T Cell News and Research

Latest T Cell News and Research

Scientists develop innovative technique to deliver cancer drugs deep into tumour cells

Scientists at Nanyang Technological University (NTU Singapore) have invented a new way to deliver cancer drugs deep into tumour cells.

18 Apr 2016

African sleeping sickness parasite has defence mechanism against potential pharmaceuticals

Researchers from Umea University in Sweden have discovered that the single-celled parasite causing African sleeping sickness has a defence mechanism against potential pharmaceuticals under development against the disease. The deadly parasite has an enzyme that can cleave and hence disarm adenosine analogue pharmaceuticals. This according to a study recently published in the Journal of Biological Chemistry.

18 Apr 2016

Study shows safety of experimental drug guadecitabine in colorectal cancer patients

In a small, phase I clinical trial, Johns Hopkins Kimmel Cancer Center researchers say they show for the first time that the experimental drug guadecitabine (SGI-110) is safe in combination with the chemotherapy drug irinotecan and may overcome resistance to irinotecan in patients with metastatic colorectal cancer.

18 Apr 2016

Survivin inhibitor with chemotherapy provides therapeutic advantage for Rb cells, tumors

Researchers at The Saban Research Institute of Children's Hospital Los Angeles (CHLA) have demonstrated that targeting survivin - a protein that inhibits apoptosis or cell death - enhances the effectiveness of chemotherapy in cells and mouse models of retinoblastoma (Rb), the most common malignant tumor of the eye in children.

18 Apr 2016

Scientists identify unique memory suppressor gene that could provide clues for new Alzheimer’s disease treatments

While research has identified hundreds of genes required for normal memory formation, genes that suppress memory are of special interest because they offer insights into how the brain prioritizes and manages all of the information, including memories, that it takes in every day.

18 Apr 2016

Cholesterol-fighting drug molecule can kill prostate cancer cells

Standard treatment for prostate cancer can include chemotherapy that targets receptors on cancer cells. However, drug-resistant cancer cells can emerge during chemotherapy, limiting its effectiveness as a cancer-fighting agent. Researchers at the University of Missouri have proven that a compound initially developed as a cholesterol-fighting molecule not only halts the progression of prostate cancer, but also can kill cancerous cells.

16 Apr 2016

Scientists find way to control behaviour of cardiomyocytes using laser radiation

Scientists from MIPT's Laboratory of the Biophysics of Excitable Systems have discovered how to control the behaviour of heart muscle cells (cardiomyocytes) using laser radiation; this study will help scientists to better understand the mechanisms of the heart and could ultimately provide a method of treating arrhythmia. The paper has been published in the journal PLOS ONE.

16 Apr 2016

Scientists identify human protein that weakens immune response to HIV, other viruses

Scientists at the University of North Carolina School of Medicine and Sanford Burnham Prebys Medical Discovery Institute have identified a human (host) protein that weakens the immune response to HIV and other viruses. The findings, published today in Cell Host & Microbe, have important implications for improving HIV antiviral therapies, creating effective viral vaccines, and advance a new approach to treat cancer.

16 Apr 2016

Mouse model offers insight into molecular, neurological basis of stuttering

Mice that vocalize in a repetitive, halting pattern similar to human stuttering may provide insight into a condition that has perplexed scientists for centuries, according to a new study by researchers at Washington University School of Medicine in St. Louis and the National Institutes of Health.

16 Apr 2016

Genetic modification of common virus gives extra weapon to kill cancer cells

A common flu virus could be used to overcome patients' resistance to certain cancer drugs -- and improve how those drugs kill cancer cells, according to new research from Queen Mary University of London.

16 Apr 2016

Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

The removal of the enzyme Dnmt1 during oligodendrocyte progenitor cell (OPC) differentiation in the central nervous system resulted in inefficient myelin formation and neurological deterioration, including loss of control of bodily movements, in mice, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published today in the medical journal Cell Reports. The results could lead to a new understanding of multiple sclerosis and other myelin disorders in humans.

