Rotavirus is the most common cause of severe diarrhea among children, resulting in the hospitalization of approximately 55,000 children each year in the United States and the death of over 600,000 children annually worldwide. The incubation period for rotavirus disease is approximately 2 days. The disease is characterized by vomiting and watery diarrhea for 3 - 8 days, and fever and abdominal pain occur frequently. Immunity after infection is incomplete, but repeat infections tend to be less severe than the original infection.
Rotavirus Structure and Classification
Rotavirus is an acute infection that can have lethal consequences if left untreated. This article describes the structure and classification of the virus.
A group of researchers at Kannur University reviewed selected papers and in silico work on potential drug leads that could be used to manage COVID-19.
Inoculation with live attenuated vaccines (LAV) such as those used against TB, polio or measles can stimulate the immune system to provide protection against other infectious diseases, including COVID-19, says a new study.
\With the onset of the coronavirus disease 2019 (COVID-19) pandemic, hundreds of millions of people became infected worldwide, including thousands of pregnant women near term. The question of vertical transmission to the infant via the placenta or breast milk was very real, leading to a near-total ban on breastfeeding in this group.
The interiors of nonflowering trees such as pine and ginkgo contain sapwood lined with straw-like conduits known as xylem, which draw water up through a tree's trunk and branches.
In the paper published in the journal Frontiers in Immunology, the researchers noted that since both the respiratory tract and the gastrointestinal mucosa are affected in COVID-19, it is possible that adjunctive therapies that modulate the gut-lung axis.
The study began with the generation of recombinant (r)SA11 rotaviruses, into which segment 7 modified RNAs were introduced. These encoded sequences for the non-structural protein NSP3 and some parts of the viral spike.
As antibiotic use grows in lower-income countries so does antibiotic resistance, says report.
Researchers report on a Chicken-derived antibody against SARS-CoV-2, offering preliminary data on a potential therapeutic for COVID-19 warranting further research.
A new study describes the antiviral activity of oxysterols, or oxidized cholesterol derivatives, against SARS-CoV-2. These occur in nature, and are not only involved in lipid signaling pathways that modulate a host of processes within the body, including the immune response and lipid homeostasis.
A year ago, while many Americans were finishing their holiday shopping and finalizing travel plans, doctors in Wuhan, China, were battling a mysterious outbreak of pneumonia with no known cause.
UniSA researchers are evaluating a new vaccination education initiative - the COVID-19 Peer Hub - to help immunization and public health professionals to tackle the emerging dangers of vaccine hesitancy amid the pandemic.
Rotavirus is a major cause of diarrhea and vomiting, especially in children, that results in approximately 128,000 deaths annually.
The White House and many Americans have pinned their hopes for defeating the COVID-19 pandemic on a vaccine being developed at "warp speed." But some scientific experts warn they're all expecting too much, too soon.
Rotavirus (RV) is an extremely contagious viral infection and the most common cause of diarrhea in infants and children worldwide.
An exciting, 'tour-de-force' paper by researchers from the Massachusetts Institute of Technology describes de novo discovery of high-affinity peptide binders for SARS-CoV-2 spike glycoprotein, which opens the door for the development of rapid viral identification or conjugates for virus-directed delivery of therapeutics.
Neuroinformatics scientists at Osnabrück University and data specialists at Forschungszentrum Jülich are releasing new model results daily to forecast COVID-19 infections.
Researchers in the United States and Japan have conducted a study suggesting that a commonly occurring genetic variant influences susceptibility to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).
Many studies on the containment of the ongoing COVID-19 pandemic have dealt with the possible role of wastewater in predicting and detecting future outbreaks and understanding the epidemiology of COVID-19 disease. A recent study published on the preprint server medRxiv* in September 2020 shows that solid waste in sewage is a better substrate for testing than influent.
The COVID-19 pandemic has focused, yet again, intense research interest on coronaviruses, due to the high toll the novel coronavirus SARS-CoV-2 has taken on human life, health, economic well-being, and social activity. A recent paper published on the server Preprints in September 2020 reviews what is known about this viral infection in water life.
Immunizing pregnant women with a potential vaccine against RSV could prevent the most common cause of pneumonia in their babies.