Immunotherapy News and Research

Latest Immunotherapy News and Research

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells.

15 Dec 2023

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

Colorectal cancer presents with varying clinical characteristics due to tumor heterogeneity. Microsatellite instability (MSI), present in 10%-15% of CRC cases, indicates a different clinical trajectory than microsatellite stable (MSS) patients.

15 Dec 2023

QUT scientists discover promising treatment for fatal endometrial cancer

QUT scientists have discovered a promising new therapy for a deadly type of endometrial cancer that has a poor prognosis if the cancer spreads or returns after initial treatment, a plight that affects 15-20 per cent of endometrial cancer patients.

15 Dec 2023

NIAID study identifies critical T-cell function missing in prior HIV vaccine candidates

An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study from researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and colleagues.

14 Dec 2023

Atezolizumab plus carboplatin: A winning combination for metastatic triple-negative breast cancer

Immunotherapy in combination with chemotherapy has become an important therapeutic treatment option in some patients with metastatic breast cancer.

14 Dec 2023

Researchers develop humanized mouse model for macrophage-targeted cancer immunotherapy

Mice with human immune cells are a new way of testing anti-cancer drugs targeting the immune system in pre-clinical studies.

14 Dec 2023

Advancements in food allergy research promise improved diagnosis and treatment options

A review in the Journal of Allergy and Clinical Immunology discusses the global trends in food allergy prevalence, with stabilization in developed regions and an increase in developing countries, alongside advancements in understanding the mechanisms, diagnosis, and treatment of food allergies.

13 Dec 2023

Simple trick supercharges T cells to fight stubborn solid tumors

Wistar researchers successfully tested a simple intervention that could unlock greater anti-tumor power in therapies that use T cells - an approach known as "cell-based therapy," which uses specially designed T cells to fight cancer.

13 Dec 2023

Climate change and the future of allergic disease management

As we head into the new year, some issues may be coming into sharper focus for those involved in allergy-immunology issues.

13 Dec 2023

Weill Cornell Medicine joins PICI network for collaborative cancer research effort

The Parker Institute for Cancer Immunotherapy (PICI), the largest concentration of immuno-oncology (IO) expertise in the world, announced it has added Weill Cornell Medicine to its network of preeminent academic and medical research institutions at the forefront of the fight against cancer.

13 Dec 2023

Developing a virtual twin for personalized cancer treatment with CAR-T cell therapy

In recent years, cancer immunotherapies have established themselves as a further pillar of medical oncology alongside traditional treatment options (surgery, radiotherapy and chemotherapy).

13 Dec 2023

Liquid biopsy may offer new tools for personalized immunotherapy in lung cancer

Using a "liquid biopsy" to study genetic material from tumors shed into the bloodstream together with immune cells could help clinicians predict which patients with advanced lung cancers are responding to immunotherapies and which patients may develop immune-related side effects several months later, according to research directed by investigators at the Johns Hopkins Kimmel Cancer Center, the Bloomberg~Kimmel Institute for Cancer Immunotherapy and Allegheny Health Network Cancer Institute in Pittsburgh.

12 Dec 2023

New study unlocks hope for immunotherapy in metastatic prostate cancer

Immunotherapy has been disappointing as a prostate cancer treatment, but a new Columbia study suggests that the powerful treatments have potential when the disease starts to spread.

12 Dec 2023

New combination treatment offers hope for older patients with mantle cell lymphoma

The phase 2 trial PrE0405 met its primary endpoint, achieving a complete response (CR) rate of 85% in 33 patients over the age of 60 with mantle cell lymphoma (MCL) who received bendamustine and rituximab, a standard chemo-immunotherapy treatment, along with venetoclax, which is investigational in this setting.

11 Dec 2023

Double punch for B-cell lymphomas: CAR T-cell innovation boosts efficacy, cuts toxicity

The Malaghan Institute of Medical Research in collaboration with Wellington Zhaotai Therapies Limited today announced results of its phase 1 dose escalation trial of a new third-generation anti-CD19 chimeric antigen receptor (CAR) T-cell therapy to be presented at the American Society of Hematology (ASH) Annual Meeting in San Diego on 11 December, 3pm.

11 Dec 2023

Personalized treatment for leukemia results in longer life and fewer side effects

Personalized treatment for the most common form of adult leukemia helps patients survive for longer and stay in remission, a phase III trial has found.

11 Dec 2023

New combinations and targeted therapies for acute myeloid leukemia on the horizon

The treatment landscape for acute myeloid leukemia (AML) is evolving rapidly, as research discoveries at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and other academic cancer centers advance new, more effective therapies for this aggressive blood cancer.

11 Dec 2023

CAR-T cell therapy remains viable for patients in lymphoma remission, study finds

A study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests that CAR-T immunotherapy remains a viable option for patients who have lymphoma that goes into remission before the cell therapy begins.

11 Dec 2023

Combination of dasatinib and blinatumomab offers effective treatment for older Ph+ ALL patients

Older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who were not good candidates for the standard treatment of intensive chemotherapy had a median overall survival (OS) of 6.5 years on an alternate regimen of dasatinib and blinatumomab.

11 Dec 2023

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Study explores immunoregulatory nanomedicines for respiratory infections, highlighting their potential in enhancing treatment outcomes and vaccine efficacy.

7 Dec 2023

Immunotherapy News and Research

Latest Immunotherapy News and Research

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

QUT scientists discover promising treatment for fatal endometrial cancer

NIAID study identifies critical T-cell function missing in prior HIV vaccine candidates

Atezolizumab plus carboplatin: A winning combination for metastatic triple-negative breast cancer

Researchers develop humanized mouse model for macrophage-targeted cancer immunotherapy

Advancements in food allergy research promise improved diagnosis and treatment options

Simple trick supercharges T cells to fight stubborn solid tumors

Climate change and the future of allergic disease management

Weill Cornell Medicine joins PICI network for collaborative cancer research effort

Developing a virtual twin for personalized cancer treatment with CAR-T cell therapy

Liquid biopsy may offer new tools for personalized immunotherapy in lung cancer

New study unlocks hope for immunotherapy in metastatic prostate cancer

New combination treatment offers hope for older patients with mantle cell lymphoma

Double punch for B-cell lymphomas: CAR T-cell innovation boosts efficacy, cuts toxicity

Personalized treatment for leukemia results in longer life and fewer side effects

New combinations and targeted therapies for acute myeloid leukemia on the horizon

CAR-T cell therapy remains viable for patients in lymphoma remission, study finds

Combination of dasatinib and blinatumomab offers effective treatment for older Ph+ ALL patients

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Event guide: 7th Allogeneic Cell Therapies Summit eBook

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Immunotherapy News and Research

Latest Immunotherapy News and Research

Event guide: 7th Allogeneic Cell Therapies Summit eBook

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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