T Cell News and Research

Latest T Cell News and Research

Penn researchers report results of CAR therapy trial in brain cancer patients

Immune cells engineered to seek out and attack a type of deadly brain cancer known as glioblastoma (GBM) were found to have an acceptable safety profile and successfully migrate to and infiltrate tumors, researchers from Penn Medicine and Harvard University reported at the AACR Annual Meeting 2016.

19 Apr 2016

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Cancer cells often devise ways to survive even in the presence of toxic chemotherapy. Now, a research team led by investigators at Beth Israel Deaconess Medical Center has found a way to attack a process that tumor cells use to escape the effects of standard cancer drugs. The discovery is published online today in the journal Nature Cell Biology.

19 Apr 2016

Transplanted human islets prevent hypoglycemic events in Type 1 diabetes patients

Northwestern Medicine researchers are co-investigators in a breakthrough clinical trial that found transplanted human islets prevent hypoglycemic events and provide excellent glycemic control for patients with Type 1 diabetes with severe hypoglycemia.

19 Apr 2016

Scientists discover new diagnostic marker for liver cancer

Scientists may have discovered a significant new diagnostic marker for liver cancer, according to a paper published in the April 18 online issue of Nature Cell Biology.

19 Apr 2016

UNC scientists develop new optogenetic tool to study function of different proteins

Scientists at the University of North Carolina School of Medicine have developed a way to embed light-responsive switches into proteins so that researchers can use lasers to manipulate protein movement and activity within living cells and animals.

19 Apr 2016

Researchers develop new method for identifying DNA mutations in single cancer cell

Researchers at The University of Texas MD Anderson Cancer Center have announced a new method for detecting DNA mutations in a single cancer cell versus current technology that analyzes millions of cells which they believe could have important applications for cancer diagnosis and treatment. The results are published in the April 18 online issue of Nature Methods.

19 Apr 2016

Researchers devise method to stably internalize chemotherapy loaded microparticles into prostate cells

A collaborative Brigham and Women's Hospital and Johns Hopkins University co-led team has found proof-of-concept evidence for a potential cancer treatment that leverages microparticles and mesenchymal stem cells.

19 Apr 2016

Oxidized mitochondrial nucleoids released from neutrophils may contribute to SLE pathogenesis

Researchers at the Baylor Institute for Immunology Research have discovered that the neutrophils of systemic lupus erythematosus (SLE) patients release oxidized DNA from their mitochondria that can stimulate an unwanted immune response.

19 Apr 2016

Researchers successfully use stem cells to promote nerve fibre regeneration after spinal cord injuries

Researchers from Hokkaido University in Japan together with an international team of scientists implanted specialized embryonic stem cells into the severed spinal cords of rats.

19 Apr 2016

NanoString launches new nCounter Vantage assays that power 3D Biology experiments in cancer research

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced the introduction of nCounter Vantage, a portfolio of assays that power 3D Biology™ experiments in cancer research, including immuno-oncology.

From NanoString Technologies 19 Apr 2016

Researchers use BMG LABTECH's microplate readers to measure binding events in kinetic over minutes

Single reading events of a signaling molecule at a given time should no longer be considered as the only insightful indicator to predict the usefulness of a new drug candidate.

From BMG LABTECH GmbH 19 Apr 2016

Reducing hair loss during chemotherapy: an interview with Richard Paxman

The basic principle of chemotherapy is to damage the mitotic and metabolic processes in the cancer cells. The chemotherapy doesn't just target the cancer cells, it also targets the healthy cells, specifically ones that are rapidly dividing - our hair follicles are also rapidly dividing. We see damage to those hair cells, which then causes the hair to fall out.

From Paxman 19 Apr 2016

Researchers reveal how relatively unknown pathogen led to current Zika outbreak

An analysis comparing the individual differences between over 40 strains of Zika virus (30 isolated from humans, 10 from mosquitoes, and 1 from monkeys) has identified significant changes in both amino acid and nucleotide sequences during the past half-century.

18 Apr 2016

Studies confirm benefit of plasma genotyping to predict treatment outcomes for NSCLC patients

The benefit of plasma genotyping to predict treatment benefit in patients with non-small-cell lung cancer (NSCLC) is confirmed in three studies presented today at the European Lung Cancer Conference (ELCC) 2016 in Geneva, Switzerland. Researchers however warned that plasma tests are unlikely to fully replace tissue biopsies.

18 Apr 2016

Hold position of RBC affects tensile test results

A group of researchers from Japan has examined how the hold position of a red blood cell affects its mechanical characteristics in tensile tests.

18 Apr 2016

Irvine neurobiologists find new way to change damaging course of Huntington disease

A study appearing April 14 in the journal Neuron suggests there may be a new way to change the damaging course of Huntington disease.

18 Apr 2016

Noise in concentration of vitamin A derivative RA can lead to disruptions in brain development

Using cutting-edge imaging technology, University of California, Irvine biologists have determined that uncontrolled fluctuations (known at "noise) in the concentration of the vitamin A derivative Retinoic acid (RA) can lead to disruptions in brain organization during development.

18 Apr 2016

Medi-551 antibody treatment decreases number of cancer stem cells by half in multiple myeloma patients

An experimental antibody treatment decreased by half the number of cancer stem cells that drive the growth of tumors in nearly all patients with multiple myeloma, a cancer of the bone marrow and bone tissue, according to results of a preliminary clinical trial led by Johns Hopkins Kimmel Cancer Center scientists.

18 Apr 2016

First-ever nivolumab drug trial for rare, malignant SCCA shows positive results

A rare malignancy known as squamous cell carcinoma of the anal canal (SCCA) is on the increase, and now researchers have reported results of the first-ever phase II clinical trial results for treatment with the immunotherapy drug nivolumab.

18 Apr 2016

LOXO-101 drug shows efficacy with tumor regression in varied types of genetically defined cancer

A phase I study of the drug LOXO-101 appears to significantly reduce tumors in patients with varied types of genetically defined cancer, according to a study led by The University of Texas MD Anderson Cancer Center.

18 Apr 2016

T Cell News and Research

Latest T Cell News and Research

Penn researchers report results of CAR therapy trial in brain cancer patients

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Transplanted human islets prevent hypoglycemic events in Type 1 diabetes patients

Scientists discover new diagnostic marker for liver cancer

UNC scientists develop new optogenetic tool to study function of different proteins

Researchers develop new method for identifying DNA mutations in single cancer cell

Researchers devise method to stably internalize chemotherapy loaded microparticles into prostate cells

Oxidized mitochondrial nucleoids released from neutrophils may contribute to SLE pathogenesis

Researchers successfully use stem cells to promote nerve fibre regeneration after spinal cord injuries

NanoString launches new nCounter Vantage assays that power 3D Biology experiments in cancer research

Researchers use BMG LABTECH's microplate readers to measure binding events in kinetic over minutes

Reducing hair loss during chemotherapy: an interview with Richard Paxman

Researchers reveal how relatively unknown pathogen led to current Zika outbreak

Studies confirm benefit of plasma genotyping to predict treatment outcomes for NSCLC patients

Hold position of RBC affects tensile test results

Irvine neurobiologists find new way to change damaging course of Huntington disease

Noise in concentration of vitamin A derivative RA can lead to disruptions in brain development

Medi-551 antibody treatment decreases number of cancer stem cells by half in multiple myeloma patients

First-ever nivolumab drug trial for rare, malignant SCCA shows positive results

LOXO-101 drug shows efficacy with tumor regression in varied types of genetically defined cancer

Immunology eBook

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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