T Cell News and Research

Latest T Cell News and Research

Key antibiotic used for treating drug-resistant TB does not work as expected

Crick and Imperial researchers have found that a key antibiotic widely used to treat drug-resistant tuberculosis does not work as expected - a finding which could be used to develop new drugs.

16 Mar 2020

Researchers solve the riddle of superbug toxin damage to gut

A powerful Monash Biomedicine Discovery Institute (BDI) collaboration has revealed that a bacterial superbug can prevent stem cells in the gut from carrying out their vital role of regenerating the inner lining of the intestine.

16 Mar 2020

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Preclinical trials indicate that a drug candidate called OxaliTex can stop the growth of cancer cells completely. OxaliTex appears to be more potent than many other common chemotherapy drugs, with less toxicity and less rapidly counteracted by mechanisms of drug resistance. The study was reported in the journal Proceedings of the National Academy of Sciences in March 2020.

16 Mar 2020

'Natural killer' cells could help stop progression of Parkinson's disease

Researchers at the University of Georgia's Regenerative Bioscience Center and their colleagues have found that "natural killer" white blood cells could guard against the cascade of cellular changes that lead to Parkinson's disease and help stop its progression.

16 Mar 2020

Scientists find new way to amplify miRNA in live tumor cells for bioimaging

A good indicator of dysregulation in live cells is a change in their RNA expression. MicroRNA (miRNA), a special type of RNA, is considered a biomarker for carcinogenic cells.

16 Mar 2020

Researchers develop new kind of CRISPR screen technology to target RNA

CRISPR-based genetic screens have helped scientists identify genes that are key players in sickle-cell anemia, cancer immunotherapy, lung cancer metastasis, and many other diseases.

16 Mar 2020

Researchers discover a new mechanism of long-lasting pain relief

A group of researchers from Charité - Universitätsmedizin Berlin has discovered a new mechanism of long-lasting pain relief.

16 Mar 2020

Scientists discover link between Parkinson's and gene targeted by blue-green algae toxin

Scientists have discovered a possible link between Parkinson's disease and a gene impacted by a neurotoxin found in blue-green algae.

16 Mar 2020

Alzheimer's and its helper protein

It is commonly observed that the brain in patients with Alzheimer's disease (AD) often contains fibrils of tau protein, which build up within the brain neurons to interrupt proper communication between them. However, it is far from clear what these deposits mean and how they form.

15 Mar 2020

Bacteria multiply and grow into biofilms like settlers form cities

Microbiologists have long adopted the language of human settlement to describe how bacteria live and grow: They "invade" and "colonize." Relations dwelling in close proximity are "colonies."

13 Mar 2020

Researchers engineer microparticles that show promise against transplant rejection

Inspired by a tactic cancer cells use to evade the immune system, University of Pittsburgh researchers have engineered tiny particles that can trick the body into accepting transplanted tissue as its own.

13 Mar 2020

Research reveals how skin cells embark on a swift yet elaborate death

Skin is our body's most ardent defender against pathogens and other external threats. Its outermost layer is maintained through a remarkable transformation in which skin cells swiftly convert into squames--flat, dead cells that provide a tight seal between the living portion of the skin and the world outside.

13 Mar 2020

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Adaptive immunity is a powerful defense mechanism in vertebrates. A finely tuned interplay of different cell types provides a pathogen-specific immune response to eliminate for example bacteria and viruses.

13 Mar 2020

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

Oncotarget Volume 11, Issue 10 reported that dysregulation of noncoding micro RNA molecules has been associated with immune cell activation in the context of Helicobacter pylori-induced gastric inflammation as well as carcinogenesis, but also with downregulation of mismatch repair genes, and may interfere with immune checkpoint proteins that lead to the overexpression of antigens on gastric tumor cells.

13 Mar 2020

SPRK1 enzyme plays role in reorganizing the paternal genome during fertilization

A sperm enters an egg, an embryo develops and eventually a baby is born. But back up a second -- how does the mother's half-genome actually merge with the father's half-genome to form one new human genome?

13 Mar 2020

Tooth-enamel protein discovered in the eyes of people with dry AMD

A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration, according to a study from researchers at the National Eye Institute.

13 Mar 2020

Blood stem cells conserve epigenetic memory of previous infections to boost immunity

These findings should have a significant impact on future vaccination strategies and pave the way for new treatments of an underperforming or over-reacting immune system. The results of this research are published in Cell Stem Cell on March 12, 2020.

13 Mar 2020

NCAM2 protein is a vital factor in the formation of cerebral cortex, neuronal morphogenesis

The molecule NCAM2, a glycoprotein from the superfamily of immunoglobulins, is a vital factor in the formation of the cerebral cortex, neuronal morphogenesis and formation of neuronal circuits in the brain, as stated in the new study published in the journal Cerebral Cortex.

13 Mar 2020

Researchers reveal nerve circuitry regulating worms' response to changing temperatures

Nagoya University researchers and colleagues have revealed the nerve circuitry regulating the response of a tiny soil worm to changing temperatures.

13 Mar 2020

Single-drug therapy can attack several cellular targets using different modes of action

Clinicians combat the drug resistances of some cancer types by using a combination of different drugs. To make this approach more effective, chemists have designed a chemical conjugate that can simultaneously attack several cellular targets using different modes of action.

13 Mar 2020

T Cell News and Research

Latest T Cell News and Research

Key antibiotic used for treating drug-resistant TB does not work as expected

Researchers solve the riddle of superbug toxin damage to gut

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

'Natural killer' cells could help stop progression of Parkinson's disease

Scientists find new way to amplify miRNA in live tumor cells for bioimaging

Researchers develop new kind of CRISPR screen technology to target RNA

Researchers discover a new mechanism of long-lasting pain relief

Scientists discover link between Parkinson's and gene targeted by blue-green algae toxin

Alzheimer's and its helper protein

Bacteria multiply and grow into biofilms like settlers form cities

Researchers engineer microparticles that show promise against transplant rejection

Research reveals how skin cells embark on a swift yet elaborate death

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

SPRK1 enzyme plays role in reorganizing the paternal genome during fertilization

Tooth-enamel protein discovered in the eyes of people with dry AMD

Blood stem cells conserve epigenetic memory of previous infections to boost immunity

NCAM2 protein is a vital factor in the formation of cerebral cortex, neuronal morphogenesis

Researchers reveal nerve circuitry regulating worms' response to changing temperatures

Single-drug therapy can attack several cellular targets using different modes of action

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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