Metabolism News and Research

Latest Metabolism News and Research

Researchers discover new link between diet, intestinal stem cells and disease

The intestine is essential for maintaining our energy balance and is a master at reacting quickly to changes in nutrition and nutrient balance.

21 Nov 2021

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic disorder affecting children and adolescents, suggests a study in mice by scientists at the National Institutes of Health.

20 Nov 2021

Short-term severe calorie restriction safe, feasible, and well tolerated by cancer patients

A diet involving short-term, severe calorie restriction was safe, feasible, and resulted in a decrease of blood glucose and growth factor concentration, reduction in peripheral blood immunosuppressive cells, and enhanced intratumor T-cell infiltration in cancer patients receiving standard-of-care therapy, according to the results of a clinical trial.

18 Nov 2021

Northwestern awarded grant to advance equity in biomedical sciences

Northwestern University Feinberg School of Medicine has been awarded a grant from the Walder Foundation via the COVID-19 Fund to Retain Clinical Scientists (FRCS) competition, designed to support policies and practices at U.S. medical schools to advance research productivity and retain early-career clinician investigators experiencing family caregiving challenges due to the COVID-19 pandemic.

17 Nov 2021

Study may help predict genomic changes that may happen in advanced cancers based on therapy

A novel way to look at cancer treatment resistance offers the possibility for identifying genetic mechanisms involved and alternative treatment approaches.

17 Nov 2021

Scientists predict structures of eukaryotic protein complexes using AI

UT Southwestern and University of Washington researchers led an international team that used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions.

17 Nov 2021

Model simulations show no need for DEX dose adjustments in COVID-19 patients with liver disease

A recent study sed PBPK modeling to demonstrate the use of DEX PKs for the treatment of COVID-19 in patients with liver impairment.

17 Nov 2021

Scientists identify new gene that contributes to type 1 diabetes progression

When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.

16 Nov 2021

Scientists develop a promising new approach to potentially treat Alzheimer's disease

A promising new approach to potentially treat Alzheimer's disease – and also vaccinate against it – has been developed by a team of UK and German scientists.

15 Nov 2021

Study analyzes the health effects of a patented DGA compound

A study conducted at the University of Jyväskylä analyzed the health effects of a patented DGA compound and compared them to the effects of exercise.

15 Nov 2021

Racial or ethnic group of patients with diabetes influences prognosis of the disease

Professor and researcher of the Faculty of Nursing and Podiatry of the UV, Yasmín Ezzatvar, together with researchers from other centers, concludes that the racial or ethnic group of patients with type 1 and 2 diabetes mellitus influences the prognosis of the disease, due to differences in mortality, risk of kidney disease or risk of cardiovascular disease.

15 Nov 2021

Study finds beneficial and harmful short-term health effects of caffeinated coffee consumption

Drinking caffeinated coffee appears to have both beneficial and harmful short-term health effects: increased abnormal heartbeats, increased physical activity and reduced sleep duration, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2021.

15 Nov 2021

Expert to focus on the wonder of hormones that control energy balance and metabolism

An exploration of the beauty and wonder of the hormones that control our energy balance and metabolism and how they can be replaced and manipulated to improve human health will be the focus of a lecture celebrating the centenary of insulin by Professor Sir Stephen O'Rahilly at the Royal Society of Medicine on Thursday 2 December 2021.

15 Nov 2021

Inflammatory chemicals involved in fat metabolism play key role in ALS, study shows

A new study using genetically engineered mice and human cell and tissue samples has added to evidence that higher levels of inflammatory chemicals involved in fat metabolism occur in people with amyotrophic lateral sclerosis (ALS), the neuromuscular disorder, also known as Lou Gehrig's disease.

15 Nov 2021

Potential therapeutic targets of hydrogen for treatment of the COVID-19

A recent article provided a review of a study led by academician Zhong Nanshan, in China, on COVID-19 treatment by inhalation of a mixed gas composed of hydrogen and oxygen.

12 Nov 2021

Reduced levels of coenzyme A may exacerbate cardiac dysfunction during heart failure

Reduced levels of coenzyme A (CoA) worsen heart failure and likely help exacerbate cardiac dysfunction during heart failure, according to a new study.

11 Nov 2021

Protein in the blood could predict type 2 diabetes many years before diagnosis

A large study led by Lund University in Sweden has identified a protein in the blood that could predict type 2 diabetes up to nineteen years before the onset of the disease.

11 Nov 2021

Identifying an important protein for motor coordination

News-Medical speaks to Professor Jorge Ruas about how he has identified an important protein involved in motor coordination.

10 Nov 2021

BioIVT to highlight the use of SCHH model to investigate drug-drug interaction of bempedoic acid

BioIVT, a leading provider of research models and services for drug and diagnostic development, is hosting a webinar in which researchers will discuss how they used a sandwich-cultured human hepatocyte (SCHH) model to investigate the drug-drug interaction (DDI) potential of bempedoic acid, a drug that was recently approved to treat hypercholesterolemia.

9 Nov 2021

Radiation therapy puts childhood cancer survivors at higher risk of cardiometabolic disease

Decades after battling childhood cancer, survivors often face a new challenge: cardiometabolic disease. A spectrum of conditions that includes coronary heart disease and diabetes, cardiometabolic disease typically impacts people who are obese, elderly, or insulin resistant.

9 Nov 2021

Metabolism News and Research

Latest Metabolism News and Research

Researchers discover new link between diet, intestinal stem cells and disease

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Short-term severe calorie restriction safe, feasible, and well tolerated by cancer patients

Northwestern awarded grant to advance equity in biomedical sciences

Study may help predict genomic changes that may happen in advanced cancers based on therapy

Scientists predict structures of eukaryotic protein complexes using AI

Model simulations show no need for DEX dose adjustments in COVID-19 patients with liver disease

Scientists identify new gene that contributes to type 1 diabetes progression

Scientists develop a promising new approach to potentially treat Alzheimer's disease

Study analyzes the health effects of a patented DGA compound

Racial or ethnic group of patients with diabetes influences prognosis of the disease

Study finds beneficial and harmful short-term health effects of caffeinated coffee consumption

Expert to focus on the wonder of hormones that control energy balance and metabolism

Inflammatory chemicals involved in fat metabolism play key role in ALS, study shows

Potential therapeutic targets of hydrogen for treatment of the COVID-19

Reduced levels of coenzyme A may exacerbate cardiac dysfunction during heart failure

Protein in the blood could predict type 2 diabetes many years before diagnosis

Identifying an important protein for motor coordination

BioIVT to highlight the use of SCHH model to investigate drug-drug interaction of bempedoic acid

Radiation therapy puts childhood cancer survivors at higher risk of cardiometabolic disease

Pharmaceutical Manufacturing - Industry Focus eBook eBook

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering