Neurology News and Research

Latest Neurology News and Research

AAPS honors Morphotek with 2012 Excellence in Ligand Binding Assays Award

Morphotek, Inc., a subsidiary of Eisai Inc., announced today that The American Association of Pharmaceutical Scientists (AAPS) has awarded its 2012 Excellence in Ligand Binding Assays Award to the Bioanalytical Development group from Morphotek for their abstract, "Development and Validation of a Pharmacokinetic Assay on the Gyrolab Platform for Use in Phase II/III Clinical Studies."

31 May 2012

MD Bioproducts launches new subtype specific antibody as marker for AS

MD Bioproducts launches a new subtype specific antibody as a marker for ankylosing spondylitis (AS): HLA-B*2705. The anti-HLA-B*2705 antibody, clone MARB4, has been validated for use in flow cytometry, tissue staining and immunoprecipitation.

30 May 2012

Exendin-4 significantly minimizes damage in TBI animal models

Although the death toll is relatively low for people who suffer from traumatic brain injury (TBI), it can have severe, life-long consequences for brain function. TBI can impair a patient's mental abilities, impact memory and behavior, and lead to dramatic personality changes. And long-term medical treatment carries a high economic cost.

30 May 2012

Better education early in life may help protect cognitive abilities

Exposure to solvents at work may be associated with reduced thinking skills later in life for those who have less than a high school education, according to a study published in the May 29, 2012, print issue of Neurology, the medical journal of the American Academy of Neurology.

29 May 2012

EMA CHMP issues positive opinion to Eisai’s Fycompa for treatment of partial-onset seizures

Eisai announced today that the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion for the use of Fycompa (perampanel) as an adjunctive treatment of partial-onset seizures, with or without secondarily generalised seizures, in patients with epilepsy aged 12 years and older.

29 May 2012

Tβ4 offers both neurorestoration and neuroprotection after TBI

RegeneRx Biopharmaceuticals, Inc. reported that data showing that Thymosin beta 4 (Tβ4) "provides both neuroprotection and neurorestoration after traumatic brain injury (TBI)," was published in the current (May 2012) edition of the Journal of Neurosurgery, 116:1081-1092.

28 May 2012

UCLA Face Transplantation Program seeks candidates for clinical trial

The UCLA Health System has launched the UCLA Face Transplantation Program, the first surgical program of its kind in the western United States and one of only a handful in the nation.

25 May 2012

UCSF receives $20M Sandler Foundation gift for neuroscience research and care

UCSF has received a challenge gift of $20 million from the Sandler Foundation that will provide major support for the university's groundbreaking research and clinical care efforts regarding neurological diseases.

25 May 2012

FDA advisory committee votes in favor of Pfizer's tafamidis meglumine

Pfizer Inc. announced today that the United States Food and Drug Administration's (FDA) Peripheral and Central Nervous System Drugs Advisory Committee voted on Pfizer's clinical data package for tafamidis meglumine.

25 May 2012

Study sheds light on role of microglia in the normal brain

Researchers have shown in mice how immune cells in the brain target and remove unused connections between brain cells during normal development. This research, supported by the National Institutes of Health, sheds light on how brain activity influences brain development, and highlights the newly found importance of the immune system in how the brain is wired, as well as how the brain forms new connections throughout life in response to change.

24 May 2012

Brain cells prune circuits in the brain by eating away excess synapses

We’re born with our brains prewired, but as information comes in from our environment, this circuitry is updated. A study from Boston Children’s Hospital provides a new glimpse of how this happens: Brain cells known as microglia, tuned into the crosstalk between neurons, literally engulf unnecessary connections, known as synapses, and prune them away.

24 May 2012

NYULMC opens new 327,000 square-foot Ambulatory Care Center

As part of its plan to expand access to a wide array of outpatient services, NYU Langone Medical Center has opened a new 327,000 square-foot Ambulatory Care Center (ACC) at 240 East 38th Street.

24 May 2012

Omega-3 fatty acids may provide more benefits for elderly people with Alzheimer's

According to a recent study published online in Neurology, Omega-3 fatty acids, like those found in Omega XL fish oil extract containing DHA and EPA from the New Zealand green-lipped mussel, may provide more benefits for elderly people suffering from Alzheimer's.

24 May 2012

Children with obesity more likely to have idiopathic intracranial hypertension

Children who are overweight or obese -- particularly older, non-Hispanic white girls -- are more likely to have a neurological disorder known as idiopathic intracranial hypertension, a rare condition that can result in blindness, according to a new Kaiser Permanente study published in The Journal of Pediatrics.

24 May 2012

Bayer submits regorafenib NDA with FDA for treatment of mCRC

Bayer HealthCare announced today that it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking approval for the oral multi-kinase inhibitor regorafenib for the treatment of patients with metastatic colorectal cancer.

24 May 2012

Alteplase can benefit stroke patients aged over 80 years according to new studies

The Lancet today publishes two papers Online First about the use of alteplase in stroke, timed to coincide with their presentation at the European Stroke Conference in Lisbon, Portugal.

23 May 2012

Botch protein appears to play an important regulatory role in forming neurons, other cell types

Johns Hopkins scientists have discovered a protein that appears to play an important regulatory role in deciding whether stem cells differentiate into the cells that make up the brain, as well as countless other tissues.

23 May 2012

Statins may reduce hospital stay for patients with stroke

A new study suggests that using cholesterol-lowering medications known as statins after having a stroke may increase the likelihood of returning home and lessen the chance of dying in the hospital.

22 May 2012

Bayer’s Nexavar Phase 3 trial on NSCLC does not meet primary endpoint

Bayer HealthCare Pharmaceuticals and Onyx Pharmaceuticals, Inc. today announced that a Phase 3 trial evaluating Nexavar (sorafenib) tablets in patients with advanced relapsed or refractory non-squamous non-small cell lung cancer (NSCLC) whose disease progressed after two or three previous treatments, did not meet its primary endpoint of improving overall survival.

22 May 2012

$Children with pelvic and thigh fractures rarely develop dangerous blood clots$

Children with pelvic and thigh fractures rarely develop dangerous blood clots

Children with pelvic and thigh fractures develop dangerous blood clots so rarely that anti-clotting therapy should be given only to those with underlying conditions that increase clotting risk, according to a study from Johns Hopkins Children's Center.

21 May 2012