Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Flexibility of glycosylated membrane-bound ACE2 suggests mechanical energy source in opening of SARS-CoV-2 spike

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17 Sep 2020

Could pineapples be a new weapon against COVID-19?

Results of a recent research endeavor from the United States indicate that bromelain or bromelain rich pineapple stem may be utilized as an antiviral agent against coronavirus disease (COVID-19), but also for potential future coronavirus outbreaks. This exciting paper is currently available on the bioRxiv preprint server.

17 Sep 2020

LOX-1-immature neutrophils may help identify COVID-19 patients at risk of thrombosis complication

To predict severe outcome in COVID-19 patients, innate immune cellular signals are analyzed, identifying two novel neutrophil subsets: LOX-1- and CD123-expressing CD10-CD64+. Thromboembolic events correlated with high LOX-1 immature neutrophils – a potential prognostic signature.

17 Sep 2020

COVID-19 could be diagnosed using stroke scans

New research from King's College London has found that COVID-19 may be diagnosed on the same emergency scans intended to diagnose stroke.

17 Sep 2020

Testing settled solids in sewage for SARS-CoV-2 more sensitive approach than testing influent

Many studies on the containment of the ongoing COVID-19 pandemic have dealt with the possible role of wastewater in predicting and detecting future outbreaks and understanding the epidemiology of COVID-19 disease. A recent study published on the preprint server medRxiv* in September 2020 shows that solid waste in sewage is a better substrate for testing than influent.

17 Sep 2020

Ceftazidime flagged as a potential inhibitor of the SARS-COV-2 virus

After screening more than 3,500 FDA-approved drugs and small molecules, researchers at the Chinese Academy of Sciences found that ceftazidime, an antibiotic approved for use in treating pneumonia, binds to the receptors that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to in human cells.

17 Sep 2020

Optimal antibody combinations and Fc binding inhibit SARS-CoV-2 in vivo

A recent study by researchers at the University of North Carolina at Chapel Hill and The Rockefeller University and published on the preprint server bioRxiv in September 2020 shows that a combination of neutralizing antibodies with intact Fc effector function can effectively reduce the viral load and prevent infection.

17 Sep 2020

Seropositive partners increase risk of COVID-19 but not obstetric complications in pregnant women

While earlier studies have shown the significance of serological testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in pregnant women, their partners have largely been excluded. Now, a new Danish study published on the preprint server medRxiv in September 2020 reports the impact of serologic testing in both pregnant women and their partners, as well as their newborns.

17 Sep 2020

Higher viral loads can increase mortality rate in patients hospitalized with COVID-19 and cancer

Higher viral loads are associated with a greater risk of death among cancer and non-cancer patients hospitalized with coronavirus disease 2019 (COVID-19), researchers report September 15 in the journal Cancer Cell.

17 Sep 2020

Anti-CD73 molecule CPI-006 activates B cell responses to SARS-CoV-2

As the COVID-19 pandemic continues to cause an immense impact across many parts of the world, the role played by immune responses is becoming more evident every day. A recent funded paper published on the preprint server medRxiv* in September 2020 reports the initiation of a Phase I trial of a drug that increases antibody and cell-mediated immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

New York City’s initial lockdown reduced coronavirus spread by 70 percent, study says

A team of researchers at Columbia University and the New York City Department of Health and Mental Hygiene have shown that this move by the government was effective in reducing the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19).

16 Sep 2020

CDC reports low mortality among children from COVID-19, but minorities are at risk

In the United States, the U.S. Centers for Disease Control and Prevention (CDC) reports 121 deaths among young people under the age of 21. Children from ethnic and racial minorities, those with underlying medical conditions, and in this age group, those between the ages of 18 and 20 are more likely to die from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19.

16 Sep 2020

SARS-CoV-2 with D614G mutation is prevalent in central India

A team of scientists at the Defence Research and Development Establishment, India, reveals that there are multiple viral introduction events in central India, and SARS-CoV-2 with D614G mutation is the prevalently circulating strain.

16 Sep 2020

Self-assembling nanoparticles as a way towards next-generation COVID-19 vaccines

In a promising study by US researchers, the receptor-binding domain (RBD) and stabilized spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were displayed on nanoparticles as vaccine antigens and elicited potent immune responses.

16 Sep 2020

Low birth weight appears to increase risk of severe COVID-19 in adults

Researchers in Barcelona, Spain have conducted a study showing that low birth weight seems to be an independent risk factor for severe illness among non-elderly adults with coronavirus disease 2019 (COVID-19).

16 Sep 2020

Candidate monoclonal antibody shows hope as COVID-19 treatment

Researchers in the United States have described the effectiveness of a candidate monoclonal antibody currently being evaluated in a Phase 1 trial as a therapy for coronavirus disease 2019 (COVID-19) and its causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Sep 2020

New images capture startlingly high SARS-CoV-2 viral loads

Now, a team of scientists from the University of North Carolina at Chapel Hill School of Medicine produced striking images in respiratory tract cultures of the infectious form of the SARS-CoV-2 produced by infected epithelial cells.

16 Sep 2020

SARS-CoV-2 infection severity linked to superior humoral immunity against the S-protein

In a recent bioRxiv* preprint paper, Jenna J. Guthmiller et al., focus on the acute infection of SARS-CoV-2 and observe that the humoral immunity is distinctive with the infection stage and viral antigens.

16 Sep 2020

Microfiber pillows could harbor SARS-CoV-2 particles

A new study by researchers at the Department of Environmental Science and Engineering, Xi'an Jiaotong University, China and published in the journal Ecotoxicology and Environmental Safety suggests that respiratory pathogens can not only fall on the fabric covers but can also penetrate the outer cover and go into the microfiber stuffing.

16 Sep 2020

SARS-CoV-2 N protein forms biomolecular condensates with viral RNA

Now, a study by researchers from the University of California has shown that the N protein forms biomolecular condensates with the viral RNA in both in vitro and in vivo studies. The research titled, ‘SARS CoV-2 nucleocapsid protein forms condensates with viral genomic RNA’, was published on the preprint server bioRxiv on September 14th, 2020.

15 Sep 2020

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Flexibility of glycosylated membrane-bound ACE2 suggests mechanical energy source in opening of SARS-CoV-2 spike

Could pineapples be a new weapon against COVID-19?

LOX-1-immature neutrophils may help identify COVID-19 patients at risk of thrombosis complication

COVID-19 could be diagnosed using stroke scans

Testing settled solids in sewage for SARS-CoV-2 more sensitive approach than testing influent

Ceftazidime flagged as a potential inhibitor of the SARS-COV-2 virus

Optimal antibody combinations and Fc binding inhibit SARS-CoV-2 in vivo

Seropositive partners increase risk of COVID-19 but not obstetric complications in pregnant women

Higher viral loads can increase mortality rate in patients hospitalized with COVID-19 and cancer

Anti-CD73 molecule CPI-006 activates B cell responses to SARS-CoV-2

New York City’s initial lockdown reduced coronavirus spread by 70 percent, study says

CDC reports low mortality among children from COVID-19, but minorities are at risk

SARS-CoV-2 with D614G mutation is prevalent in central India

Self-assembling nanoparticles as a way towards next-generation COVID-19 vaccines

Low birth weight appears to increase risk of severe COVID-19 in adults

Candidate monoclonal antibody shows hope as COVID-19 treatment

New images capture startlingly high SARS-CoV-2 viral loads

SARS-CoV-2 infection severity linked to superior humoral immunity against the S-protein

Microfiber pillows could harbor SARS-CoV-2 particles

SARS-CoV-2 N protein forms biomolecular condensates with viral RNA

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

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