T Cell News and Research

Latest T Cell News and Research

Researchers are developing a new class of compounds against various cancers

Researchers at The Wistar Institute and collaborators from the University of Notre Dame are developing anticancer compounds targeting a pathway of the endoplasmic reticulum (ER) stress response implicated in the development of multiple myeloma (MM), chronic lymphocytic leukemia (CLL) and lymphoma.

14 Oct 2020

Physically squeezing cells can trigger cells to grow and divide faster

The closer people are physically to one another, the higher the chance for exchange, of things like ideas, information, and even infection.

14 Oct 2020

D614G mutation in SARS-CoV-2 increases viral fitness and infectivity

Researchers from the Duke Human Vaccine Institute and Duke University, Durham NC, USA, recently analyzed the D614G mutation in SARS-CoV-2 in the context of a soluble S ectodomain construct. Their study has been published in the preprint server bioRxiv.

14 Oct 2020

Children and teens can spread SARS-CoV-2 in their households

A team of researchers from the Georgia Department of Public Health and the U.S Centers for Disease Control and Prevention (CDC) aimed to determine the secondary attack rates (SAR) among household contacts of children and adolescents who contracted SARS-CoV-2 during an outbreak at an overnight camp in June.

13 Oct 2020

Pre-existing immunity to other coronaviruses may be poor

Brenda M. Westerhuis et al., in a recent medRxiv* preprint paper, investigate the antibody cross-reactivity - to explain the severe disease. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

13 Oct 2020

Microstructural brain differences linked to waist circumference and BMI in children

Differences in the microstructure of the nucleus accumbens (NAcc), a region in the brain that plays an important role in processing food and other reward stimuli, predict increases in indicators of obesity in children, according to a study funded by the National Institute on Drug Abuse and nine other institutes, all part of the National Institutes of Health.

13 Oct 2020

Cancer-killing T cells release chemicals to direct swarms towards tumors

When immune system T cells find and recognise a target, they release chemicals to attract more T cells which then swarm to help subdue the threat, shows a new study published today in eLife.

13 Oct 2020

Scientists combine a chemotherapeutic and photodynamic approach to fight cancer

In their quest to destroy cancer cells, researchers are turning to combinational therapies more and more. Scientists from Germany and China have now combined a chemotherapeutic and photodynamic approach.

13 Oct 2020

Bacterial toxin stimulates tissue regeneration

Normally they are among the many harmless organisms found in and on the human body: one in four people have millions of Staphylococcus aureus bacteria on their skin and on the mucous membranes of the upper respiratory tract, without being aware of it.

13 Oct 2020

Drug derived from a natural human protein could stop lethal lung damage from the flu

The raging lung inflammation that can contribute to death from the flu can be stopped in its tracks by a drug derived from a naturally occurring human protein, a new animal study suggests.

13 Oct 2020

Are antibiotics being over prescribed in COVID-19?

A new study published on the preprint server medRxiv in October 2020 shows that the baseline levels of inflammatory markers and C-reactive protein (CRP) in relation to antibiotic administration can rule out bacterial co-infections and help reduce the unnecessary use of antibiotics.

13 Oct 2020

PPE may account for low SARS-CoV-2 seroprevalence in healthcare workers

A recent study published on the preprint server medRxiv in October 2020 shows that among healthcare workers, and especially among first responders, less than 1% and just over 5%, respectively, had antibodies to the virus.

13 Oct 2020

Novel findings on mole growth could pave way for skin cancer treatments

Moles stop growing when they reach a certain size due to normal interactions between cells, despite having cancer-associated gene mutations, says a new study published today in eLife.

13 Oct 2020

New computational approach improves characterization of cellular diversity

Researchers in the United States have developed a computational method called “weighted-nearest neighbor” (WNN) analysis that can significantly improve the ability to define cellular states across various biological contexts and data types.

13 Oct 2020

CAR NKT cells offer a promising approach to combat hard-to-treat solid tumors

Natural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have been developed into a novel form of immunotherapy to treat patients with cancer.

13 Oct 2020

How SARS-CoV-2's spike protein highjacks the host cell trafficking machinery

Researchers at The Medical Research Council Laboratory of Molecular Biology have conducted a study showing how the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein interacts with host cell factors in ways that promote the formation of syncytia.

13 Oct 2020