T Cell News and Research

Latest T Cell News and Research

Study: Genes may play a far more complex role in oocyte maturation than previously assumed

Over the last six years a group of Estonian geneticists led by Associate Professor Agne Velthut-Meikas and a PhD student Ilmatar Rooda from TalTech Department of Chemistry and Biotechnology have studied genes previously associated primarily with female hormone synthesis and ovarian follicle development.

7 May 2020

SARS-CoV-2 in wastewater and rivers

A new study published on the preprint server medRxiv in May 2020 shows that while the virus causing COVID-19 may be present in wastewater and rivers, the biological agent is typically devoid of vitality and unable to cause active infection. This should provide some relief to public health authorities in their quest to contain the virus.

6 May 2020

Study discovers inhibition of SARS-CoV-2 entry priming protein by approved drug

The COVID-19 pandemic caused by the severe acute respiratory syndrome -coronavirus 2 (SARS-CoV-2) has spread to most of the world, causing millions of cases and hundreds of thousands of deaths. A new study published on the preprint server bioRxiv* shows that a protease inhibitor drug already approved by the Food and Drug Administration (FDA) could inhibit viral entry.

6 May 2020

Low CD8 and NK cell counts in the lung linked to high SARS-CoV-2 ACE2 receptor levels

A new study published on the preprint server bioRxiv in April 2020 reports that low levels of specific immune cells, namely, CD8 T cells and NK cells, are linked to higher expression of the ACE2 molecule, which acts as a receptor for the CoV.

6 May 2020

Research looks at best ways to disinfect N95 masks for reuse

The world is gripped by the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The health care personnel and those caring for these patients are at considerable risk of contracting the infection. N95 masks have been mentioned as protective face gear to cover the face, nose, and mouth of the user to prevent the spread of the infection via aerosols generated while coughing, sneezing, or even breathing.

6 May 2020

Spillover of more bat coronaviruses likely due to destruction of wildlife habitats

A new study available on the preprint server bioRxiv used phylogenetic analysis to demonstrate how certain groups of bats harbor multiple coronavirus lineages that are not readily transmitted across different bat taxa. However, the researchers caution that another novel human coronavirus outbreak originating from bats is imminent due to the destruction of wildlife habitats.

6 May 2020

Study identifies protein that acts like a volume dial for the release of neurotransmitters

Neuroscientists at MIT's Picower Institute for Learning and Memory have found that a protein acts like a volume dial for the release of neurotransmitters, the chemicals that neurons release across connections called synapses to stimulate muscles or communicate with other neurons in brain circuits.

6 May 2020

Study identifies protein vital for liver restoration and regeneration after transplant

Researchers from the Faculty of Medicine of the University of Barcelona and the CELLEX Biomedical Research Centre from IDIBAPS have identified in a study with mice a protein which is fundamental to guarantee the restoration and regeneration of the liver after a transplant or hepatic surgery.

6 May 2020

Interleukin-12 electroporation led to clinical responses in patients with advanced melanoma

Combining intratumoral electroporation of interleukin-12 (IL-12) DNA (tavokinogene telseplasmid, or TAVO) with the immune checkpoint inhibitor pembrolizumab (Keytruda) led to clinical responses in patients with immunologically quiescent advanced melanoma, according to results from a phase II trial.

6 May 2020

The Role of Microphysiological Systems for Oncology and Stem Cell Research

In this interview, Dr. Nancy Allbritton from The Allbritton Lab talks to News-Medical and Life Sciences about the revolutionary technology and techniques for the application of new technologies for oncology and stem cell research.

From Pittcon 6 May 2020

Human to Labskin Skin Models for Dermatology Research

A Human Skin Equivalent (HSE) skin model used for dermatology research, made from the same primary human cells but grown to a defined specification in a laboratory and not as complex as Human skin, lacking hair follicles and immune cells.

6 May 2020

GeoVax and Sino Biological establish exclusive supply agreement for research grade bioreagents related to SARS-CoV-2 (COVID-19) vaccine development

GeoVax Labs, Inc., a biotechnology company developing human vaccines and immunotherapies against infectious diseases and cancer, announced today that Beijing- and Philadelphia-based Sino Biological, Inc. will be its exclusive supplier of SARS-CoV-2 (COVID-19) bioreagent research products.

