Psoriasis News and Research

Latest Psoriasis News and Research

Extended steroid treatment fails to reduce pediatric nephrotic relapse

Study findings indicate that extending initial prednisolone treatment durations in patients with pediatric nephrotic syndrome from 3 to 6 months without increasing the overall dose does not reduce the number of relapses.

22 Dec 2012

French method successful for clubfoot

Researchers have demonstrated the efficacy of the “French” functional method for correcting congenital idiopathic clubfoot, with the majority of patients achieving a good result, often without surgery.

20 Dec 2012

Positive top-line results from Idera’s IMO-3100 Phase 2a trial on plaque psoriasis

Idera Pharmaceuticals today announced that 48% of patients with moderate-to-severe plaque psoriasis (12 of 25) treated with IMO-3100, a selective antagonist of Toll-like Receptors (TLRs) 7 and 9, demonstrated improvements in Psoriasis Area Severity Index (PASI) scores of 35% to 90% from baseline at the completion of a randomized, double-blind, placebo-controlled Phase 2a clinical trial of two dose levels of IMO-3100 administered for four weeks, with a four-week follow-up period.

20 Dec 2012

Researchers reveal role of dendritic cells in Type 1 diabetes

The researchers reveal the role of the innate immune cells, especially the dendritic cells, that cause the activation of the killer T-lymphocytes whose action is directed against the p pancreatic cells. The results obtained in mice make it possible to consider new ways of regulating the auto-immune reaction generated by the innate immune cells.

20 Dec 2012

Umbilical cord stem cell therapy shows promise in infant BPD

Researchers have successfully used human umbilical cord stem cells to partially prevent damage and restore lung structure and function in an experimental animal model of bronchopulmonary dysplasia.

19 Dec 2012

Amgen expected to enter a guilty plea to unspecified charges

The biotech giant is expected to plead guilty in a New York federal court criminal case. Some reports suggest the charges relate to "misbranding" -- which refers to the promotion of drugs for uses that have not gained the Food and Drug Administration's approval.

19 Dec 2012

Ceramic-on-ceramic hips good option for juvenile arthritis

Study results suggest that ceramic-on-ceramic artificial hip joints offer a better medium-term prognosis than metal- or ceramic-on-polyethylene joints for children with juvenile idiopathic arthritis.

18 Dec 2012

Mother–infant pairs admitted to ICU have poor outcomes

Mother–baby pairs with co-admission to intensive care units after delivery are more likely to experience separation due to interfacility transfer, and have higher mortality rates, than pairs in which either mothers or babies are admitted, show study results.

17 Dec 2012

Cleft palate children need regular hearing check-ups

Children with cleft palate require regular audiologic and otologic follow-up to ensure their management is appropriate and timely, say researchers.

12 Dec 2012

Ultrasonography effective for diagnosing childhood pneumonia

Point-of-care ultrasound scanning can be used to diagnose pneumonia accurately in children and young people, show study findings.

11 Dec 2012

Contrast agent ‘not recommended’ in premature neonates

Premature neonates who are given oral Gastrografin immediately after birth do not pass meconium more quickly than others, study findings suggest.

10 Dec 2012

Mutations signaling poor neuroblastoma prognosis identified

Children with neuroblastoma who have mutations in the ARID1A and ARID1B genes in their tumors have a poor prognosis compared with those without these alterations, show study findings.

4 Dec 2012

Stem cells give insight into path of cytomegalovirus infection

Primitive human stem cells are resistant to human cytomegalovirus, say researchers who believe this finding could provide further insight into disease pathology.

3 Dec 2012

Nontraditional velopharyngoplasty predictor unveiled

The necessity of subsequent velopharyngoplasty does not depend on the time of soft palate closure and type of cleft, say researchers.

28 Nov 2012

FDA grants final approval to Cobrek’s generic Luxiq foam NDA for treatment of scalp psoriasis

Perrigo Company today announced that its partner, Cobrek Pharmaceuticals, Inc., received final approval from the U.S. Food and Drug Administration for its Abbreviated New Drug Application (ANDA) for betamethasone valerate foam 0.12%, the generic equivalent of Luxiq Foam.

28 Nov 2012

Ultrasound puts emergency lines in the right place

Training emergency department staff in use of ultrasound to guide difficult peripheral intravenous catheter placement appears to reduce the unnecessary use of central venous lines, a study suggests.

27 Nov 2012

Child injury fear may take the bounce out of the castle

Injuries sustained while playing on inflatable toys such as bouncy castles have increased at a rapid rate over the last two decades.

26 Nov 2012

$Neonatal history must be taken in ex-preterms with fractures$

Neonatal history must be taken in ex-preterms with fractures

Researchers say that a neonatal history must be taken in all ex-preterm infants with rib fractures.

26 Nov 2012

New therapeutic approach for preventing Alzheimer's disease

Pathological changes typical of Alzheimer's disease were significantly reduced in mice by blockade of an immune system transmitter. A research team from Charité - Universitätsmedizin Berlin and the University of Zurich has just published a new therapeutic approach in fighting Alzheimer's disease in the current issue of Nature Medicine. This approach promises potential in prevention, as well as in cases where the disease has already set in.

26 Nov 2012

Turning off particular cytokines reduces Alzheimer's typical amyloid-- deposits in mice

Alzheimer's disease is one of the most common causes of dementia. In Germany and Switzerland alone, around 1.5 million people are affected, and forecasts predict a doubling of the number of patients worldwide within the next 20 years. The accumulation of particular abnormal proteins, including amyloid-- (Aβ) among others, in patients' brains plays a central role in this disease.

26 Nov 2012