T Cell News and Research

Latest T Cell News and Research

Bacteroidia pilins prevalent in human gut and mouth form new type of pili to cling to hosts

Many bacteria interact with their environment through hair-like structures known as pili, which attach to and help mediate infection of host organisms, among other things. Now a U.S.-Japanese research team, including scientists from the Department of Energy's SLAC National Accelerator Laboratory, has discovered that certain bacteria prevalent in the human gut and mouth assemble their pili in a previously unknown way - information that could potentially open up new ways of fighting infection.

12 Apr 2016

Six newly identified proteins may help potentially unlock new insights into aging-related diseases

A group of six newly discovered proteins may help to divulge secrets of how we age, potentially unlocking new insights into diabetes, Alzheimer's, cancer, and other aging-related diseases.

12 Apr 2016

Distribution of c-Myc protein during asymmetric cell division influences fate, roles of activated T cells

The fates of immune cells can be decided at the initial division of a cell. Researchers at St. Jude Children's Research Hospital have discovered that the production of daughter cells with different roles in the immune system is driven by the lopsided distribution of the signaling protein c-Myc. Nudging c-Myc in one direction or the other could make vaccines more effective or advance immunotherapies for cancer treatment. The research appears online today in the scientific journal Nature.

12 Apr 2016

Cell-signaling protein holds key to understanding autoantibody formation in lupus patients

A signaling molecule called interferon gamma could hold the key to understanding how harmful autoantibodies form in lupus patients. The finding could lead to new treatments for the chronic autoimmune disease, said researchers at Penn State College of Medicine.

12 Apr 2016

Alternative splicing regulates MALT1 protein to have stronger or weaker effect on immune system

The protein MALT1 is an important switch in immune cells and affects their activity. Researchers at Helmholtz Zentrum München report in 'Nature Communications' that this activation is not always equally strong. Through alternative splicing, two variants of the protein may arise which have a stronger or weaker effect on the immune system. Understanding this process is important for the pharmacological use of MALT1.

12 Apr 2016

Abnormally active Rab5 protein leads to early development of neurodegenerative disease

Writing in the April 11 issue of The Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells are linked to axonal dysfunction and degeneration of neurons in Alzheimer's disease (AD) and Down syndrome (DS).

12 Apr 2016

Researchers investigate biochemical, physiological characteristics of facial and extraocular muscles

In a new study, a research team at Basel University Hospital in Switzerland investigates the biochemical and physiological characteristics of orbicularis oculi, a group of facial muscles that control the eyelids and are selectively spared or involved in different neuromuscular disorders. What they found also helps to explain why another set of muscles—the extraocular muscles that control the movement of the eye—are not affected by Duchenne muscular dystrophy, congenital muscular dystrophy, and aging.

12 Apr 2016

Leica Microsystems launches new camera for imaging live cells under near-native conditions

Leica Microsystems launches the Leica DFC9000, a monochrome microscope camera with a highly sensitive third-generation sCMOS sensor. The camera enables researchers to image live cells under near-native conditions, allowing them to gain a better understanding of cellular processes and dynamics.

From Leica Microsystems GmbH 12 Apr 2016

Researchers develop new technology to tailor grafted tissues

Researchers from the Technion-Israel Institute of Technology and colleagues in the U.S. have developed technology to tailor grafted tissues that can respond to certain natural forces affecting blood vessels.

12 Apr 2016

Brazilian researchers reveal harmful effects of Zika virus in human neural stem cells, neurospheres

Brazilian researchers from the D'Or Institute for Research and Education (IDOR) and Federal University of Rio de Janeiro (UFRJ) have demonstrated the harmful effects of ZIKA virus (ZIKV) in human neural stem cells, neurospheres and brain organoids.

12 Apr 2016

Certain red blood cell manufacturing methods may be less damaging to cells than others

Scientists from Blood Systems Research Institute in San Francisco, California, and Canadian Blood Services' Centre for Innovation lab in Edmonton, Alberta, report for the first time that specific red blood cell manufacturing methods may be less damaging to cells than others.

12 Apr 2016

Combination of genetic, environmental risk factors can trigger fatal eating disorder in humans

In a new study, researchers from Columbia University Medical Center described a new mouse model featuring a combination of genetic and environmental risk factors that can trigger the compulsive restriction of food intake seen in patients with anorexia nervosa. The findings may help to identify new prevention and treatment strategies for the eating disorder in humans.

12 Apr 2016

Glial cells can modulate specific nerve endings in the brain, find Rockefeller scientists

More than half of our brains are made up of glial cells, which wrap around nerve fibers and insulate them--similarly to how the plastic casing of an electric cable insulates the copper wire within--allowing electrical and chemical impulses to travel faster.

