T Cell News and Research

Latest T Cell News and Research

'Microbial dark matter' can affect cholesterol levels in humans

In the darkest parts of the world where light fails to block out the unfathomable bounty of the stars, look up. There are still fewer specks illuminating the universe than there are bacteria in the world, hidden from sight, a whole universe inside just one human gut.

17 Jun 2020

NTU researchers develop a sustainable way to extract high-quality antimicrobial compounds

Scientists from Nanyang Technological University, Singapore have developed a sustainable and green way to extract high-quality antimicrobial compounds from seeds.

17 Jun 2020

Nanosponges could attack and neutralize SARS-COV-2 virus

Nanoparticles cloaked in human lung cell membranes and human immune cell membranes can attract and neutralize the SARS-CoV-2 virus in cell culture, causing the virus to lose its ability to hijack host cells and reproduce.

17 Jun 2020

An improved tetravalent antibody blocks SARS-CoV-2 infection

A new study published on the preprint server bioRxiv* in June 2020 shows the potential of a new fusion molecule called a biparatopic protein to inhibit viral interaction with the host cell ACE2 receptor. This could lead to therapeutic applications.

17 Jun 2020

Researchers investigate how neural circuits enable the brain to regulate basal sighing

One group of neurons controls various types of sighing, but they receive their instructions from different areas of the brain depending on the reason for the sigh, according to a study scheduled to publish June 16 in the journal Cell Reports.

17 Jun 2020

BioRescue consortium is developing new technologies to prevent the extinction of species

In order to prevent the extinction of species such as the northern white rhino, the BioRescue consortium is developing new methods and technologies for conservation.

17 Jun 2020

Mapping RNA sequences of therapeutic value in the SARS-CoV-2 genome

Now, in new research published on the preprint server bioRxiv European scientists have performed RNA structure probing to obtain a single-base resolution secondary structure map of the full SARS-CoV-2 coronavirus genome.

17 Jun 2020

SARS-CoV-2 mutated spike proteins show variations in cell entry

A new study by Japanese scientists published on the preprint server bioRxiv* in June 2020 shows that the D614g mutation in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein can enhance the infectivity of the virus while leaving it vulnerable to neutralization by antibodies.

17 Jun 2020

Novel ACE2-antibody fusion molecules show anti-SARS-CoV-2 activity

Now, in a new study published on the preprint server, bioRxiv researchers in the U.S. investigated a soluble version of ACE2 for SARS-CoV-2 viral neutralization activity.

17 Jun 2020

Scientists isolate powerful SARS-CoV-2 -neutralizing antibodies from COVID-19 patients

A new study has shown that potent antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could help protect against COVID-19 infection. Preliminary results in animal studies have so far proven successful. The study titled, "Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model," was published in the latest issue of the journal Science.

17 Jun 2020

Antibiotic X-206 effective against SARS-CoV-2 in vitro

The current study published on the preprint server bioRxiv aims to understand how these compounds affect SARS-CoV-2 in vitro. The researchers from Aarhus University in Denmark examined 11 natural PEIs, with a single synthetic analog, screening them for inhibitory activity against the CPE of SARS-CoV-2 infecting cultured cells with overexpression of TMPRSS2, a serine protease that is instrumental in cleaving the spike protein of the virus.

16 Jun 2020

How antibodies neutralize SARS-CoV-2 in convalescent patients

A new study by researchers from the United Kingdom and Taiwan and published on the preprint server bioRxiv in June 2020 describes the structural basis for the neutralizing effect of the SARS-CoV-2 antibody on the virus. This also indicates a possible therapeutic molecule by identifying its binding epitope as possibly a major neutralizing site.

16 Jun 2020

Anti-TNF drug preserves beta-cell function in newly diagnosed pediatric patients with Type 1 diabetes

In research led by a University at Buffalo pediatric endocrinologist, a drug called golimumab showed that it preserved beta-cell function in children and young adults with newly diagnosed Type 1 diabetes, according to findings from a Phase 2 study.

16 Jun 2020

Researchers create superior bone grafts using primitive stem cells

Although most broken bones can be mended with a firm cast and a generous measure of tender loving care, more complicated fractures require treatments like bone grafting.

16 Jun 2020

Two potent small molecules appear to suppress tumor growth in multiple cancers

City of Hope scientists have identified and developed two potent small molecules that appear to suppress tumor growth in multiple cancers even when other treatments cease to work, possibly due to the development of drug resistance.

16 Jun 2020

Scientists evaluate SARS-CoV-2 infection risks in livestock, poultry, pets and wildlife

A large-scale single-cell screening endeavor on a wide variety of animals showed that cells targeted by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are most abundant in cats, but are also found in other animals – unveiling a valuable resource for controlling the ongoing disruptive coronavirus disease (COVID-19) pandemic.

16 Jun 2020

Researchers develop a simple tool for making mouse models of COVID-19

Until there are effective treatments or vaccines, the COVID-19 pandemic will remain a significant threat to public health and economies around the world. A major hurdle to developing and testing new anti-viral therapies and vaccines for COVID-19 is the lack of good, widely available animal models of the disease.

16 Jun 2020

Research team generates comprehensive developmental map of human T-cells

Chintan Parekh, MD, of The Saban Research Institute of Children's Hospital Los Angeles, has led a team of investigators that generated a comprehensive roadmap for how T-cells develop in the human thymus.

16 Jun 2020

Severity of COVID-19 linked to heparanase activity and heparan sulfate levels

Researchers at Radboud University Medical Center in the Netherlands reported an increase of heparanase activity and heparan sulfate levels in the plasma of patients with coronavirus disease (COVID-19), which was also associated with the severity of the condition – suggesting, in turn, potential treatment utility of low molecular weight heparins. The paper is currently available on the medRxiv* preprint server.

16 Jun 2020

Persistent DNA damage in the placenta can affect embryonic growth

Scientists at the Stowers Institute for Medical Research have shown that a dysfunctional placenta can play a previously unrecognized role during the earliest stages of development in mouse models of Cornelia de Lange syndrome.

16 Jun 2020

T Cell News and Research

Latest T Cell News and Research

'Microbial dark matter' can affect cholesterol levels in humans

NTU researchers develop a sustainable way to extract high-quality antimicrobial compounds

Nanosponges could attack and neutralize SARS-COV-2 virus

An improved tetravalent antibody blocks SARS-CoV-2 infection

Researchers investigate how neural circuits enable the brain to regulate basal sighing

BioRescue consortium is developing new technologies to prevent the extinction of species

Mapping RNA sequences of therapeutic value in the SARS-CoV-2 genome

SARS-CoV-2 mutated spike proteins show variations in cell entry

Novel ACE2-antibody fusion molecules show anti-SARS-CoV-2 activity

Scientists isolate powerful SARS-CoV-2 -neutralizing antibodies from COVID-19 patients

Antibiotic X-206 effective against SARS-CoV-2 in vitro

How antibodies neutralize SARS-CoV-2 in convalescent patients

Anti-TNF drug preserves beta-cell function in newly diagnosed pediatric patients with Type 1 diabetes

Researchers create superior bone grafts using primitive stem cells

Two potent small molecules appear to suppress tumor growth in multiple cancers

Scientists evaluate SARS-CoV-2 infection risks in livestock, poultry, pets and wildlife

Researchers develop a simple tool for making mouse models of COVID-19

Research team generates comprehensive developmental map of human T-cells

Severity of COVID-19 linked to heparanase activity and heparan sulfate levels

Persistent DNA damage in the placenta can affect embryonic growth

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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