Metabolism News and Research

Latest Metabolism News and Research

New potato processing technique slows starch digestion to avoid blood sugar spikes

Researchers announced early tests of a new potato processing technique designed to make our bodies digest potato starch more slowly.

14 Jun 2022

Most U.S. adults lack an accurate understanding of the healthfulness of their diet

How healthy is your diet? It seems like a simple question, but according to a new study, it's one that most Americans struggle to get right.

14 Jun 2022

Five new studies shed light on the eating behaviors and diets of teens, young adults

The developmental changes and growing independence that characterize adolescence and young adulthood can make these stages of life both exciting and challenging.

14 Jun 2022

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

Researchers from the Department of Pathology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) have identified a new metabolic mechanism in liver cancer cells, by which macropinocytosis, an endocytic process, is used to engulf extracellular proteins as fuels to support the unlimited growth of hepatocellular carcinoma (HCC) in hypoxia (oxygen deprivation).

14 Jun 2022

Researchers demonstrate the feasibility of pancreatic beta-cell, target-specific CAR-Treg treatment for T1D

Researchers have successfully treated type 1 diabetes in mice using pancreatic beta-cell, target-specific, chimeric antigen-receptor (CAR) regulatory T cells (Tregs), and demonstrated the feasibility of their approach to treat the human condition according to data being presented Monday, June 13 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

'Forever chemicals' associated with greater risk of high blood pressure in middle-aged women

Middle-aged women with higher blood concentrations of common synthetic chemicals called per- and polyfluoroalkyl substances (PFAS), also called "forever chemicals" and found in water, soil, air and food, were at greater risk of developing high blood pressure, compared to their peers who had lower levels of these substances, according to new research published today in Hypertension, an American Heart Association journal.

13 Jun 2022

Scientists find new link between high-fat, high-fructose diets and Type 2 diabetes mellitus

Those who are habitually inclined to consume burgers, fries and soda may think twice about their dietary choices following scientists' latest findings about high-fat, high-fructose diets.

10 Jun 2022

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.

10 Jun 2022

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

A drug used to target IDH1 mutations in select cancers also appears to inhibit the wild-type form of the enzyme, under certain conditions.

9 Jun 2022

First-in-class, anti-cancer mitochondrial drug found to be effective against most carcinoma cell lines

A study of the lead agent (CPI-613) in a class of anticancer drugs undergoing Food and Drug Administration (FDA) approved clinical trials reveals that CPI-613 is effective against most carcinoma cell lines, and, used in combination, could have efficacy against reducing some tumors.

9 Jun 2022

Targeting fatty acid metabolism holds promise for Parkinson's disease

The human brain is lipid rich. Lipids and fatty acids contribute to many important cellular processes. Alpha-synuclein - a protein that plays a critical role in Parkinson's disease (PD) - is known to interact with and alter the balance of lipids and fatty acids.

9 Jun 2022

Research explores effects of iron status on risk of sepsis and severe COVID-19

In a recent article posted to the medRxiv* preprint server, investigators demonstrated a link between high iron status and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)- and sepsis-linked hospitalizations.

7 Jun 2022

Ketogenic diet promotes muscle stem cell resilience but slows injury repair in mice

Fasting sends muscle stem cells into a deep resting state that slows muscle repair but also makes them more resistant to stress, according to a Stanford Medicine study of laboratory mice.

7 Jun 2022

Experts weigh evidence for and against incorporating ultra-processed foods into dietary guidelines

Dietary guidelines form the basis for nutrition advice and regulations around the world. While there is strong scientific consensus around most existing guidelines, one question has recently stirred debate: Should consumers be warned to avoid ultra-processed foods?

7 Jun 2022

Discovery may lead to new treatments to reduce inflammation in vitiligo disease

A new study, led by researchers from the University of California, Irvine, reveals the unique cell-to-cell communication networks that can perpetuate inflammation and prevent repigmentation in patients with vitiligo disease.

7 Jun 2022

Profound neuroinflammation associated with long COVID

Around 36 to 53% of coronavirus disease 2019 (COVID-19) patients develop persistent chronic symptoms, often referred to as long COVID or PASC.

7 Jun 2022

Etiologies of liver cancer are changing and the prognosis is mixed, study says

The primary causes of liver cancer are well known: viral (hepatitis B and C), alcohol and non-alcoholic steatohepatitis (NASH), a condition in which fat builds up in the liver, resulting in chronic inflammation and damage.

7 Jun 2022

Substances touted to improve athletic performance and high fat diet fuel pancreatic cancer’s development

Researchers at the University of Michigan Rogel Cancer Center have found a cell nuclear receptor activated by high fat diets and synthetic substances in unregulated athletic performance enhancers fuels the progression of precancerous pancreas lesions into pancreatic cancer.

1 Jun 2022

UCI-led study identifies sex-specific circuits of muscle signaling to other tissues

A new University of California, Irvine-led study identifies sex-specific circuits of muscle signaling to other tissues and that the organs and processes muscle impacts are markedly different between males and females.

31 May 2022

Liver4Life research team treated damaged liver in a machine and then implanted the recovered organ

The multidisciplinary Zurich research team Liver4Life has succeeded in doing something during a treatment attempt that had never been achieved in the history of medicine until now: it treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.

31 May 2022

Metabolism News and Research

Latest Metabolism News and Research

New potato processing technique slows starch digestion to avoid blood sugar spikes

Most U.S. adults lack an accurate understanding of the healthfulness of their diet

Five new studies shed light on the eating behaviors and diets of teens, young adults

Targeting macropinocytosis may be an effective therapeutic approach for hepatocellular carcinoma

Researchers demonstrate the feasibility of pancreatic beta-cell, target-specific CAR-Treg treatment for T1D

'Forever chemicals' associated with greater risk of high blood pressure in middle-aged women

Scientists find new link between high-fat, high-fructose diets and Type 2 diabetes mellitus

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

First-in-class, anti-cancer mitochondrial drug found to be effective against most carcinoma cell lines

Targeting fatty acid metabolism holds promise for Parkinson's disease

Research explores effects of iron status on risk of sepsis and severe COVID-19

Ketogenic diet promotes muscle stem cell resilience but slows injury repair in mice

Experts weigh evidence for and against incorporating ultra-processed foods into dietary guidelines

Discovery may lead to new treatments to reduce inflammation in vitiligo disease

Profound neuroinflammation associated with long COVID

Etiologies of liver cancer are changing and the prognosis is mixed, study says

Substances touted to improve athletic performance and high fat diet fuel pancreatic cancer’s development

UCI-led study identifies sex-specific circuits of muscle signaling to other tissues

Liver4Life research team treated damaged liver in a machine and then implanted the recovered organ

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging