Pharmacology News and Research

Latest Pharmacology News and Research

Radiotherapy plus panobinostat more effective for aggressive, recurrent brain cancer

Radiotherapy effectively damages brain tumors but the cancer cells can repair themselves in order to live on. Now, researchers at Sidney Kimmel Cancer Center have tested a strategy that combines radiotherapy with a drug that shuts down the ability of tumor to mend themselves.

27 Feb 2016

Scientists reveal how the brain processes information with lightning speed

Surprisingly complex interactions between neurotransmitter receptors and other key proteins help explain the brain's ability to process information with lightning speed, according to a new study.

27 Feb 2016

Protein p62 acts as molecular brake to keep inflammation in check, avoid collateral damage

Inflammation is a Catch-22: the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and sometimes leading to organ failure and death. Researchers at University of California, San Diego School of Medicine have discovered that a protein known as p62 acts as a molecular brake to keep inflammation in check and avoid collateral damage.

26 Feb 2016

Scientists develop new optical technique to observe neurotransmitter activity of individual synapses

Columbia University scientists have developed a new optical technique to study how information is transmitted in the brains of mice. Using this method, they found that only a small portion of synapses -- the connections between cells that control brain activity--may be active at any given time.

26 Feb 2016

Omega-3 fatty acids can lower risk of breast cancer in postmenopausal obese women

Omega-3 fatty acids may lower the risk of breast cancer in postmenopausal obese women, according to researchers.

24 Feb 2016

Gamma Knife and RapidArc equally effective at eradicating cancer in the brain

While two advanced radiosurgery approaches — Gamma Knife and RapidArc — offer different strengths, they are equally effective at eradicating cancer in the brain, say researchers at Sidney Kimmel Cancer Center.

24 Feb 2016

New TAU study suggests potential therapeutic pathway to keep osteosarcoma lesions dormant

Osteosarcoma is a cancer that develops in the bones of children and adolescents. It is one of the most aggressive cancers, with only a 15 per cent, five-year survival rate when diagnosed in an advanced metastatic stage. There are approximately 800 new cases diagnosed each year in the US, and no viable treatments.

23 Feb 2016

Researchers Pinpoint Potential Enzyme For T-Cell Leukemia Treatment

For the first time, researchers at Boston University have shown that T-cell leukemia cells use a particular cycle, called the TCA or Kreb cycle, to support their growth and survival.

23 Feb 2016

Two Johns Hopkins scientists named among 105 winners of Presidential Early Career Awards

Namandje Bumpus, Ph.D., and Jordan Green, Ph.D., of the Johns Hopkins University School of Medicine are among 105 winners of Presidential Early Career Awards for Scientists and Engineers, which were announced by the White House on Feb. 18.

23 Feb 2016

Penn researchers develop new mathematical model to estimate mutation rates in the human genome

It turns out that the type, how frequent, and where new mutations occur in the human genome depends on which DNA building blocks are nearby, found researchers from the Perelman School of Medicine at the University of Pennsylvania in an advanced online study published this week in Nature Genetics.

22 Feb 2016

New discoveries provide further evidence for benefits of a good night's sleep

Why does sleeping on it help? This is the question tackled by new research at the University of Bristol, which reveals how brain activity during sleep sorts through the huge number of experiences we encounter every day, filing only the important information in memory.

22 Feb 2016

NK cells produce VEGF-A that promotes tumor growth

The immune system protects the body against cancer cells. The Elimination of cancer cells is an important task of NK cells. For NK cells to function properly, they require the activator STAT5.

19 Feb 2016

AMRI's net revenues increase $126.4M to 46% in fourth quarter 2015

AMRI today reported financial and operating results for the fourth quarter and full year ended December 31, 2015 and provided an outlook for 2016.

17 Feb 2016

New optogenetic technology could turn on immune cells to attack melanoma tumors

A new optogenetic technology developed at UMass Medical School, called optogenetic immunomodulation, is capable of turning on immune cells to attack melanoma tumors in mice. Using near-infrared light, UMMS researchers have shown they can selectively activate an immune response by controlling the flow of calcium ions into the cell. This breakthrough could lead to less invasive, and more controlled and selective, immunotherapies for cancer treatment.

17 Feb 2016

Synthetic RNA and DNA could reverse protein deficiency that causes Friedreich's ataxia

Researchers at UT Southwestern Medical Center have identified synthetic RNA and DNA that reverses the protein deficiency causing Friedreich's ataxia, a neurological disease for which there is currently no cure.

17 Feb 2016

Digoxin drug can help protect against atherosclerosis

New research in mice provides convincing evidence that digoxin, a drug prescribed to treat atrial fibrillation, can help protect against atherosclerosis.

17 Feb 2016

Aerobic exercise may prevent alcohol-related liver damage

According to the Centers for Disease Control and Prevention, excessive alcohol use is responsible for more than 80,000 deaths in the United States each year. Over time, excessive drinking can lead to several chronic conditions, such as fatty liver disease and cirrhosis.

16 Feb 2016

Drugs designed to curb Rac1 signaling pathway may help relieve inflammatory pain in sufferers

New research uncovers a cascade of reactions within nerve cells that relay sensations of pain associated with inflammation. The findings, which are published in the British Journal of Pharmacology, indicate that drugs designed to curb this pathway may help relieve inflammatory pain in sufferers.

11 Feb 2016

Some heart disease drugs, antibiotics show promising perspectives in treating cancers

North American researchers have identified drugs that showed promising perspectives in treating cancers, according to a recent study published in Cancer Research.

9 Feb 2016

UC San Diego School of Medicine launches new NAFLD Research Center

Roughly one-quarter of all Americans - an estimated 100 million adults and children - have nonalcoholic fatty liver disease (NAFLD), a chronic condition that can lead to cirrhosis, liver cancer and liver failure.

9 Feb 2016

Pharmacology News and Research

Latest Pharmacology News and Research

Radiotherapy plus panobinostat more effective for aggressive, recurrent brain cancer

Scientists reveal how the brain processes information with lightning speed

Protein p62 acts as molecular brake to keep inflammation in check, avoid collateral damage

Scientists develop new optical technique to observe neurotransmitter activity of individual synapses

Omega-3 fatty acids can lower risk of breast cancer in postmenopausal obese women

Gamma Knife and RapidArc equally effective at eradicating cancer in the brain

New TAU study suggests potential therapeutic pathway to keep osteosarcoma lesions dormant

Researchers Pinpoint Potential Enzyme For T-Cell Leukemia Treatment

Two Johns Hopkins scientists named among 105 winners of Presidential Early Career Awards

Penn researchers develop new mathematical model to estimate mutation rates in the human genome

New discoveries provide further evidence for benefits of a good night's sleep

NK cells produce VEGF-A that promotes tumor growth

AMRI's net revenues increase $126.4M to 46% in fourth quarter 2015

New optogenetic technology could turn on immune cells to attack melanoma tumors

Synthetic RNA and DNA could reverse protein deficiency that causes Friedreich's ataxia

Digoxin drug can help protect against atherosclerosis

Aerobic exercise may prevent alcohol-related liver damage

Drugs designed to curb Rac1 signaling pathway may help relieve inflammatory pain in sufferers

Some heart disease drugs, antibiotics show promising perspectives in treating cancers

UC San Diego School of Medicine launches new NAFLD Research Center

Industry Focus - Biopharma eBook

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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Pharmacology News and Research

Latest Pharmacology News and Research

Industry Focus - Biopharma eBook

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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