Pharmacology News and Research

Latest Pharmacology News and Research

Mitosis study identifies new potential target for cancer therapy

Structural biologists show in a new study that an apparently key step in the process of cell division depends on a unique interaction among specific proteins, including one that is strongly linked to cancer. Their hope now is that the detailed new characterization of the interaction will make it a target for exploring a new cancer therapy.

31 Aug 2016

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

A study in The Journal of Cell Biology by scientists at the University of Massachusetts Medical School reveals important new details about the inner workings of the CRISPR-Cas9 machinery in live cells that may have implications for the development of therapeutics that use the powerful gene editing tool.

30 Aug 2016

Novel compound provides safe, effective pain relief with zero abuse potential in animal model

Since the isolation of morphine from opium in the 19th century, scientists have hoped to find a potent opioid analgesic that isn't addictive and doesn't cause respiratory arrest with increased doses.

30 Aug 2016

Gentle combination of FDA-approved drugs could combat photoreceptor degeneration in mice

In microseconds, every light ray that enters the eye triggers an explosion of coordinated cellular events.

29 Aug 2016

Engineered gut bacteria may one day help reduce negative health effects of obesity

A new therapy that involves engineered gut bacteria may one day help reduce the health problems that come with obesity. Incorporating the engineered bacteria into the guts of mice both kept them from gaining weight and protected them against some of the negative health effects of obesity.

28 Aug 2016

MRI-guided focused ultrasound treatment improves quality of life in patients with essential tremor

Treatment with MRI-guided focused ultrasound significantly improves tremors and quality of life in patients with essential tremor (ET), the most common movement disorder, according to a study published in the August 25 issue of the New England Journal of Medicine.

27 Aug 2016

Anesthetic administered with nasal spray effective in preventing pain during dental treatment

A fear of pain causes many people with dental phobias to avoid or delay needed treatment. In some cases, the injection of a numbing agent can be the most painful part of the visit.

26 Aug 2016

IRB Barcelona review article provides insights into emerging field of shuttle peptides

IRB Barcelona researchers publish a review article on the emerging field of drug transporters that have the capacity to reach the brain more efficiently.

26 Aug 2016

Novel inhibitory brain receptor reduces seizure-like activity in pubertal mice

More than half of children with epilepsy outgrow their seizures, yet the mechanism underlying this remission is unknown.

26 Aug 2016

UNC researchers map anxiety circuit in the brain that may explain side effects of antidepressants

More than 100 million people worldwide take selective serotonin reuptake inhibitors (SSRIs), such as Prozac and Zoloft, to treat depression, anxiety and related conditions, but these drugs have a common and mysterious side effect: they can worsen anxiety in the first few weeks of use, which leads many patients to stop treatment.

25 Aug 2016

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

An atomic level analysis has revealed how two classes of calcium channel blockers, widely prescribed for heart disease patients, produce separate therapeutic effects through their actions at different sites on the calcium channel molecule.

25 Aug 2016

New noninvasive treatment option improves quality of life in patients with essential tremor

25 Aug 2016

TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

The part of the jawbone containing tooth sockets is known as alveolar bone, and its loss over time or following dental disease may ultimately result in tooth loss.

23 Aug 2016

Researcher aims to shed new light on inner workings of the retina

One of the more studied parts of the human anatomy, the retina -- the neural layer at the back of the eye that senses light -- still has secrets to reveal.

23 Aug 2016

Research offers new insights into sleep/awake patterns in animals

Research from University of California, Irvine scientists and their colleagues offers new insights into why many animals sleep at night and are active during the day, while others do the reverse.

23 Aug 2016

New study examines effectiveness of pictogram labels on medication-related road traffic crash risk

A new study questions the effectiveness of using pictogram message on the labels of anxiety and sleep medications that interfere with driving - an approach this is currently implemented across France.

22 Aug 2016

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Using technology they developed, UT Southwestern Medical Center researchers have identified a previously unknown role of a certain class of proteins: as regulators of gene activity and RNA processing.

16 Aug 2016

Scientists identify potential mechanism that paves way for improved treatment of fungal infections

By identifying new compounds that selectively block mitochondrial respiration in pathogenic fungi, Whitehead Institute scientists have identified a potential antifungal mechanism that could enable combination therapy with fluconazole, one of today's most commonly prescribed fungal infection treatments.

11 Aug 2016

Scientists clarify how tumour cells kill specific cells in vascular wall to establish metastases

Many cancers only become a mortal danger if they form metastases elsewhere in the body. Such secondary tumours are formed when individual cells break away from the main tumour and travel through the bloodstream to distant areas of the body.

11 Aug 2016

Study finds reduced activity of ACMSD enzyme in people with suicidal behavior

It is known that people who have attempted suicide have ongoing inflammation in their blood and spinal fluid. Now, a collaborative study from research teams in the U.S., Sweden and Australia published in Translational Psychiatry shows that suicidal patients have a reduced activity of an enzyme that regulates inflammation and its byproducts.

10 Aug 2016

Pharmacology News and Research

Latest Pharmacology News and Research

Mitosis study identifies new potential target for cancer therapy

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

Novel compound provides safe, effective pain relief with zero abuse potential in animal model

Gentle combination of FDA-approved drugs could combat photoreceptor degeneration in mice

Engineered gut bacteria may one day help reduce negative health effects of obesity

MRI-guided focused ultrasound treatment improves quality of life in patients with essential tremor

Anesthetic administered with nasal spray effective in preventing pain during dental treatment

IRB Barcelona review article provides insights into emerging field of shuttle peptides

Novel inhibitory brain receptor reduces seizure-like activity in pubertal mice

UNC researchers map anxiety circuit in the brain that may explain side effects of antidepressants

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

New noninvasive treatment option improves quality of life in patients with essential tremor

TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

Researcher aims to shed new light on inner workings of the retina

Research offers new insights into sleep/awake patterns in animals

New study examines effectiveness of pictogram labels on medication-related road traffic crash risk

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Scientists identify potential mechanism that paves way for improved treatment of fungal infections

Scientists clarify how tumour cells kill specific cells in vascular wall to establish metastases

Study finds reduced activity of ACMSD enzyme in people with suicidal behavior

Industry Focus eBook - Pharmaceutical manufacturing (2nd edition) eBook

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Pharmacology News and Research

Latest Pharmacology News and Research

Industry Focus eBook - Pharmaceutical manufacturing (2nd edition) eBook

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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