses.

26 Aug 2017

Symptoms, triggers of food intolerance found to be similar in animals and humans

People are not the only ones suffering from the symptoms and problems of food intolerance and allergies.

23 Aug 2017

Combination treatment effectively vaccinates mice against cancer

By combining an FDA-approved cancer immunotherapy with an emerging tumor-roasting nanotechnology, Duke University researchers improved the efficacy of both therapies in a proof-of-concept study using mice.

18 Aug 2017

Study provides evidence that oral immunotherapy may be possible cure for peanut allergy

Allergy immunotherapy company Prota Therapeutics Pty Ltd is pleased to announce results from a follow up study of the probiotic and peanut immunotherapy (PPOIT) treatment which it has licensed from the Murdoch Childrens Research Institute, demonstrating long-lasting tolerance effects of treatment more than four years after the original study ended.

18 Aug 2017

Peanut allergy successfully kept at bay with immune-based therapy

Australian researchers from the Murdoch Children’s Research Institute have come up with a latest study results showing that peanut allergy could be treated successfully with an immune-based therapy. This new therapy helped children allergic to peanuts eat these nuts with no reactions for up to four years. The study appeared this week in the journal Lancet Child & Adolescent Health.

17 Aug 2017

Sanford Health launches solid tumor oncolytic virus clinical trial

Sanford Health is the first site in the United States to launch a clinical trial using a genetically-engineered virus that aims to destroy therapy-resistant tumors.

17 Aug 2017

Immunotherapy drug shows favorable safety profile in patients with advanced small cell lung cancer

The immunotherapy drug pembrolizumab has demonstrated a favorable safety profile and "promising durable clinical activity" in pretreated patients who exhibit high levels of the PD-L1 protein in advanced stages of small cell lung cancer (SCLC) – an aggressive form of the disease

16 Aug 2017

Immunotherapy News and Research

Latest Immunotherapy News and Research

New study reveals safety of oral food challenges for detecting food allergies

Beta blockers capable of reducing stress signaling may enhance effectiveness of immunotherapy

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

FDA approves first cell-based gene therapy for use in the United States

Researchers develop new approach to efficiently produce versatile antibody therapies

Immunotherapy that uses existing cancer drugs in a new way delivers promising results

Extensive analysis reveals immune system dynamics after stem cell transplantation in leukemia patients

Review highlights significant progress in developing new biologic drugs to treat colorectal cancer

Immune booster could improve effectiveness of vaccines and cancer immunotherapy

Simultaneous treatment with anti-PD1 and anti-OX40 cancer therapies may have detrimental effect

LSU Health New Orleans receives $10 million grant to support research on virus-induced cancers

Scientists develop new chimeric antibody to treat malignant cancers in dogs

NIH grant for CWRU professors could enable new directions for cancer immunotherapies

Symptoms, triggers of food intolerance found to be similar in animals and humans

Combination treatment effectively vaccinates mice against cancer

Study provides evidence that oral immunotherapy may be possible cure for peanut allergy

Peanut allergy successfully kept at bay with immune-based therapy

Sanford Health launches solid tumor oncolytic virus clinical trial

Immunotherapy drug shows favorable safety profile in patients with advanced small cell lung cancer

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Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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