Pharmacology News and Research

Latest Pharmacology News and Research

Medical marijuana offers hope for kids with uncontrolled seizures

Desperate for relief, parents are taking unusual steps to help children plagued with seizures. The relief, however, comes in a most unlikely form: marijuana.

9 Feb 2016

Implantable device could help deliver toxic cocktail of drugs directly to pancreatic tumors

A highly lethal cancer sometimes requires large doses of highly toxic drugs. However, a blitzkrieg approach can be unfeasible for some patients due to severe side effects. Now a powerhouse team of researchers at the University of North Carolina at Chapel Hill has revealed that an implantable device can deliver a particularly toxic cocktail of drugs directly to pancreatic tumors to stunt their growth or in some cases, shrink them - all while showing signs that the rest of the body would be spared toxic side effects.

9 Feb 2016

Drinking extra 2 cups of coffee per day may reduce cirrhosis risk by 44%

Regular consumption of coffee was linked with a reduced risk of liver cirrhosis in a review of relevant studies published before July 2015.

1 Feb 2016

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

RNA is becoming an interesting drug target as it takes possible intervention back one step to the synthesis of a target protein, instead of trying to block or inhibit a process.

1 Feb 2016

HUYA, Eisai sign exclusive license agreement for HBI-8000 in Japan and other Asian countries

HUYA Bioscience International President, CEO, Executive Chairman & Founder Dr. Mireille Gillings announced that Eisai Co., Ltd. has acquired from HUYA an exclusive license agreement for HBI-8000 in Japan, South Korea, Thailand, Malaysia, Indonesia, Philippines, Vietnam and Singapore.

1 Feb 2016

Framework for improving chemical hazard assessment without animals

A new paper published in Regulatory Toxicology and Pharmacology, co-authored by the Physicians Committee for Responsible Medicine, calls for ongoing development and regulatory acceptance of adverse outcome pathways (AOPs), a framework for improving chemical hazard assessment by prioritizing modern test methods that reduce animal use.

31 Jan 2016

HIV protein alters activity of networked neurons

Nearly half of HIV infected patients suffer from impaired neurocognitive function. The HIV protein transactivator of transcription (Tat) is an important contributor to HIV neuropathogenesis because it is a potent neurotoxin that continues to be produced despite treatment with antiretroviral therapy.

31 Jan 2016

FDA-approved blood pressure drug reduces cell damage linked to Alzheimer's disease

In laboratory neuronal cultures, an FDA-approved drug used to treat high blood pressure reduced cell damage often linked to Alzheimer's disease, say researchers at Georgetown University Medical Center and the National Institutes of Health.

30 Jan 2016

Researchers develop new painkiller as strong as morphine but not addictive

Researchers at Tulane University and Southeast Louisiana Veterans Health Care System have developed a painkiller that is as strong as morphine but isn't likely to be addictive and with fewer side effects, according to a new study in the journal Neuropharmacology.

29 Jan 2016

Researchers discover potential candidates for development of novel targeted therapies for blood cancers

A research team from the Department of Pharmacology and Therapeutics at Roswell Park Cancer Institute has discovered a new class of small-molecule compounds that are good candidates for development of novel targeted therapies in the treatment of leukemia and lymphoma.

28 Jan 2016

Study leads to FDA approval of first immunotherapy for treatment of neuroblastoma

Building upon more than two decades of basic research conducted at Children's Hospital Los Angeles, Araz Marachelian, MD, of CHLA, and her colleagues at pediatric academic centers across the U. S., have shown that an immunotherapy that until now has only been available to patients enrolled in research studies, is equivalent to the product that has been manufactured for commercial use and can be made available to all patients.

28 Jan 2016

New machine-learning technique could be used to uncover previously unknown features of organisms

A powerful new machine-learning technique can be applied to large datasets in the biological sciences to uncover previously unknown features of organisms and their genes, according to a team led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

22 Jan 2016

Weekend junk food binges bad for your gut health

Yo-yoing between eating well during the week and bingeing on junk food over the weekend is likely to be just as bad for your gut health as a consistent diet of junk, new UNSW research suggests.

21 Jan 2016

Berlin researchers identify defects in myotubular myopathy

Tiny deviations in the body's cells can sometimes have severe consequences. Researchers from Berlin have discovered why cells from patients suffering from the rare muscular disease myotubular myopathy cannot function properly.

21 Jan 2016

Diabetes drug fails to show any benefit against pancreatic cancer

A diabetes drug that showed promise in previous studies as an anti-cancer treatment failed to show any benefit in a UNC Lineberger Comprehensive Cancer Center-led study that used pancreatic cancer tissue samples to test sensitivity to the drug.

20 Jan 2016

New blood biomarkers could lead to better evaluation of treatment for patients with PAH

New blood biomarkers reflecting vasoreactivity in lung blood vessels of patients with heart- and lung disease, can lead to simplified diagnostics and better evaluation of treatment for patients with the condition pulmonary arterial hypertension (PAH).

18 Jan 2016

Researchers reveal biological connection between obesity and colorectal cancer risk

Obesity has long been associated with increased risk of colorectal cancer, but the link has never been understood. Now, a research team led by investigators at Thomas Jefferson University has revealed the biological connection, and in the process, has identified an approved drug that might prevent development of the cancer.

18 Jan 2016

Pharmacology News and Research

Latest Pharmacology News and Research

Medical marijuana offers hope for kids with uncontrolled seizures

Implantable device could help deliver toxic cocktail of drugs directly to pancreatic tumors

Drinking extra 2 cups of coffee per day may reduce cirrhosis risk by 44%

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

HUYA, Eisai sign exclusive license agreement for HBI-8000 in Japan and other Asian countries

Framework for improving chemical hazard assessment without animals

HIV protein alters activity of networked neurons

FDA-approved blood pressure drug reduces cell damage linked to Alzheimer's disease

Researchers develop new painkiller as strong as morphine but not addictive

Researchers discover potential candidates for development of novel targeted therapies for blood cancers

Study leads to FDA approval of first immunotherapy for treatment of neuroblastoma

New machine-learning technique could be used to uncover previously unknown features of organisms

Weekend junk food binges bad for your gut health

Berlin researchers identify defects in myotubular myopathy

Diabetes drug fails to show any benefit against pancreatic cancer

New blood biomarkers could lead to better evaluation of treatment for patients with PAH

Researchers reveal biological connection between obesity and colorectal cancer risk

Discoveries could lead to development of novel therapies to prevent C. diff infection

Sage Analytics establishes distribution network in South America

New strategy may reduce growth of pancreatic cancers in patients with KRAS gene mutation

Industry Focus eBook - Pharmaceutical manufacturing (2nd edition) eBook

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Pharmacology News and Research

Latest Pharmacology News and Research

Industry Focus eBook - Pharmaceutical manufacturing (2nd edition) eBook

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Newsletters you may be interested in