Inflammatory Bowel Disease News and Research

Latest Inflammatory Bowel Disease News and Research

IL-25 both promotes and limits inflammatory diseases

The same signal responsible for promoting the type of immune responses that cause asthma and allergy can also limit the type of inflammation associated with debilitating diseases like inflammatory bowel disease, arthritis and multiple sclerosis, according to researchers from the University of Pennsylvania School of Veterinary Medicine.

13 Apr 2006

MIT look at how cells make life-or-death decisions

The biological processes underlying diseases such as rheumatoid arthritis and cancer are fundamentally linked, and should be linked in how they are treated with drugs, a series of MIT studies indicates.

6 Apr 2006

Data from Novogen inflammatory bowel disease drug Phase I clinical trial shows promise

A recently completed Phase 1 clinical trial of an investigational drug to treat inflammatory bowel disease has demonstrated rapid absorption indicating potential for development as an oral therapy.

6 Mar 2006

Drugs formerly contraindicated for inflammatory bowel disease prove beneficial for pain relief

According to two studies published in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, prescription painkillers are effective in easing the pain of patients with dormant inflammatory bowel disease (IBD) and are not likely to cause symptom flare-ups in IBD patients in remissions

12 Feb 2006

CT enteroclysis should replace conventional enteroclysis in patients with Crohn's disease

The diagnostic value of CT enteroclysis is superior to conventional enteroclysis, previously considered the gold standard, as an imaging method for the evaluation of the small bowel in patients with Crohn's disease, a new study shows.

7 Feb 2006

Eosinophilic esophagitis gene discovery

Researchers at Cincinnati Children's Hospital Medical Center have discovered the first gene associated with eosinophilic esophagitis, one of a number of eosinophil-related diseases in which the body produces abnormally large amounts of white blood cells that can lead to allergy related illnesses.

7 Feb 2006

New biochip predicts evolution of inflammatory bowel disease

The treatment of inflammatory bowel disease, which includes Crohn's disease and ulcerative colitis, has very high costs and can include admissions and surgical interventions. Until now, there was no precise tools to predict the evolution and prognosis of these diseases.

26 Jan 2006

UCLA examines disease-versus-disease interactions

The knowledge that one disease may prevent the onset of another is not new. For example, the discovery that cowpox vaccines can prevent smallpox dates back to 1798.

5 Jan 2006

Researchers shed light on a key molecular switch in T helper cells

Defects in immune system cells called T helper cells may lead to diseases characterized by a faulty inflammatory response such as autoimmunity and asthma. Understanding the molecular steps involved in how T helper cells mature may help researchers develop treatments for these diseases.

17 Oct 2005

Gut antibody could prove to be a promising drug target for Crohn's disease

A collaboration led by the Burnham Institute for Medical Research has found that an antibody which binds to an unusual sugar molecule residing in the gut halts the inflammation seen in Crohn's disease and other intestinal inflammations. The antibody could prove to be a promising drug target for these common chronic intestinal disorders.

9 Oct 2005

Gaps in the intestinal barrier could be a cause of inflammatory diseases of the gut such as Crohn's Disease

Their research, led by Professor Alastair Watson in the University's Faculty of Medicine, could have important implications for the treatment of patients with diseases like Crohn's - an inflammatory bowel disorder that causes severe ulceration in the intestine, leading to pain, bleeding and diarrhoea.

20 Sep 2005

Parasite could help prevent asthma

Asthma in Britain has reached epidemic proportions and the country now has one of the highest numbers of sufferers of the allergy in the world; in Ireland alone it is reported that as many as 30% of all schoolchildren have symptoms of the disease.

5 Sep 2005

Hundreds of identified genes involved in the pathophysiology of ulcerative colitis and Crohn disease

In a paper published in PLoS Medicine researchers from the German Genome Research Network have analysed the expression of thousands of genes from patients with inflammatory bowel disease (ulcerative colitis and Crohn disease) using a genome wide approach to produce a comprehensive picture of which genes are activated in these conditions.

24 Aug 2005

Potential new target for cannabis-derived drugs as a treatment of inflammatory bowel disease

Researchers investigating anecdotal evidence that cannabis relieves some of the symptoms of inflammatory bowel disease (IBD) have discovered a potential new target for cannabis-derived drugs for treatment of the disease.

2 Aug 2005

Cannabis drugs may benefit those with bowel disease

UK scientists say they believe that patients with inflammatory bowel disease may benefit from cannabis-based drugs.

1 Aug 2005

Pseudomonas aeruginosa has broken the immune system's code

The human opportunistic pathogen, Pseudomonas aeruginosa, has broken the immune system's code, report researchers from the University of Chicago, enabling the bacteria to recognize when its host is most vulnerable and to launch an attack before the weakened host can muster its defenses.

1 Aug 2005