Inflammatory Bowel Disease News and Research

Latest Inflammatory Bowel Disease News and Research

Efficacy of Guanilib confirmed for inflammatory bowel disease

Callisto Pharmaceuticals has announced additional data confirming efficacy of Guanilib, a first-in-class compound currently being developed for the treatment of inflammatory bowel disease (IBD), in two different standard animal models of experimental colitis.

7 Apr 2007

Common questions about irritable bowel syndrome

Will adding fiber to my diet bring relief? Are dairy products really off limits? Is there a way to actually diagnose what I have, or is it all in my head?

4 Apr 2007

Scientists decipher a signaling pathway crucially involved in Crohn's disease and ulcerative colitis

Inflammatory bowel diseases, such as Crohn's disease and Ulcerative Colitis, severely impair the lives of more than four million people worldwide. The development of effective therapies against these diseases requires an understanding of their underlying molecular mechanisms.

15 Mar 2007

New combined laparoscopy and colonoscopy procedure at NYPH/Weill Cornell

A small number of patients diagnosed with polyps in their large intestine have extensive or difficult-to-remove polyps, such as those that are flattened against the colon wall or in hard-to-reach places. As with all polyps that may develop into malignant cancers, they must be removed.

4 Mar 2007

FDA approves Humira (adalimumab) for Crohn's disease

The U.S. Food and Drug Administration (FDA) today approved Humira (adalimumab) to treat adult patients with moderately to severely active Crohn's disease, a chronic inflammatory disease of the intestines, which affects an estimated one million Americans.

27 Feb 2007

Turmeric for prevention of rheumatoid arthritis and osteoporosis

An ancient spice, long used in traditional Asian medicine, may hold promise for the prevention of both rheumatoid arthritis and osteoporosis, according to a recently completed study at The University of Arizona College of Medicine.

30 Oct 2006

Compliance with medications lowers health care costs

Patients with inflammatory bowel disease (IBD) who take medications as directed have decreased medical costs, researchers from the University of Chicago researchers report at the American College of Gastroenterology annual scientific meeting in Las Vegas. A second study from the same group, however, suggests that there is no simple way to improve compliance.

23 Oct 2006

Researchers create roadmap to integrin activation

Calling it an important technical advance in the study of the complex receptors and pathways of the body's cellular system, researchers at the University of California, San Diego (UCSD) School of Medicine have reconstructed the signaling pathways that impact activation of a receptor that is critical to the control of bleeding and to the thrombosis that occurs in heart attacks and strokes.

18 Sep 2006

Quality indicators for gastrointestinal endoscopic procedures

Defining measurements and identifying quality standards in the delivery of colonoscopic care is a major priority for the nation's leading gastrointestinal endoscopic healthcare association.

13 Sep 2006

Enrichment of regulatory CD4+CD25+ T cells by inhibition of phospholipase D signaling

A signaling molecule with an affinity for alcohol has yielded a rapid, inexpensive way to make large numbers of immune cells that work like beat cops keeping misguided cells from attacking the body.

8 Aug 2006

Crohn's disease - possible genetic cause found

Patients with Crohn's disease of the colon have one copy less than healthy persons of the beta-defensin 2 gene, a gene coding for an important defense molecule of the body.

17 Jul 2006

Do guidelines for the treatment of osteoporosis in patients with inflammatory bowel disease (IBD) matter?

A new study in the American Journal of Gastroenterology examined the recently set Guidelines regarding the treatment and management of osteoporosis in patients with Inflammatory Bowel Disease (IBD), and found that they are effective.

10 Jul 2006

Importance of T cells in the prevention of autoimmune diseases

Centenary scientist Associate Professor Barbara Fazekas de St. Groth, a leader in inflammatory bowel disease research, has demonstrated for the first time the important role of T cells in the prevention of autoimmune diseases in humans.

9 Jul 2006

Major intestinal surgery may boost the chances of subsequent vitamin A deficiency

Major intestinal surgery, including stomach reduction for obesity, may boost the chances of subsequent vitamin A deficiency, suggests a small study published in the British Journal of Ophthalmology.

14 Jun 2006

Microbes could represent the future of medicine

Not all bacteria are bad. In fact, beneficial microbes could represent the future of medicine, with the potential to treat a variety of diseases in humans and animals from diarrhea and eczema to gum disease and autoimmune disorders.

9 Jun 2006

Humans are a cocktail of bacteria and human cells

Gene experts after studying the DNA of hundreds of different kinds of bacteria in the human gut have reached the conclusion that the human race may not be quite as human as we may think.

4 Jun 2006

Gene variation linked to more severe Crohn's disease

Building on previous evidence supporting the theory that the pathophysiology of Crohn's Disease is altered by genetic variation, recent studies have found that the combination of immune signals given by three variants of a single candidate gene affects the severity of the disease.

1 Jun 2006

Study reveals how production of interferon gamma is controlled in natural killer cells

A new study reveals how the production of a potent immune regulator called interferon gamma (IFNg) is controlled in natural killer (NK) cells, immune cells that typically defend the body against cancer and infections.

31 May 2006

Stem cell 'fusion' occurs in tumors

An Oregon Health & Science University study is adding credence to an increasingly popular theory that fusion is what bonds stem cells with bone marrow cells to regenerate organ tissue.

10 May 2006

IL-25 both promotes and limits inflammatory diseases

The same signal responsible for promoting the type of immune responses that cause asthma and allergy can also limit the type of inflammation associated with debilitating diseases like inflammatory bowel disease, arthritis and multiple sclerosis, according to researchers from the University of Pennsylvania School of Veterinary Medicine.

13 Apr 2006