T Cell News and Research

Latest T Cell News and Research

Overcoming leukemia treatment resistance with nanoparticle drug delivery system

UConn associate professor of pharmaceutics Xiuling Lu, along with professor of chemistry Rajeswari M. Kasi, was part of a team that recently published a paper in Nature Cell Biology finding a commonly used chemotherapy drug may be repurposed as a treatment for resurgent or chemotherapy-resistant leukemia.

18 Jun 2020

Certain patients who receive hospital care for COVID-19 exhibit clear signs of brain injury

Certain patients who receive hospital care for coronavirus infection (COVID-19) exhibit clinical and neurochemical signs of brain injury, a University of Gothenburg study shows. In even moderate COVID-19 cases, finding and measuring a blood-based biomarker for brain damage proved to be possible.

18 Jun 2020

Sleeping less than normal can reduce positive feelings

"Not in the sense that we have more negative feelings, like being down or depressed. But participants in our study experienced a flattening of emotions when they slept less than normal. They felt less joy, enthusiasm, attention and fulfilment," says Associate Professor Ingvild Saksvik-Lehouillier at the Norwegian University of Science and Technology's (NTNU) Department of Psychology.

18 Jun 2020

Study identifies a previously unknown mechanism that contributes to intestinal cancer

A MedUni Vienna study group has identified a previously unknown mechanism involved in the development of intestinal cancer: The bacterial microbiome activates the so-called immune checkpoint Ido1 in Paneth cells, a special cell that is only found in the gastrointestinal tract, thereby preventing local intestinal inflammation.

18 Jun 2020

Novel biomarkers required to triage and monitor severely ill COVID-19 patients

Diagnostics company SphingoTec GmbH ("sphingotec") announced today the results of a working group meeting of clinical experts that discussed the utility of sphingotec's diagnostic solutions for acute and critical care in supporting the triage, diagnosis, and management of severely ill COVID-19 patients.

18 Jun 2020

Repurposing immunosuppressants to manage COVID-19

It might seem paradoxical to suggest immunosuppression could play a role in managing COVID-19. The seemingly logical therapeutic option for this disease would be an antiviral.

18 Jun 2020

Lonza and CELLINK collaborate to advance complete 3D cell culture workflows

Lonza and the Swedish company CELLINK have partnered to offer a comprehensive 3-dimensional bioprinting solution designed to optimize and increase access to complete 3D cell culture workflows.

18 Jun 2020

Scientists use CRISPR tool to make rapid, precise cuts in genomic material

In a series of experiments using human cancer cell lines, scientists at Johns Hopkins Medicine say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel known as CRISPR, and observe how specialized cell proteins repair the exact spot where the gene was cut.

18 Jun 2020

COVID-19 and blood group in aortic valve replacement

The COVID-19 pandemic has been found to cause disproportionate harm in patients with cardiovascular disease, especially among the elderly population, among other risk factors. However, a new study published on the preprint server medRxiv* in June 2020 is the first to report its clinical features in patients with aortic stenosis who have had a transcatheter aortic valve replacement (TAVR).

18 Jun 2020

Study paints clear picture of how a protein that calms brain activity works

As the body goes about its daily business, molecules called neurotransmitters control the level of electrical activity within the brain.

17 Jun 2020

Globally, 350 million could be at risk of severe COVID-19 and hospitalization

Now, a new study shows that one in five individuals is at risk of getting a severe case of COVID-19 due to the presence of underlying disease. The study appeared in the latest issue of The Lancet Global Health this week.

17 Jun 2020

Researchers use cellular nanosponges to soak up SARS-CoV-2

Scientists are working overtime to find an effective treatment for COVID-19, the illness caused by the new coronavirus, SARS-CoV-2.

17 Jun 2020

Researchers call for caution of using CAR-T immunotherapy against AML

Acute myeloid leukemia is a hematological malignancy which incidence increases with age, that is biologically, phenotypically, and genetically very heterogeneous.

17 Jun 2020

NJIT researchers develop new efficient method for targeted protein analysis

Researchers at New Jersey Institute of Technology in collaboration with Ohio University and Merck & Co. Inc. recently developed a new efficient method for targeted protein analysis -- one they say could speed up processes for disease testing, drug discovery and vaccine development.

17 Jun 2020

Integrin-binding peptide ATN-161: Potential COVID-19 treatment

Now, a new study by researchers at Tulane University and published on the preprint server bioRxiv* in June 2020 reports the potential role of an integrin inhibitor ATN-161 to prevent ACE2-S protein binding.

17 Jun 2020

USC researchers unlock fatal vulnerability in many cancer cells

Like any cells in the body, cancer cells need sugar - namely glucose - to fuel cell proliferation and growth.

17 Jun 2020

ACE2 and pattern recognition receptor genes increase with age

A recent study by researchers in California and published on the preprint server bioRxiv* in June 2020 shows that advancing age is associated with increased expression of pattern recognition receptor (PRR) genes and ACE2 receptors, possibly accounting in part for the increased severity of the disease in older adults.

17 Jun 2020

Highly conserved RNA structures are essential for SARS-CoV-2 replication and pathogenesis

A recent study from the University of North Carolina at Chapel Hill revealed how selective pressure helps in preserving secondary RNA structures in coronavirus genomes, unveiling a pivotal role of these elements in viral replication and pathogenesis. The paper is currently available on the bioRxiv* preprint server.

17 Jun 2020

Scientists examine SARS-CoV-2 cell entry in different species

Researchers in China have demonstrated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to interact with the host cell receptors of multiple species of animals.

17 Jun 2020

Iron fortification of bouillon or stock shows potential for tackling iron deficiency

Iron fortification of food is a cost-effective method of preventing iron deficiency. But finding iron compounds that are easily absorbed by the intestine without compromising food quality is a major challenge.

17 Jun 2020