T Cell News and Research

Latest T Cell News and Research

Otago researchers find how to treat heart disease in type-2 diabetics

University of Otago researchers have discovered one of the reasons why more than 50 per cent of people with type 2 diabetes die from heart disease.

12 Mar 2021

Study identifies three novel binding receptors for SARS-CoV-2

A team of scientists from the United Kingdom recently conducted a large-scale screening of several membrane-bound and soluble host cell receptors to identify novel binding partners for SARS-CoV-2. They have identified three novel receptors expressed on the human cell membrane; of which, one binds to SARS-CoV-2 spike with similar affinity as angiotensin-converting enzyme 2 (ACE2).

12 Mar 2021

Natural virus-induced immunity protective against UK and South African SARS-CoV-2 variants in hamster study

As new variants of SARS-CoV-2 continue to emerge, fueling the continued spread of the COVID-19 pandemic, a new study offers encouragement.

12 Mar 2021

Impact of type I interferon (IFN) autoantibodies in critical COVID-19

A new preprint discusses the pathogenesis of this critical COVID-19 with reference to autoimmune phenomena involving the key antiviral type I interferon pathway.

12 Mar 2021

Optimizing The Genome Editing Workflow With Microfluidic Technology

A recent grant collaboration, funded by Innovate UK, between Sphere Fluidics, University of Edinburgh, Horizon Discovery, OXGENE, and Twist Bioscience has culminated in a prototype automated microfluidic genome editing platform.

From Sphere Bio 12 Mar 2021

Novel tool can add or remove sugar from proteins

Sugar has been called "evil," "toxic," and "poison." But the body needs sugars, too. Sugar molecules help cells recognize and fight viruses and bacteria, shuttle proteins from cell to cell, and make sure those proteins function.

12 Mar 2021

Immune-modified ex vivo platform can measure treatment response of ovarian cancer

KIYATEC, Inc researchers demonstrated that their immune-modified ex vivo platform can measure treatment response through direct interaction between a patient's cancer and infiltrating immune cells, and immuno-oncology agents.

12 Mar 2021

Study shows how functional biomaterials rely on interfacial protein layer to transmit signals to living cells

An interdisciplinary research team at Lehigh University has unraveled how functional biomaterials rely upon an interfacial protein layer to transmit signals to living cells concerning their adhesion, proliferation and overall development

12 Mar 2021

New study sheds light on cancer metastasis

Breast cancer is harmful enough on its own, but when cancer cells start to metastasize -- or spread into the body from their original location -- the disease becomes even more fatal and difficult to treat.

12 Mar 2021

Scientists increase potency of HIV-1 antibody, identify new ways to develop vaccines

Much like coronavirus, circulating HIV-1 viruses mutate into diverse variants that pose challenges for scientists developing vaccines to protect people from HIV/AIDS.

12 Mar 2021

Spike protein mutations in SARS-CoV-2 variants help resist antibody neutralization

Researchers based in Beijing and Shenzhen, China, report that they have identified mutations in the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that may allow variant strains to avoid neutralization by monoclonal antibodies and convalescent blood plasma.

11 Mar 2021

Structure and function of locked conformation of the SARS-CoV-2 spike protein identified

A new preprint research paper, posted to the bioRxiv* server, uncovered more information on the different structural conformations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The findings suggest the spike protein turns into a locked state to stabilize the spike protein during virus egress.

11 Mar 2021

Study addresses glycosylation concerns in SARS-CoV-2 vaccine design

An international team of researchers has found that glycosylation patterns are conserved across the native spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – and the recombinant spike proteins made in laboratories for use in vaccines.

11 Mar 2021

Newly discovered cellular stress enzyme may be a target for neurodegenerative disease treatments

An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health.

11 Mar 2021

Princeton researchers elucidate how hepatitis B virus establishes chronic infection

Researchers at Princeton have determined how five cellular proteins contribute to an essential step in the life cycle of hepatitis B virus (HBV).

11 Mar 2021

Studies reveal how kidney tumors' microenvironments change in response to immunotherapy

In the last two decades, immunotherapy has emerged as a leading treatment for advanced renal carcinoma cancer (more commonly known as kidney cancer).

11 Mar 2021

Study reveals how lung alveolus forms at cellular level

Researchers from Children's Hospital of Philadelphia have determined what happens at a cellular level as the lung alveolus forms and allows newborns to breathe air.

11 Mar 2021

Lithium chloride can alleviate radiation-induced oral mucositis and taste dysfunction

Oral mucositis and taste dysfunction (dysgeusia) occurs in nearly all patients receiving head and neck radiotherapy and tremendously affects the quality of life and treatment outcome.

11 Mar 2021

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore have developed a CRISPR-based gene editor, C-to-G Base Editor (CGBE), to correct mutations that cause genetic disorders.

11 Mar 2021

SARS-CoV-2 can infect blood monocytes and trigger inflammation, finds study

Researchers found about 10% of blood monocytes in coronavirus disease 2019 (COVID-19) patients are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). These monocytes then die, leading to the release of cytokines – a feature associated with severe and critical COVID-19.

11 Mar 2021

T Cell News and Research

Latest T Cell News and Research

Otago researchers find how to treat heart disease in type-2 diabetics

Study identifies three novel binding receptors for SARS-CoV-2

Natural virus-induced immunity protective against UK and South African SARS-CoV-2 variants in hamster study

Impact of type I interferon (IFN) autoantibodies in critical COVID-19

Optimizing The Genome Editing Workflow With Microfluidic Technology

Novel tool can add or remove sugar from proteins

Immune-modified ex vivo platform can measure treatment response of ovarian cancer

Study shows how functional biomaterials rely on interfacial protein layer to transmit signals to living cells

New study sheds light on cancer metastasis

Scientists increase potency of HIV-1 antibody, identify new ways to develop vaccines

Spike protein mutations in SARS-CoV-2 variants help resist antibody neutralization

Structure and function of locked conformation of the SARS-CoV-2 spike protein identified

Study addresses glycosylation concerns in SARS-CoV-2 vaccine design

Newly discovered cellular stress enzyme may be a target for neurodegenerative disease treatments

Princeton researchers elucidate how hepatitis B virus establishes chronic infection

Studies reveal how kidney tumors' microenvironments change in response to immunotherapy

Study reveals how lung alveolus forms at cellular level

Lithium chloride can alleviate radiation-induced oral mucositis and taste dysfunction

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

SARS-CoV-2 can infect blood monocytes and trigger inflammation, finds study

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Reducing polypharmacy through innovative drug formulation technologies

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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