From Sino Biological Inc. 6 May 2020

OXGENE™ reports third consecutive year of 100% year on year revenue growth

OXGENE™ has more than doubled its annual revenue in the financial year just closed, in the third consecutive year of 100% year on year revenue growth.

From OXGENE 6 May 2020

Study: Genetics of AQP4 water channels impact the intensity of deep sleep

The reason why we sleep remains an unresolved question of the 21st century. Research by Sara Marie Ulv Larsen, Sebastian Camillo Holst and colleagues from the Neurobiology Research Unit at the University Hospital Copenhagen, published this week in the open access journal PLoS Biology, now shows that the depth of non-rapid-eye-movement (nonREM) sleep in humans is associated with different genetic versions of a gene that encodes a water channel involved in fluid flow in the brain.

6 May 2020

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

An international team led by Emory scientists has gained insight into the pathological mechanisms behind two devastating neurodegenerative diseases.

6 May 2020

New preclinical study shows promise for treating necrotizing enterocolitis

Necrotizing enterocolitis (NEC), a rare inflammatory bowel disease, primarily affects premature infants and is a leading cause of death in the smallest and sickest of these patients.

6 May 2020

Custom Parallel Reactor improves development of novel catalysts

The Chianese Organometallic Chemistry group at Colgate University are using a custom designed Multicell Parallel High-Pressure Reactor from Asynt to conduct reproducible hydrogenation experiments in parallel, to rapidly determine the kinetic properties of their novel catalysts.

From Asynt 6 May 2020

Is ACEI, ARB use linked to testing positive for COVID-19?

A new study published in the prestigious journal JAMA Cardiology in May 2020 reports that there is no association between the use of ACEIs/ARBs and testing positive for COVID-19. This supports current medical advice to continue using these drugs as indicated irrespective of the ongoing pandemic but indicates the need for more research to rule out any additional risk of severe illness due to these agents.

6 May 2020

Study provides more insight into the initiation and progression of human cancers

Volume 11, Issue 18 of @Oncotarget Clinical implications of chromatin accessibility assessed by ATAC-seq profiling in human cancers especially in a large patient cohort is largely unknown.

6 May 2020

Study provides evidence for safety and efficacy of chloroquine in COVID-19

After a pilot study (Huang et al.Journal of Molecular Cell Biology, in press), having proved the safety and effectiveness of the drug to reduce the viral RNA to undetectable levels in 10 COVID-19 patients, the researchers began this current study, published on the preprint server medRxiv.

5 May 2020

T Cell News and Research

Latest T Cell News and Research

Study: Genes may play a far more complex role in oocyte maturation than previously assumed

SARS-CoV-2 in wastewater and rivers

Study discovers inhibition of SARS-CoV-2 entry priming protein by approved drug

Low CD8 and NK cell counts in the lung linked to high SARS-CoV-2 ACE2 receptor levels

Research looks at best ways to disinfect N95 masks for reuse

Spillover of more bat coronaviruses likely due to destruction of wildlife habitats

Study identifies protein that acts like a volume dial for the release of neurotransmitters

Study identifies protein vital for liver restoration and regeneration after transplant

Interleukin-12 electroporation led to clinical responses in patients with advanced melanoma

The Role of Microphysiological Systems for Oncology and Stem Cell Research

Human to Labskin Skin Models for Dermatology Research

GeoVax and Sino Biological establish exclusive supply agreement for research grade bioreagents related to SARS-CoV-2 (COVID-19) vaccine development

OXGENE™ reports third consecutive year of 100% year on year revenue growth

Study: Genetics of AQP4 water channels impact the intensity of deep sleep

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

New preclinical study shows promise for treating necrotizing enterocolitis

Custom Parallel Reactor improves development of novel catalysts

Is ACEI, ARB use linked to testing positive for COVID-19?

Study provides more insight into the initiation and progression of human cancers

Study provides evidence for safety and efficacy of chloroquine in COVID-19

Immunology eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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