16 Apr 2016

FOXO proteins affect dozens of genes common to worms, flies, mice and humans

Whether a creature is a worm, a fly, a mouse, or a human, death inevitably awaits. And not only do these organisms share a common fate, but also, according to a new study, they may share some of the specific mechanisms of mortality. The researchers found that in all four species, there are 46 genes regulated by the same family of "FOXO" proteins known to be central in aging and longevity.

16 Apr 2016

Slow-wave sleep may promote consolidation of recent memories

Research strongly suggests that sleep, which constitutes about a third of our lives, is crucial for learning and forming long-term memories. But exactly how such memory is formed is not well understood and remains, despite considerable research, a central question of inquiry in neuroscience.

16 Apr 2016

Inflammation after stroke may help the brain to self-repair

After a stroke, there is inflammation in the damaged part of the brain. Until now, the inflammation has been seen as a negative consequence that needs to be abolished as soon as possible. But, as it turns out, there are also some positive sides to the inflammation, and it can actually help the brain to self-repair.

16 Apr 2016

Scientists find new way to defend against deadly malarial parasite

The most dangerous malaria parasite, Plasmodium falciparum, is responsible for nearly half a million deaths annually across Africa and Southeast Asia. Of increasing concern, this parasite is now developing resistance to common antimalarial drugs.

15 Apr 2016

Improving body clock could protect against metabolic syndrome

Essential biological processes are managed by an internal timer or body clock. When the body clock gets out of whack, conditions such as metabolic syndrome can occur.

15 Apr 2016

Low cost technique could fabricate microfluidic devices for biomedical applications

In this work, Dr. Diana and fellow researchers propose a low cost technique able to produce microfluidic devices for biomedical applications. The most common technique to fabricate biomedical microdevices is soft-lithography. However, it is a costly and time-consuming technique. Progress in manufacturing milling tools smaller than 100 µm, has enabled the use of micromilling machines to fabricate microfluidic devices capable of performing cell separation.

15 Apr 2016

Taking antibiotics in early childhood can disrupt immune system function lifelong

Scientists want to know whether taking antibiotics early in life can disrupt your immune system function lifelong.

15 Apr 2016

New research in SIV-exposed monkeys provides insights for development of HIV prevention strategies

New research in monkeys exposed to SIV, the monkey equivalent of HIV, suggests that the virus spreads rapidly in the body and triggers early host responses that suppress antiviral immunity, thus promoting viral replication.

15 Apr 2016

Newly found mechanism of color vision illustrates why people perceive color blue in dim light

The swirling skies of Vincent Van Gogh's Starry Night illustrate a mystery that has eluded biologists for more than a century--why do we perceive the color blue in the dimly lit night sky? A newly discovered mechanism of color vision in mice might help answer this question, Caltech researchers say.

15 Apr 2016

T Cell News and Research

Latest T Cell News and Research

Scientists develop innovative technique to deliver cancer drugs deep into tumour cells

African sleeping sickness parasite has defence mechanism against potential pharmaceuticals

Study shows safety of experimental drug guadecitabine in colorectal cancer patients

Survivin inhibitor with chemotherapy provides therapeutic advantage for Rb cells, tumors

Scientists identify unique memory suppressor gene that could provide clues for new Alzheimer’s disease treatments

Cholesterol-fighting drug molecule can kill prostate cancer cells

Scientists find way to control behaviour of cardiomyocytes using laser radiation

Scientists identify human protein that weakens immune response to HIV, other viruses

Mouse model offers insight into molecular, neurological basis of stuttering

Genetic modification of common virus gives extra weapon to kill cancer cells

Removal of Dnmt1 enzyme during OPC differentiation could lead to neurological symptoms

FOXO proteins affect dozens of genes common to worms, flies, mice and humans

Slow-wave sleep may promote consolidation of recent memories

Inflammation after stroke may help the brain to self-repair

Scientists find new way to defend against deadly malarial parasite

Improving body clock could protect against metabolic syndrome

Low cost technique could fabricate microfluidic devices for biomedical applications

Taking antibiotics in early childhood can disrupt immune system function lifelong

New research in SIV-exposed monkeys provides insights for development of HIV prevention strategies

Newly found mechanism of color vision illustrates why people perceive color blue in dim light

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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