Metabolism News and Research

Latest Metabolism News and Research

Dietary fiber promotes beneficial conversion of tryptophan by gut bacteria

We get healthy dietary fibres from consuming fruits, vegetables, and whole grains. But why are the fibres so good for us? A team of researchers has discovered that dietary fibres play a crucial role in determining the balance between the production of healthy and harmful substances by influencing the behavior of bacteria in the colon.

26 Jun 2024

Study provides resource for investigating diabetes-linked transcription factors

Scientists have generated a comprehensive map of the gene targets regulated by the transcription factors HNF4A and HNF1A in human pancreatic beta cells and liver cells. Published in the journal Nature Communications, the study revealed common and tissue-specific molecular pathways regulated by HNF4A and HNF1A, two proteins that possess important functions governing the development and function of the pancreas and liver.

26 Jun 2024

Innovative insulin algorithm enhances glucose control for hospitalized patients

Hospitalized patients with complex dietary restrictions often develop hyperglycemia, or high blood sugar.

25 Jun 2024

Study reveals brain health benefits of intermittent fasting and healthy diet plans

Researchers from Johns Hopkins Medicine and the National Institutes of Health's National Institute on Aging say their study of 40 older adults with obesity and insulin resistance who were randomly assigned to either an intermittent fasting diet or a standard healthy diet approved by the U.S. Department of Agriculture (USDA) offers important clues about the potential benefits of both eating plans on brain health.

25 Jun 2024

Novel genetic predisposition to being overweight or obese identified

Researchers performed a case-control study to compare metabolic changes between individuals homozygous for a loss-of-function genetic variation in small integral membrane protein 1 (SMIM1) and the general population.

25 Jun 2024

Research shows gut bacteria's role in mental resilience and reduced anxiety

Researchers characterized brain-gut microbiome (BGM) patterns related to stress resilience.

25 Jun 2024

MicroRNAs shed light on aggressive youthful type 2 diabetes

Type 2 diabetes in young people ages 10 to19 has more than doubled in the past 20 years, yet it remains difficult for physicians to predict who will be diagnosed and who will improve with treatment. A newly published study from the University of Oklahoma shows that measuring the circulating abundance of microRNAs – which affect insulin-producing beta cells in the pancreas – is likely as effective as measuring the level of sugar in the blood for determining how a young person with the condition will fare.

25 Jun 2024

Using microbial community-scale metabolic modeling approach for precision nutrition

Short-chain fatty acids (SCFAs) are beneficial molecules created by the bacteria residing in our gut that are closely tied to improved host metabolism, lower systemic inflammation, better cardiovascular health, lower cancer risk, and more.

24 Jun 2024

Scientists identify potential driver of aggressive lung cancer in patients living in violent neighborhoods

Scientists have identified a potential driver of aggressive lung cancer tumors in patients who live in areas with high levels of violent crime.

24 Jun 2024

Targeting the gut microbiome: A new approach to treating diabetes

Researchers review the role of gut microbiota in the pathogenesis and management of diabetes mellitus.

24 Jun 2024

Will it soon be possible for doctors to use AI to detect and diagnose cancer?

Researchers developed binary and multiclass machine learning models to distinguish cancer from non-cancerous tissue samples.

24 Jun 2024

Vitamin D for carpal tunnel syndrome symptoms

Study examines the impact of vitamin D supplementation on carpal tunnel syndrome (CTS) patients with low vitamin D levels, finding that it improves pain relief and symptom severity when added to corticosteroid therapy.

23 Jun 2024

Nutritious diet may protect against type 2 diabetes, regardless of genetics

A healthy diet that adheres to nutrition recommendations is associated with better blood glucose levels and a lower risk of prediabetes and type 2 diabetes, a new study from the University of Eastern Finland shows. This association was observed also in individuals with a high genetic predisposition to type 2 diabetes.

22 Jun 2024

UT Health San Antonio researcher wins NIH grant to investigate alcohol-associated liver disease

Liver transplants associated with alcohol-related disease are growing at a rapid pace, shifting research to address pathologies behind the ailments in light of a limited supply of organ donors.

21 Jun 2024

How random gene activity shapes lifespan in C. elegans

Why do some people live for longer than others? The genes in our DNA sequence are important, helping avoid disease or maintain general health, but differences in our genome sequence alone explain less than 30% of the natural variance of human life expectancy.

21 Jun 2024

Insilico Medicine leadership team shares insights on AI-powered healthcare innovation

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, announces that the co-CEOs of the company – Alex Zhavoronkov, PhD, and Feng Ren, PhD – will be attending the 15th Annual Meeting of the New Champions, also known as Summer Davos hosted by the World Economic Forum, in Dalian, China, from 25 to 27 June 2024.

21 Jun 2024

Bariatric surgery lowers heart risks and death rates in obese patients with sleep apnea

A Cleveland Clinic study shows that bariatric surgery performed in patients with obesity and moderate to severe obstructive sleep apnea is associated with a significantly lower risk of death and major adverse cardiovascular events, compared with patients who did not have the surgery.

21 Jun 2024

Metabolism News and Research

Latest Metabolism News and Research

Dietary fiber promotes beneficial conversion of tryptophan by gut bacteria

Study provides resource for investigating diabetes-linked transcription factors

Innovative insulin algorithm enhances glucose control for hospitalized patients

Study reveals brain health benefits of intermittent fasting and healthy diet plans

Novel genetic predisposition to being overweight or obese identified

Research shows gut bacteria's role in mental resilience and reduced anxiety

MicroRNAs shed light on aggressive youthful type 2 diabetes

Using microbial community-scale metabolic modeling approach for precision nutrition

Scientists identify potential driver of aggressive lung cancer in patients living in violent neighborhoods

Targeting the gut microbiome: A new approach to treating diabetes

Will it soon be possible for doctors to use AI to detect and diagnose cancer?

Vitamin D for carpal tunnel syndrome symptoms

Nutritious diet may protect against type 2 diabetes, regardless of genetics

UT Health San Antonio researcher wins NIH grant to investigate alcohol-associated liver disease

How random gene activity shapes lifespan in C. elegans

Insilico Medicine leadership team shares insights on AI-powered healthcare innovation

Bariatric surgery lowers heart risks and death rates in obese patients with sleep apnea

Artificial variants of Withanolides act highly specifically against leukemia cells

Role of SMIM1 gene in obesity uncovered

Doctors may soon be able to use AI for cancer detection

Innovation in neuroscience drug discovery - eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging