T Cell News and Research

Latest T Cell News and Research

Johns Hopkins researchers identify protein clumps in diseased hearts

Similar to how protein clumps build up in the brain in people with some neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure, according to a team led by Johns Hopkins University researchers.

9 May 2018

Changing metabolic states of intestinal bacteria have an effect on MAIT defense cells

A little-explored group of immune cells plays an important role in the regulation of intestinal bacteria.

9 May 2018

Disruption of the body's circadian rhythm linked to increased risk of breast cancer

For years, doctors have associated the BRCA1 and BRCA2 gene mutations with an increased risk of breast cancer.

9 May 2018

Tissue-engineered islets used to treat sudden-onset type 1 diabetes in mice

Researchers tissue-engineered human pancreatic islets in a laboratory that develop a circulatory system, secrete hormones like insulin and successfully treat sudden-onset type 1 diabetes in transplanted mice.

9 May 2018

Research findings could lead to new therapies to curb ovarian cancer metastasis

In order to spread their destruction, ovarian cancer cells must break free from their tumor home, travel through the fluid in the peritoneal cavity and attach to the outside of the abdominal organs--surfaces that are, by necessity, not sticky.

9 May 2018

Scientists develop computer algorithm that reveals gene networks activated in cancer cell

Recent headlines have cast suspicion on social network analysis, which can mine data from the internet to target advertisements or potentially influence elections.

9 May 2018

Potential stem cell treatment aids regeneration of heart muscle cells following heart attack

New research published in The Journal of Physiology has indicated a potential new stem cell treatment following a heart attack, by encouraging the regeneration of heart muscle cells. The low retention and survival rate of stem cells implanted in the heart had previously proven a sticking point for stem cell therapy following a heart attack.

9 May 2018

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

TRAIL, a member of the TNF family of ligands, causes caspase-dependent apoptosis through activation of its receptors, death receptor 4 and DR5.

9 May 2018

Findings confirm analytical principle that describes mutational processes and cancer development

When a cell develops into a tumor, something has gone terribly wrong: the uncontrolled growth, invasion of nearby tissues and finally metastasis are the result of many consecutive DNA mutations.

9 May 2018

Mutations in EBOV-Makona do not alter disease-causing ability in animal models, shows study

Early during the recent Ebola epidemic in West Africa, scientists speculated that the genetic diversity of the circulating Makona strain of virus (EBOV-Makona) would result in more severe disease and more transmissibility than prior strains.

9 May 2018

Researchers uncover the cause of scarring in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is one of the most challenging and frustrating diseases that pulmonologists face.

9 May 2018

Allen Institute for Cell Science launches first predictive and comprehensive, 3D model of live human cell

The Allen Institute for Cell Science today launched the first predictive and comprehensive, 3D model of a live human cell, the Allen Integrated Cell.

9 May 2018

New findings point to potential therapeutic avenues for leukemia

Scientists have known for decades that the Hox family of transcription factors are key regulators in the formation of blood cells and the development of leukemia.

9 May 2018

Centrosome amplification may contribute to initiation of cancers, research suggests

Cells begin to accumulate centrosomes - organelles that play a vital role during cell division - before they transform into cancer cells, according to a new study of patients with Barrett's esophagus condition, which is associated with esophageal cancer.

8 May 2018

Scientists discover how potential new drug targets spinal muscular atrophy

Spinal muscular atrophy (SMA) is a genetic disease that can leave infants with weak muscles and trouble breathing. Many with the disease die before age two. To help these patients, doctors need therapies that target the genetic mutation and stop its progression.

8 May 2018

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

A new study in Biological Psychiatry reports that dementia-related and psychiatric-related proteins cluster together to form aggregates in the brain, leading to abnormal cell function and behavior.

8 May 2018

Neon Therapeutics evaluates safety, efficacy of NEO-PV-01 in combination with KEYTRUDA and chemotherapy

Neon Therapeutics, a clinical-stage immuno-oncology company developing neoantigen-based therapeutics, today announced that it has treated the first patient in a clinical trial evaluating its proprietary personal neoantigen vaccine, NEO-PV-01, in combination with Merck's anti-PD-1 therapy, KEYTRUDA®, along with chemotherapy.

8 May 2018

T Cell News and Research

Latest T Cell News and Research

Johns Hopkins researchers identify protein clumps in diseased hearts

Changing metabolic states of intestinal bacteria have an effect on MAIT defense cells

Disruption of the body's circadian rhythm linked to increased risk of breast cancer

Tissue-engineered islets used to treat sudden-onset type 1 diabetes in mice

Research findings could lead to new therapies to curb ovarian cancer metastasis

Scientists develop computer algorithm that reveals gene networks activated in cancer cell

Potential stem cell treatment aids regeneration of heart muscle cells following heart attack

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

Findings confirm analytical principle that describes mutational processes and cancer development

Mutations in EBOV-Makona do not alter disease-causing ability in animal models, shows study

Researchers uncover the cause of scarring in idiopathic pulmonary fibrosis

Allen Institute for Cell Science launches first predictive and comprehensive, 3D model of live human cell

New findings point to potential therapeutic avenues for leukemia

Centrosome amplification may contribute to initiation of cancers, research suggests

Scientists discover how potential new drug targets spinal muscular atrophy

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

Neon Therapeutics evaluates safety, efficacy of NEO-PV-01 in combination with KEYTRUDA and chemotherapy

Researchers harness the precision of CRISPR to knock out single genes in yeast

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

PFKFB3 enzyme appears to play a key role in pulmonary hypertension

Immunology eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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