Parkinson's Disease News and Research

Latest Parkinson's Disease News and Research

Molecules self-assemble to provide new therapeutic treatments

Researchers in the laboratory of Samuel I. Stupp at Northwestern University have an interesting approach for tackling some major health problems: gather raw materials and then let them self-assemble into structures that can address a multitude of medical needs.

16 Feb 2009

Safinamide significantly improved motor function in patients with advanced Parkinson's disease

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, and its partner Newron Pharmaceuticals SpA has announced that the first Phase III trial of investigational agent safinamide as adjunctive therapy to levodopa (study 016) met its primary endpoint by increasing daily "ON" time in mid- to late-stage Parkinson's disease patients with motor fluctuations by 1.3 hours.

5 Feb 2009

Link found between genetic and environmental causes of Parkinson's disease

Scientists at the Whitehead Institute for Biomedical Research have found that a single gene, known as PARK9, protects cells from manganese toxicity and rescues neurons from over-expression of the protein alpha-synuclein.

3 Feb 2009

Genetic change prevents cell death in mouse model of Parkinson's disease

By shifting a normal protective mechanism into overdrive, a University of Wisconsin-Madison scientist has completely shielded mice from a toxic chemical that would otherwise cause Parkinson's disease.

2 Feb 2009

Link found between Parkinson's disease genes and manganese poisoning

A connection between genetic and environmental causes of Parkinson's disease has been discovered by a research team led by Aaron D. Gitler, PhD, Assistant Professor in the Department of Cell and Developmental Biology at the University of Pennsylvania School of Medicine.

2 Feb 2009

Sport related concussions affect mental and physical processes later in life

Researchers have found the first evidence that athletes who were concussed during their earlier sporting life show a decline in their mental and physical processes more than 30 years later.

29 Jan 2009

Early treatment with rasagiline (Azilect) for Parkinson's best

There is hope that the drug rasagiline can do what no other medication for Parkinson's disease now does -- slow the progression of a devastating degenerative brain disease that eventually robs people of their ability to move and function.

27 Jan 2009

Genetic testing may not lead to demand for 'designer babies'

A new study by researchers at NYU Langone Medical Center found a high desire for additional genetic testing among consumers for life altering and threatening medical conditions including mental retardation, blindness, deafness, cancer, heart disease, dwarfism and shortened lifespan from death by 5 years of age.

27 Jan 2009

Leaky membranes: Another sign of old age

As parts of us age, even the membrane bound nuclei , which house the genetic instructions for life that are "written" in our DNA, begin to show considerable wear and tear, suggests a new report in the January 23rd issue of the journal Cell, a Cell Press publication.

23 Jan 2009

Dynamical theory and novel 4-D colorimetric method reveal modus operandi of intact living brain

For the brain to achieve its intricate functions such as perception, action, attention and decision making, neural regions have to work together yet still retain their specialized roles.

21 Jan 2009

Researchers identify biochemical switch required for nerve cells to respond to DNA damage

The finding, scheduled for advance online publication in Nature Cell Biology, illuminates a connection between proteins involved in neurodegenerative disease and in cells' response to DNA damage.

19 Jan 2009

Electrical stimulation of the brain offers hope for Parkinson's sufferers

Electrical stimulation of the brain -- a treatment in which a pacemaker-like device sends pulses to electrodes implanted in the brain -- is riskier than drug therapy but may hold significant benefits for those with Parkinson's disease who no longer respond well to medication alone.

14 Jan 2009

Discovery of mechanism that may explain Parkinson's and other neurological disorders

Studying just eight families worldwide, the international team of researchers have discovered a genetic defect that results in profound depression and parkinsonism in a disorder known as Perry syndrome.

12 Jan 2009

New cataract early detection device

A compact fiber-optic probe developed for the space program has now proven valuable for patients in the clinic as the first non-invasive early detection device for cataracts, the leading cause of vision loss worldwide.

8 Jan 2009

Lasers show potential to 'zap' amyloid proteins

Researchers have found that a technique used to visualize amyloid fibers in the laboratory might have the potential to destroy them in the clinic.

7 Jan 2009

Clioquinol - gastrointestinal drug could become anti-aging treatment

Recent animal studies have shown that clioquinol – an 80-year old drug once used to treat diarrhea and other gastrointestinal disorders – can reverse the progression of Alzheimer's, Parkinson's and Huntington's diseases.

6 Jan 2009

Deep brain stimulation helps advanced Parkinson's disease patients

Patients with advanced Parkinson disease (PD) who received deep brain stimulation treatment had more improvement in movement skills and quality of life after six months than patients who received other medical therapy, but also had a higher risk of a serious adverse events, according to a study in the January 7 issue of JAMA.

6 Jan 2009

Apolipoprotein D protects against Alzheimer's

Do Carmo and her collaborators have successfully demonstrated the protective and reparative role of apolipoprotein D, or ApoD, in neurodegenerative diseases. Their discovery suggests interesting avenues for preventing and slowing the progression of this type of illness.

6 Jan 2009

Stem cells from human testes can change into other body tissues

Scientists at the Stanford University School of Medicine and at UC-San Francisco have succeeded in isolating stem cells from human testes.

5 Jan 2009

Parkinson's increases risk for orthopaedic conditions

Although Parkinson's disease (PD) is a neurological disorder, according to an article in the January 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons, the disease also increases a person's risk of experiencing complicated orthopaedic conditions.

5 Jan 2009