Pharmacology News and Research

Latest Pharmacology News and Research

Research shows how scientists altered stem cells, triggered bone growth

Imagine you have a bone fracture or a hip replacement, and you need bone to form, but you heal slowly - a common fact of life for older people. Instead of forming bone, you could form fat. Researchers at the University of North Carolina School of Medicine may have found a way to tip the scale in favor of bone formation. They used cytochalasin D, a naturally occurring substance found in mold, as a proxy to alter gene expression in the nuclei of mesenchymal stem cells to force them to become osteoblasts (bone cells).

17 Nov 2015

Medicines do not degrade after being stored in space, shows study

The results of an opportunistic, pilot-scale study led by Virginia Wotring of the Center for Space Medicine and Department of Pharmacology at Baylor College of Medicine in the US suggest that medication degradation on the International Space Station (ISS) does not differ from what is typically seen on Earth.

11 Nov 2015

PAREXEL expands market access and clinical evidence services

PAREXEL International Corporation, a leading global biopharmaceutical services provider, today announced expanded evidence-based services for biopharmaceutical products.

10 Nov 2015

Addressing quality of life needs in prostate cancer: an interview with Professor Louis Denis

Modern patient-directed management is based on optimal, individual medical treatment and holistic personalised patient-centred care. This is certainly true in prostate cancer where most patients are over 60 years of age. They face a negative physical and functional impact from the diagnosis as well as from the treatment with emotional and social challenges.

4 Nov 2015

Advanced pain management fellowship prepares CRNAs to meet needs of Americans with chronic pain

As the first program of its kind in the United States, an advanced pain management fellowship prepares Certified Registered Nurse Anesthetists (CRNAs) with the pain management skills necessary to meet the needs of Americans with chronic pain, according to the American Association of Nurse Anesthetists.

4 Nov 2015

Scientists propose that Alzheimer's disease should be treated separately

Deciphering the mechanism that underlies the development of Alzheimer's disease in certain families but not in others, researchers at the Hebrew University of Jerusalem's Faculty of Medicine have proposed that the malady is actually a collection of diseases that probably should be treated with a variety of different approaches.

4 Nov 2015

New computational method helps predict adverse drug reaction better than traditional computing methods

A new integrated computational method helps predicting adverse drug reaction--which are often lethal--more reliably than with traditional computing methods. This improved ability to foresee the possible adverse effects of drugs may entail saving many lives in the future.

4 Nov 2015

Denator forms a new Scientific Advisory Board

Denator AB has announced that a new external expert advisory board has been formed. Karsten Fjärstedt, recently appointed as CEO comments, “It is a great honor for me to be entrusted to lead Denator forward in this new phase of development. With a pipeline of new exciting business opportunities and a strong Scientific Advisory Board (SAB) I am looking forward to realizing the full potential of the company technology”.

3 Nov 2015

Patients with Down syndrome face additional challenge of early-onset dementia

Individuals with Down syndrome who survive into adulthood face the additional challenge of early-onset dementia, in which toxic amyloid plaques build up in the brain. The condition is strikingly similar to Alzheimer's disease, and as new work led by researchers at the Lewis Katz School of Medicine at Temple University shows, dementia in Down syndrome involves defects in a regulatory enzyme known as γ-secretase activating protein (GSAP), which also happens to malfunction in Alzheimer's disease.

3 Nov 2015

New online tool may allow researchers explore formation of hair follicles

A new online database will empower researchers exploring how hair follicles and the surrounding skin develop, according to an article published recently in the journal Developmental Cell. The work is central to understanding the interactions between stem cells and their environment - or "niche cells" - during fetal development, and will specifically facilitate future attempts to make skin grafts with functional hair follicles or to regenerate lost hair in patients.

30 Oct 2015

New magnetic field delivery method could help treat traumatic brain injury

Treating traumatic brain injury (TBI) using stem cell therapy is an important area of current research. However, injecting stem cells into the central nervous system has serious drawbacks, including intracranial hemorrhage and cells failing to reach TBI-affected areas of the brain.

30 Oct 2015

New research shows that using e-cigarettes related to problematic drinking

Using e-cigarettes is related to problematic drinking, according to new research published in Addictive Behaviors. In a study involving around 1400 people, researchers also found that more women than men use e-cigarettes socially, opposite to patterns seen in regular cigarette smoking.