12 Apr 2016

Pooled analysis from seven clinical studies demonstrates consistent efficacy for ceftazidime-avibactam in the treatment of multi-drug resistant gram-negative bacteria

AstraZeneca has presented positive data demonstrating the efficacy of the investigational antibiotic, ceftazidime-avibactam (CAZ-AVI), in treating patients with ceftazidime-resistant Gram-negative infections, which are increasingly resistant to most available antibiotics, often precipitating the need for clinicians to reach for agents previously reserved for last-line use.

12 Apr 2016

Research suggests new pathway for preventing optic nerve damage in KPro recipients

Researchers from Massachusetts Eye and Ear/Harvard Medical School have identified inflammatory factors that cause optic neuropathy in the back of the eye following implantation of a keratoprosthesis (KPro) — similar to what glaucoma patients experience, without the rise of pressure in the eye — and have shown that blocking one of those factors, tumor necrosis factor alpha (TNFa), successfully halts the development of optic nerve damage in a mouse model.

11 Apr 2016

Research shows viruses work in groups to attack host cells more effectively

Research at the Cavanilles Institute of Biodiversity and Evolutionary Biology of the University of Valencia, led by professor Rafael Sanjuán, reveals that viruses work in groups to attack host cells more effectively. The results of this study were published in the journal 'Cell Host & Microbe'.

11 Apr 2016

Mouse-based study shows exercise decreases cancer incidence, slows tumor growth

When you're pounding along an icy pavement or sweating through a gym workout, you try to remind yourself of the many health benefits of exercise. Between gasps, you can say that a healthy, fit lifestyle helps prevents obesity, a worldwide problem of increasing magnitude that has been linked to cardiovascular disease and diabetes.

11 Apr 2016

Flexible ramp scripting interface added for BioScope Resolve BioAFM

At the 7th AFM BioMed Conference, Bruker’s Nano Surfaces Division today announced the release of RampScript™, which provides extensive new scripting capabilities for the BioScope Resolve® BioAFM. BioScope Resolve has set new standards for highest resolution AFM imaging with the first ever images of microvilli on live cells and by routinely resolving submolecular structures, such as the major and minor groove of DNA, while operating on an inverted microscope.

From Bruker Nano Surfaces and Metrology 11 Apr 2016

Researchers identify vital inflammatory mechanisms in type 1 diabetes, obesity-related kidney dysfunction

In a new study, published in the online edition of the journal EBioMedicine, a multi-disciplinary team led by researchers at University of California, San Diego School of Medicine has identified key inflammatory mechanisms underlying type 1 diabetes and obesity-related kidney dysfunction.

11 Apr 2016

Researchers find evidence that protein involved in regulating inflammation has anti-septic effects

Sepsis represents a serious complication of infection and is one of the leading causes of death and critical illness worldwide due in part to the lack of effective therapies. A report in the American Journal of Pathology provides evidence from both mouse and human studies that SHARPIN, a protein involved in regulating inflammation, has anti-septic effects. These findings may spur development of novel sepsis treatments.

11 Apr 2016

T Cell News and Research

Latest T Cell News and Research

Bacteroidia pilins prevalent in human gut and mouth form new type of pili to cling to hosts

Six newly identified proteins may help potentially unlock new insights into aging-related diseases

Distribution of c-Myc protein during asymmetric cell division influences fate, roles of activated T cells

Cell-signaling protein holds key to understanding autoantibody formation in lupus patients

Alternative splicing regulates MALT1 protein to have stronger or weaker effect on immune system

Abnormally active Rab5 protein leads to early development of neurodegenerative disease

Researchers investigate biochemical, physiological characteristics of facial and extraocular muscles

Leica Microsystems launches new camera for imaging live cells under near-native conditions

Researchers develop new technology to tailor grafted tissues

Brazilian researchers reveal harmful effects of Zika virus in human neural stem cells, neurospheres

Certain red blood cell manufacturing methods may be less damaging to cells than others

Combination of genetic, environmental risk factors can trigger fatal eating disorder in humans

Glial cells can modulate specific nerve endings in the brain, find Rockefeller scientists

Pooled analysis from seven clinical studies demonstrates consistent efficacy for ceftazidime-avibactam in the treatment of multi-drug resistant gram-negative bacteria

Research suggests new pathway for preventing optic nerve damage in KPro recipients

Research shows viruses work in groups to attack host cells more effectively

Mouse-based study shows exercise decreases cancer incidence, slows tumor growth

Flexible ramp scripting interface added for BioScope Resolve BioAFM

Researchers identify vital inflammatory mechanisms in type 1 diabetes, obesity-related kidney dysfunction

Researchers find evidence that protein involved in regulating inflammation has anti-septic effects

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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