T Cell News and Research

Latest T Cell News and Research

Study reveals new insights into the effects of chemotherapy on tumor microenvironment

Research from Queen Mary University of London has revealed novel insights into the effects of chemotherapy on the tumor microenvironment (TME).

12 Apr 2021

Aneuploidy testing can be key in determining optimal treatment for lung cancer patients

Patients with non-small cell lung cancer (NSCLC) whose cancer cells have low levels of aneuploidy - an abnormal number of chromosomes - tend to respond better to immune checkpoint inhibitor drugs than patients with higher levels, Dana-Farber Cancer Institute researchers will report at the virtual AACR Annual Meeting 2021.

12 Apr 2021

Study shows how nitrate controls gene expression in legumes

Plants in the bean family (legumes) form nodules on their roots to take up nitrogen. Legumes will stop nodule production when nitrogen is plentiful, but precisely how nitrate presence controls nodule formation in these plants has been a mystery.

12 Apr 2021

Researchers unveil new SARS-CoV-2 inhibitor that targets viral immune evasion

In a recent quest for an effective antiviral compound, UK researchers have purified a specific enzyme of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) known as nsp15 and optimized fluorescent biochemical endoribonuclease assays to screen a custom chemical library with over 5,000 commercial compounds. The study is currently available on the bioRxiv* preprint server.

11 Apr 2021

Previously approved drugs starting points for COVID-19 therapeutics

Researchers in the United States have identified several clinically approved compounds that could be repurposed for the treatment and prevention of coronavirus disease 2019 (COVID-19).

11 Apr 2021

New polypeptide could provide universal protection against coronaviruses

Researchers in the United States have developed an inhibitor of the spike protein found on the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that limits its formation in host human cells that would otherwise be the source of newly generated virions.

11 Apr 2021

New consortium aims to accelerate development of stem cell-based therapies for Huntington’s disease

The Stem Cells for Huntington's Disease (SC4HD) is a new international consortium created to promote advanced therapy medicinal product (ATMP) through cell transplantation studies on Huntington's Disease.

9 Apr 2021

Obesity reduces mitochondrial gene expression in fat tissue, finds study

A twin study recently completed at the University of Helsinki indicates that the machinery responsible for energy handling in fat tissue is working poorly in obesity.

9 Apr 2021

Study uncovers molecular reason why fecal transplants effectively treat C. difficile infections

Experts have uncovered a new molecular reason why faecal transplants are highly effective in treating infections such as C. difficile (a nasty bacteria that can infect the bowel), which could lead to more targeted treatments for this and other similar diseases.

9 Apr 2021

Researchers use genetics to identify potential drugs for early management of COVID-19

A new study using human genetics suggests researchers should prioritize clinical trials of drugs that target two proteins to manage COVID-19 in its early stages.

9 Apr 2021

Advanced computer model could lead to improvements in 'bionic eye' technology

There are millions of people who face the loss of their eyesight from degenerative eye diseases. The genetic disorder retinitis pigmentosa alone affects 1 in 4,000 people worldwide.

9 Apr 2021

Children may be less infectious in spreading SARS-CoV-2 to others

Children may not be as infectious in spreading SARS-CoV-2 to others as previously thought, according to new University of Manitoba-led research in CMAJ.

9 Apr 2021

Brain organoid models reveal mechanisms linked to virus-induced microcephaly

Researchers at IMBA - Institute of Molecular Biotechnology of the Austrian Academy of Sciences - demonstrate that different viruses can lead to brain malformations through diverse mechanisms by using human brain organoid models.

9 Apr 2021

Study shows intricate association of aluminum in the neuropathology of familial Alzheimer's disease

This study builds upon two earlier published studies (Mold et al., 2020, Journal of Alzheimer's Disease Reports) from the same group. The new data, also published in the Journal of Alzheimer's Disease Reports, demonstrate that aluminum is co-located with phosphorylated tau protein, present as tangles within neurons in the brains of early-onset or familial Alzheimer's disease (AD).

9 Apr 2021

Scientists compare DNA damaging properties of chemicals from vape products and cigarettes

Imperial Brands scientists have utilized Toxys' ToxTracker suite of stem-cell based in-vitro assays, which provide mechanistic insight into the potential DNA damaging properties of chemicals, comparing vape e-liquid samples and their aerosols to combustible cigarette smoke.

9 Apr 2021