T Cell News and Research

Latest T Cell News and Research

Blocking nuclear pore complex formation can help selectively kill cancer cells

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that blocking the construction of nuclear pores complexes--large channels that control the flow of materials in and out of the cell nucleus--shrank aggressive tumors in mice while leaving healthy cells unharmed.

28 Sep 2020

Epigenetic changes in the brain drive late-onset Alzheimer's disease

New findings suggest that late-onset Alzheimer's Disease is driven by epigenetic changes -- how and when certain genes are turned on and off -- in the brain. Results were published today in Nature Genetics.

28 Sep 2020

Scientists identify a new way to regulate cell plasticity

Cell plasticity is a property by which a cell can take on different and reversible identities. Cell plasticity is also essential for embryo development and for the correct function of the immune system.

28 Sep 2020

New mechanism that prevents hair loss identified

A team of researchers from Cologne and Helsinki has discovered a mechanism that prevents hair loss: hair follicle stem cells, essential for hair to regrow, can prolong their life by switching their metabolic state in response to low oxygen concentration in the tissue.

28 Sep 2020

Researchers decipher how the immune system memorizes pathogens after an infection

The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. Now, scientists at the University of Würzburg have deciphered new details of this process.

28 Sep 2020

Targeted therapy found to be effective at shrinking tumors in patients with nonsmall-cell lung cancer

An international team of researchers has found that selpercatinib, a drug that precisely targets cancers driven by mutations or alterations in the gene RET, was effective at shrinking tumours in patients with nonsmall cell lung cancer (NSCLC), with a majority of patients living for more than a year without disease progression.

28 Sep 2020

NCCN publishes new clinical practice guidelines for pediatric Hodgkin lymphoma

The National Comprehensive Cancer Network today announced the publication of new NCCN Clinical Practice Guidelines in Oncology for Pediatric Hodgkin Lymphoma. Hodgkin lymphoma is one of the most curable forms of pediatric cancer, with long-term survival rates of 90% or higher.

28 Sep 2020

New framework allows researchers to probe the metabolic processes inside cancer cells

One of the biggest challenges to the development of medical treatments for cancer is the fact that there is no single kind of cancer.

28 Sep 2020

Multifunctional cell therapy system raises hopes to treat inflammatory bowel disease

The research by the UPV/EHU-University of the Basque Country, in collaboration with Harvard University, has yielded highly encouraging results, and studies in animal models have already begun

28 Sep 2020

BAT study analyzes the toxicological impact of nicotine pouch products

New research by BAT indicates that modern oral products (MOPs) showed lower toxicity responses in certain assays than traditional cigarettes.

28 Sep 2020

Genetic mutations hinder immune response in severe COVID-19

Now, a truly international team of nearly 140 researchers aimed to determine why some people develop severe illness when once infected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19 disease.

28 Sep 2020

Clover Biopharma's new trimeric subunit vaccine candidate prevents COVID-19 in monkeys

The vaccine candidate produced a high level of neutralizing antibodies in animal models. Rhesus macaques immunized with the vaccine candidate showed reduced viral loads in the lungs. The research is published on the preprint server bioRxiv.

28 Sep 2020

Special formulation of inhaled niclosamide may be effective against SARS-CoV-2

Now in new research published on the preprint server bioRxix*, a novel formulation of the drug Niclosamide (NIC) is observed to be effective against SARS-CoV-2 and MERS-CoV in mouse models; it also protects against methicillin-resistance Staphylococcus aureus pneumonia and inflammatory lung damage.

28 Sep 2020

Anti-N-protein IgG may predict severity of COVID-19

A recent study by researchers at the University of Miami, Miami VA Healthcare System and Express Gene and published on the preprint server medRxiv in September 2020 reports on the prognostic significance of the anti-N Immunoglobulin G (IgG) antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Sep 2020

Risk factors for mortality among hospitalized patients with COVID-19

A new study by scientists at biotechnology company Genentech, Inc., and published on the preprint server medRxiv in September 2020 attempts to identify the factors which may shape the risk for death in COVID-19 disease.

27 Sep 2020

CRISPR screening identifies human host pathways that facilitate coronavirus infection

The human coronavirus family consists of 7 known pathogens, for which there are no approved vaccines or specific therapeutic options. Although the seasonal human coronaviruses - OC43, HKU1, 229E, and NL63 – only cause mild respiratory infections, three highly pathogenic coronaviruses that emerged in the last two decades revealed the pandemic potential of this family of viruses.

27 Sep 2020

Human recombinant soluble ACE2 successfully used in a patient with severe COVID-19

A multinational research group recently published a paper in the journal Lancet Respiratory Medicine which describes the first patient with a severe form of coronavirus disease (COVID-19) that was successfully treated with human recombinant soluble ACE2.

27 Sep 2020

Complex SARS-CoV-2 serology means universal immunological assay is not feasible

As we improve our understanding of immune responses and correlates of protection against the severe acute respiratory syndrome coronavirus (SARS-CoV-2), two UK researchers emphasize that we will probably utilize different assays to tackle specific questions. Their commentary is published in the prestigious journal Lancet Infectious Diseases.

27 Sep 2020

How many "listeners" a nerve cell has is strictly regulated, shows study

How many "listeners" a nerve cell has in the brain is strictly regulated. This is shown by an international study led by the University College London and the universities of Bonn, Bordeaux and Milton Keynes (England).

26 Sep 2020

Marine bacteria optimize nutrient uptake by switching between dispersal and resource exploitation

To stay, or not to stay? When it comes to nutrient resource patches, researchers from Japan and Switzerland have discovered that marine bacteria have a knack for exploiting them efficiently, timing movements between patches to get the best resources.

26 Sep 2020

T Cell News and Research

Latest T Cell News and Research

Blocking nuclear pore complex formation can help selectively kill cancer cells

Epigenetic changes in the brain drive late-onset Alzheimer's disease

Scientists identify a new way to regulate cell plasticity

New mechanism that prevents hair loss identified

Researchers decipher how the immune system memorizes pathogens after an infection

Targeted therapy found to be effective at shrinking tumors in patients with nonsmall-cell lung cancer

NCCN publishes new clinical practice guidelines for pediatric Hodgkin lymphoma

New framework allows researchers to probe the metabolic processes inside cancer cells

Multifunctional cell therapy system raises hopes to treat inflammatory bowel disease

BAT study analyzes the toxicological impact of nicotine pouch products

Genetic mutations hinder immune response in severe COVID-19

Clover Biopharma's new trimeric subunit vaccine candidate prevents COVID-19 in monkeys

Special formulation of inhaled niclosamide may be effective against SARS-CoV-2

Anti-N-protein IgG may predict severity of COVID-19

Risk factors for mortality among hospitalized patients with COVID-19

CRISPR screening identifies human host pathways that facilitate coronavirus infection

Human recombinant soluble ACE2 successfully used in a patient with severe COVID-19

Complex SARS-CoV-2 serology means universal immunological assay is not feasible

How many "listeners" a nerve cell has is strictly regulated, shows study

Marine bacteria optimize nutrient uptake by switching between dispersal and resource exploitation

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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