Pain News and Research

Latest Pain News and Research

Trevena commences TRV130 Phase I clinical trial for severe post-operative pain

Trevena, Inc., the leader in discovery and development of G-protein coupled receptor (GPCR) biased ligands, announced today the initiation of a Phase I clinical trial of TRV130, a novel candidate designed for the intravenous treatment of moderate-to-severe post-operative pain.

13 Feb 2012

Medasys Prometra programmable implantable drug pump receives FDA PMA approval

Medasys Inc., a medical device company focused on providing implantable drug delivery solutions, announced today that it has received PMA approval from the U. S. Food and Drug Administration for its Prometra programmable implantable drug pump.

13 Feb 2012

Clinical observation should not be replaced with MRI for treating people with hip pain

When it comes to treating people with hip pain, physicians should not replace clinical observation with the use of magnetic resonance images (MRI), according to research being presented today at the American Orthopaedic Society for Sports Medicine's (AOSSM) Specialty Day in San Francisco, CA.

13 Feb 2012

Regeneron reports total revenues of $123.0M for fourth quarter 2011

Regeneron Pharmaceuticals, Inc. announced financial and operating results for the fourth quarter and full year 2011 and provided an update on development programs.

13 Feb 2012

ICN Food List for interstitial cystitis/bladder pain syndrome patients

When one cup of coffee, tea or cranberry juice can trigger days of pain and/or bladder discomfort, interstitial cystitis, overactive bladder and other urology patients often develop an unhealthy fear of food. A new iPhone and iPad application, (ICN Food List) seeks to change that by giving patients an easy to use food list and database that they can use while shopping and eating out at restaurants.

13 Feb 2012

Incident malignancy four times higher among children with JIA

New research reports that incident malignancy among children with juvenile idiopathic arthritis (JIA) is four times higher than in those without the disease. Findings now available in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR), suggest JIA treatment, such as tumor necrosis factor (TNF) inhibitors, does not necessarily explain the development of cancer in this pediatric population.

13 Feb 2012

State legislatures face tough decisions on long-term care, abortion rules, pain prescriptions, coordinated care

Cost-saving measures proposed by Gov. Scott Walker's administration to Family Care programs for frail elderly and people with disabilities are coming under fire ... County Executive Chris Abele said the county didn't have the staff to do "intensive prevention efforts" envisioned by the state reform ideas. ... The state's proposed sustainability modifications to the program include an emphasis on shifting clients from publicly financed help to "natural supports" - meaning a greater reliance on family members for care.

13 Feb 2012

Preliminary results from Soligenix SGX201 Phase 1/2 trial on acute radiation enteritis

Soligenix, Inc., a development stage biopharmaceutical company, announced preliminary results today from a Phase 1/2 clinical trial evaluating SGX201, a time-release formulation of oral beclomethasone 17,21-dipropionate (oral BDP), for the prevention of acute radiation enteritis.

10 Feb 2012

Bupivacaine may effectively manage pain after total knee replacement

Researchers at the Rothman Institute at Jefferson have shown that local anesthesia delivered through a catheter in the joint, intraarticularly, may be more beneficial than traditional opioids such as morphine and Oxycontin for pain management following total knee replacement surgery.

10 Feb 2012

Shorter stay protocols for TKR patients may increase risk of mortality, readmission

No previous research has quantified and compared the costs and outcomes between total knee replacement (TKR) patients who have differing lengths of hospital stay following surgery.

10 Feb 2012

Study: Syncope results in unexplained cardiac arrests

Up to 45,000 sudden cardiac arrests occur each year in Canada, and less than five percent survive. In some of these cases, the event cannot be explained by the presence of underlying heart disease. In order to identify people at risk of these unexplained cardiac events, a newly published study examined the presence of certain warning symptoms that are present in people who have been resuscitated from a cardiac arrest.

10 Feb 2012

Children with multiple psychosomatic symptoms more likely to experience physical abuse

Children who display multiple psychosomatic symptoms, such as regular aches and pains and sleep and appetite problems, are more than twice as likely to be experiencing physical abuse at home than children who do not display symptoms, according to a study in the March edition of Acta Paediatrica.

10 Feb 2012

Cancer-related fatigue linked to muscle mass and strength

Many patients with advanced cancer suffer from cachexia, a condition also called body-wasting or wasting syndrome, which causes significant weight loss, extreme fatigue and reduces quality of life.

10 Feb 2012

Single fibronectin injection can prevent chronic pain development after SCI

Chronic neuropathic pain following a spinal cord injury is common and very difficult to treat, but a new therapeutic strategy requiring a one-time injection into the spinal column has potential to improve patient outcomes.

9 Feb 2012

Women less satisfied with pain control after TKR surgery

Increased pain following surgery has long been linked to anxiety and "catastrophizing," an extreme response to stress. In a new study presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), 97 patients - men and women - who were about to undergo minimally invasive total knee replacement (TKR) surgery, completed a brief survey to quantify their level of anxiety, as well as their typical level of anxiety and potential for catastrophizing. Pain data was then collected for seven days following surgery.

9 Feb 2012

Antidepressants make patients feel less satisfied after THR

Patients taking antidepressants up to three years prior to undergoing a total hip replacement (THR) were more likely to report greater pain before and after surgery and less satisfaction with their procedure, according to new research presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).

9 Feb 2012

Valley Pain Consultants announces new office location

Valley Pain Consultants, a division of Valley Anesthesiology Consultants, announced the relocation of its Paradise Valley office to 3301 N. Miller Road, Suite 120, Scloottsdale, AZ 85251.

9 Feb 2012

Exercise can reduce pain, improve physical function in individuals with OA

The benefits of exercise in minimizing pain and improving mobility for individuals living with osteoarthritis has been well documented.

8 Feb 2012

Genzyme announces four-year data from eliglustat tartrate phase 2 trial on Gaucher disease type 1

Genzyme, a Sanofi company, announced today four-year follow-up data from patients enrolled in the phase 2 clinical trial for its investigational oral therapy for Gaucher disease type 1 known as eliglustat tartrate.

8 Feb 2012

New combination laser therapy effective in treating melasma

On the surface, it would seem as though the skin condition melasma (commonly referred to as the "mask of pregnancy") and tattoos would have little in common. However, they both affect a person's skin, can be quite difficult to treat or remove and, now, dermatologists are discovering new laser therapies which enhance treatment for both conditions.

8 Feb 2012