Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

High prevalence of cross-reactive anti-SARS-CoV-2 antibodies in sub-Saharan Africa

A recent study published in the International Journal of Infectious Diseases has explained the lower prevalence of coronavirus disease 2019 (COVID-19) in sub-Saharan Africa compared to that in the US, Europe, and Asia.

15 Nov 2020

Ultrasound reveals a possible role of SARS‐CoV‐2 in acute testicular infection

A single-center study from Wuhan in China presents ultrasound imaging evidence supporting the notion that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause infection of the testis or epididymis – and put patients at risk for further complications. The paper can be found in the Journal of Ultrasound in Medicine.

15 Nov 2020

Novel mutations in SARS-CoV-2 may explain high pathogenicity of COVID-19

Researchers in Korea and the United States have identified novel genetic variants that demonstrate the active mutational progression of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

15 Nov 2020

SARS-CoV-2 immunity may last over six months through antibody evolution and B cell memory

With the coronavirus disease 2019 (COVID-19) pandemic infecting over 52.7 million people around the world, and killing over 1.2 million, a large amount of research has tried to better understand immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes COVID-19.

15 Nov 2020

Antimalarials could disrupt SARS-CoV-2’s Nsp1 translation termination

A research team from the Engelhardt Institute of Molecular Biology in Russia have shown that Nsp1 – a non-structured protein present in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen – stimulates translation termination in the stop codon recognition stage. Studying and developing drugs that compete with Nsp1 for binding with the termination complex could therefore be a potential strategy for fighting against coronavirus disease 2019 (COVID-19).

15 Nov 2020

Transmission of SARS-CoV-2 among US marine recruits after quarantine: A case study

A team of researchers at the Naval Medical Research Center, Silver Spring, USA, analyzed the risk of transmission of SARS-CoV-2 among marine recruits. Their study titled, “SARS-CoV-2 Transmission among Marine Recruits during Quarantine,” was published in the latest issue of the New England Journal of Medicine.

15 Nov 2020

Some people had non-neutralizing antibodies against SARS-CoV-2 prior to COVID-19

A recent study examined several medical records and found that while past human coronavirus exposures are not linked to decreased SARS-CoV-2 infections, they are associated with reduced COVID-19 severity.

12 Nov 2020

250,000 cases of child abuse or neglect may have gone unreported in U.S. COVID pandemic

A recent study published in the journal Child Abuse and Neglect has reported that the number of child maltreatment reports and child welfare interventions decreased significantly in New York City during the initial phase of the coronavirus disease 2019 (COVID-19) pandemic.

12 Nov 2020

Mink farms potential viral reservoirs for SARS-CoV-2

A new study published in the journal Science in November 2020 describes the probable transmission of the virus between farmed minks and humans working on the mink farm, even with biosecurity measures in place and the culling of infected farms as soon as an infection is reported.

12 Nov 2020

Bispecific sybodies show potential against SARS-CoV-2

As the search for effective antivirals against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues, a new study published on the preprint bioRxiv in November 2020 discusses the role of synthetic nanobodies or sybodies in neutralizing the virus by binding to its receptor-binding domain (RBD) on the spike protein.

12 Nov 2020

Promising SARS-CoV-2 N epitope for more accurate diagnostic and surveillance antibody testing

A new study published on the preprint server bioRxiv in November 2020 describes the virus's N protein as a promising epitope for serology.

12 Nov 2020

SARS-CoV-2-induces temporary loss of smell in mice

Now, a new study published on the preprint server bioRxiv in November 2020 presents the onset of olfactory dysfunction (loss of smell) in mice infected with the virus, examining this process at the cellular level. In doing so, this study throws more light on this curious symptom and COVID-19’s manifestations outside the lungs.

12 Nov 2020

Modeling suggests lower COVID-19 cases in Lombardy's second wave

Researchers found a negative association between the number of excess deaths during the first wave of the epidemic and the number of second-wave cases. This could be because of both a sort of herd immunity and changes in behavioral response.