29 Oct 2015

IMBRUVICA (ibrutinib) wins Prix Galien USA 2015 Award in Best Pharmaceutical Agent category

Today, IMBRUVICA (ibrutinib) was awarded the prestigious Prix Galien USA 2015 Award in the category of Best Pharmaceutical Agent. The Prix Galien Award is considered to be the industry's highest accolade and recognizes the vital technical, scientific and clinical research skills necessary to develop medicines.

28 Oct 2015

Breakthrough research suggests that female sex hormone may save lives on the battlefield

Breakthrough research suggests a female sex hormone may be the key to saving lives on the battlefield, where between 2001 and 2011 more than 80 percent of potentially preventable U.S. war injury deaths resulted from blood loss.

22 Oct 2015

UF Health researcher reveals how betel nut's psychoactive chemical works in the brain

For hundreds of millions of people around the world, chewing betel nut produces a cheap, quick high but also raises the risk of addiction and oral cancer. Now, new findings by a University of Florida Health researcher reveal how the nut's psychoactive chemical works in the brain and suggest that an addiction treatment may already exist.

22 Oct 2015

Consuming high-fat diet may lead to anxiety and depression, cause measurable changes in the brain

A new study in mice reveals that increased body weight and high blood sugar as a result of consuming a high-fat diet may cause anxiety and depressive symptoms and measurable changes in the brain.

20 Oct 2015

Discovery may provide noninvasive approach to assessing toxic effects of anesthetic agents in children

Could looking at the eyes provide a new way of studying how anesthesia affects the developing brain? The retinas of immature mice exposed to one widely used general anesthetic show evidence of "programmed cell death," or apoptosis, reports a study in Anesthesia & Analgesia.

19 Oct 2015

New research shows nicotine increases codeine-induced analgesia

According to new research in rat models, nicotine use over time increases the speed that codeine is converted into morphine within the brain, by increasing the amount of a specific enzyme. It appears smokers' brains are being primed for a bigger buzz from this common pain killer - which could put them at a higher risk for addiction, and possibly even overdose.

19 Oct 2015

New synthetic process helps study key molecule involved in diabetes, inflammation, aging

A synthetic process developed at Yale University will allow researchers to study a key molecule involved in diabetes, inflammation, and human aging.

16 Oct 2015

Study suggests combination of MMF and CNIs can protect against rare lymphoma

A study led by Johns Hopkins researchers has linked the immunosuppressive drug mycophenolate mofetil (MMF) to an increased risk of central nervous system (CNS) lymphoma in solid organ transplant patients.

16 Oct 2015

Pharmacology News and Research

Latest Pharmacology News and Research

Research shows how scientists altered stem cells, triggered bone growth

Medicines do not degrade after being stored in space, shows study

PAREXEL expands market access and clinical evidence services

Addressing quality of life needs in prostate cancer: an interview with Professor Louis Denis

Advanced pain management fellowship prepares CRNAs to meet needs of Americans with chronic pain

Scientists propose that Alzheimer's disease should be treated separately

New computational method helps predict adverse drug reaction better than traditional computing methods

Denator forms a new Scientific Advisory Board

Patients with Down syndrome face additional challenge of early-onset dementia

New online tool may allow researchers explore formation of hair follicles

New magnetic field delivery method could help treat traumatic brain injury

New research shows that using e-cigarettes related to problematic drinking

IMBRUVICA (ibrutinib) wins Prix Galien USA 2015 Award in Best Pharmaceutical Agent category

Breakthrough research suggests that female sex hormone may save lives on the battlefield

UF Health researcher reveals how betel nut's psychoactive chemical works in the brain

Consuming high-fat diet may lead to anxiety and depression, cause measurable changes in the brain

Discovery may provide noninvasive approach to assessing toxic effects of anesthetic agents in children

New research shows nicotine increases codeine-induced analgesia

New synthetic process helps study key molecule involved in diabetes, inflammation, aging

Study suggests combination of MMF and CNIs can protect against rare lymphoma

Industry Focus eBook - Pharmaceutical manufacturing (2nd edition) eBook

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Pharmacology News and Research

Latest Pharmacology News and Research

Industry Focus eBook - Pharmaceutical manufacturing (2nd edition) eBook

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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