Pain News and Research

Latest Pain News and Research

Positive data from Nektar’s NKTR-192 Phase 1a study on acute pain

Nektar Therapeutics announced today that positive data from the first single-ascending dose Phase 1a clinical study of NKTR-192, the company's novel short-acting mu-opioid analgesic candidate, demonstrate that the drug candidate achieved its target pharmacokinetic profile.

19 Sep 2012

‘Disappointing’ findings for spinal manipulative therapy

Spinal manipulative therapy for acute low-back pain appears to be no better than other existing therapies for reducing pain and improving functional status, show the findings of a Cochrane review.

18 Sep 2012

Orthopedists should suspect necrotizing fasciitis in patients with out of proportion pain

Dr. Russell Russo, an Orthopedic Surgeon at LSU Health Sciences Center New Orleans, and other researchers stress that orthopedists should have a high index of suspicion for necrotizing fasciitis, or flesh-eating bacterial infection, in every patient with pain or other symptoms that are out of proportion to the initial diagnosis. Their recommendations are published in the September 2012 issue of Orthopedics Today.

17 Sep 2012

Limited positive effect of Tafamidis in neurological disorders

Tafamidis meglumine was approved in November 2011 for the treatment of transthyretin amyloidosis in adults.

17 Sep 2012

Researchers investigate African plants effective in treating snakebite

A PhD student at the University of Copenhagen has drawn on nature's own pharmacy to help improve the treatment of snakebites in Africa.

17 Sep 2012

MIT engineers use ultrasound waves to enhance permeability of skin to drugs

Using ultrasound waves, MIT engineers have found a way to enhance the permeability of skin to drugs, making transdermal drug delivery more efficient. This technology could pave the way for noninvasive drug delivery or needle-free vaccinations, according to the researchers.

15 Sep 2012

Roundup: Calif. to probe hospital/doctor consolidations; Cuccinelli warns Va. health board on abortion clinic rules

California's attorney general has launched a broad investigation into whether growing consolidation among hospitals and doctor groups is pushing up the price of medical care, reflecting increasing scrutiny by antitrust regulators of medical-provider deals.

15 Sep 2012

FDA approves Lannett’s ANDA for Butalbital, Acetaminophen and Caffeine Tablets

Lannett Company, Inc. today announced that it has received approval from the U.S. Food and Drug Administration (FDA) of its Abbreviated New Drug Application (ANDA) for Butalbital, Acetaminophen and Caffeine Tablets, USP, 50mg/325mg/40mg.

15 Sep 2012

Severe egg allergy treatment shows promise

Specific oral tolerance induction with raw hen’s egg can reduce the severity of egg allergy in affected children, show study findings.

14 Sep 2012

Objective response rate promising after crizotinib for NSCLC

More than half of the latest evaluated participants from the ongoing phase II PROFILE 1005 trial of crizotinib against ALK-positive advanced non-small-cell lung cancer, achieved an objective tumor response, report researchers.

14 Sep 2012

Emmaus Medical to complete target enrollment in L-Glutamine Phase III trial for sickle cell disease

In conjunction with Sickle Cell Awareness Month, Emmaus Medical, Inc., a specialty pharmaceutical and regenerative medicine technology company, announced that its U.S. Phase III clinical trial to study L-Glutamine as a treatment for sickle cell disease is nearing target enrollment completion, with investigation now underway at more than 30 clinical study sites throughout the U.S.

14 Sep 2012

Autologous skin grafts heal chronic foot ulcers

Scientists have successfully treated chronic diabetic foot ulcers using skin grafts grown from individual patient cell samples.

13 Sep 2012

Think ‘glass half full’ to reduce pain after breast surgery

Women who undergo surgery for breast cancer are less likely to experience postoperative pain if they have an optimistic personality, but are more likely to experience it if they already had preoperative pain, shows an analysis of the Study of Recovery after Breast Surgery.

13 Sep 2012

University of Maryland study findings advance navel nephrectomy as standard of care

In the largest study of its kind, living donors who had a kidney removed through a single port in the navel report higher satisfaction in several key categories, compared to donors who underwent traditional multiple-port laparoscopic removal.

13 Sep 2012

Federal judges end challenge to Idaho's 'fetal pain' law that bans some abortion

The appeals panel says the woman bringing the suit didn't have standing to stop the law since she wasn't charged with a crime. In the meantime, however, the judges also found that the law places an "undue burden" on women seeking abortions.

13 Sep 2012

Loss of normal microbial diversity may be culprit behind chronic sinusitis

A common bacteria ever-present on the human skin and previously considered harmless, may, in fact, be the culprit behind chronic sinusitis, a painful, recurring swelling of the sinuses that strikes more than one in ten Americans each year, according to a study by scientists at the University of California, San Francisco.

13 Sep 2012

Glenmark's GBR 500 enters Phase II clinical development for severe ulcerative colitis

Glenmark Pharmaceuticals S.A. (GPSA), a wholly-owned subsidiary of Glenmark Pharmaceuticals Limited (GPL), announced today that GBR 500 has entered Phase II clinical development.

13 Sep 2012

Ibuprofen or acetaminophen may increase risk of hearing loss among women

Headache? Back pain? At the first sign of pain, you might reach for a pain-relieving medicine to sooth your bodily woes. Analgesics are the most frequently used medications in the United States and are commonly used to treat a variety of medical conditions. But although popping a pill may make the pain go away, it may do some damage to your ears.

13 Sep 2012

Blood pressure, oxygen saturation predict death in terminally ill

The most reliable events that predict impending death in terminally ill cancer patients being treated palliatively are decreased blood pressure and low oxygen saturation, show study results.

12 Sep 2012