12 Nov 2020

Convalescent plasma in COVID-19 can be effective, especially early in disease

A team of researchers in the United States have conducted an extensive literature review looking at the usage of convalescent plasma from recovered COVID-19 patients to treat those with an impaired immune system. Their study, titled “Therapeutic use of convalescent plasma in COVID-19 patients with immunodeficiency: A systematic review,” has been released on medRxiv*, the preprint server.

12 Nov 2020

Researchers assess risks posed by SARS-CoV-2 to Antarctica wildlife

Researchers have assessed risks posed by the ongoing COVID-19 pandemic on Antarctica wildlife.

12 Nov 2020

Peptide-conjugated morpholino oligomers effectively inhibit SARS-CoV-2 in vero cells

The hunt for antivirals has reached an unprecedented pace in light of the coronavirus 2019 (COVID-19) pandemic. The causal agent for this disease – severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – has already infected over 52 million people worldwide, and has subsequently claimed over 1.3 million lives. However, among the innumerable promising drug candidates that help battle the virus and mitigate its damage, none have yet made it to the clinic.

12 Nov 2020

"Cat's claw" extract inhibits replication of SARS-CoV-2 in vitro

Researchers in Columbia and Peru have shown that Uncaria tomentosa – a woody vine native to South America known of as "Cat's claw" – exerts in vitro antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

12 Nov 2020

Disinfectants with "virucidal activity against enveloped viruses" effective against SARS-CoV-2

A recent study demonstrated that two commercially available surface disinfectant formulations and one hand disinfection formulation that claim "virucidal activity against enveloped viruses" are effective in inactivating the SARS-CoV-2 virus. Their study has been published on the preprint server bioRxiv.

11 Nov 2020

Researchers identify acrylamides that inhibit SARS-CoV-2 main protease

A new study in the preprint server bioRxiv published in November 2020 describes the discovery of acrylamide fragments that can effectively disable key enzymes in both the hand, foot and mouth virus and SARS-CoV-2 virus.

11 Nov 2020

Human coronaviruses cause processing body loss

Researchers continue to expand their knowledge of coronaviruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen. Now, a new study published on the preprint server bioRxiv in November 2020 describes a vital mechanism whereby the novel SARS-CoV-2 pathogen can restrict the human host response. In doing so, the study explores how this novel feature of SARS-CoV-2 works and how it results in a reshaping of the human host's immune response.

11 Nov 2020

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

High prevalence of cross-reactive anti-SARS-CoV-2 antibodies in sub-Saharan Africa

Ultrasound reveals a possible role of SARS‐CoV‐2 in acute testicular infection

Novel mutations in SARS-CoV-2 may explain high pathogenicity of COVID-19

SARS-CoV-2 immunity may last over six months through antibody evolution and B cell memory

Antimalarials could disrupt SARS-CoV-2’s Nsp1 translation termination

Transmission of SARS-CoV-2 among US marine recruits after quarantine: A case study

Some people had non-neutralizing antibodies against SARS-CoV-2 prior to COVID-19

250,000 cases of child abuse or neglect may have gone unreported in U.S. COVID pandemic

Mink farms potential viral reservoirs for SARS-CoV-2

Bispecific sybodies show potential against SARS-CoV-2

Promising SARS-CoV-2 N epitope for more accurate diagnostic and surveillance antibody testing

SARS-CoV-2-induces temporary loss of smell in mice

Modeling suggests lower COVID-19 cases in Lombardy's second wave

Convalescent plasma in COVID-19 can be effective, especially early in disease

Researchers assess risks posed by SARS-CoV-2 to Antarctica wildlife

Peptide-conjugated morpholino oligomers effectively inhibit SARS-CoV-2 in vero cells

"Cat's claw" extract inhibits replication of SARS-CoV-2 in vitro

Disinfectants with "virucidal activity against enveloped viruses" effective against SARS-CoV-2

Researchers identify acrylamides that inhibit SARS-CoV-2 main protease

Human coronaviruses cause processing body loss

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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