Thalassemia News and Research

Latest Thalassemia News and Research

“Chemical surgery” on embryos to free them of a gene causing thalassemia

A team of Chinese researchers have for the first time “mended” defective embryos using chemical surgery to free them of a faulty gene that leads to beta thalassemia. Until now this defect was found to be incorrigible caused due to a single misspelling in the DNA code. Beta thalassemia is a dreaded blood disorder wherein the child is unable to make healthy blood needing blood transfusions on a regular basis. The study was published this week in the journal Protein and Cell.

2 Oct 2017

Metabolism can impact host's susceptibility to develop malaria

Researchers from Instituto de Medicina Molecular Lisboa have found that the host's susceptibility to develop malaria depends on his or her metabolic state, which can be easily manipulated through external stimuli such as dietary patterns.

25 Sep 2017

Leeds Teaching Hospitals to introduce private stem cell collection and storage option for patients

The Leeds Teaching Hospitals NHS Trust is continually striving to provide high quality, patient centred care to each and every patient. Smart Cells International, in association with the trust, will be introducing the option for patients to privately store stem cells from the umbilical cord across St James’s University Hospital, Leeds General Infirmary and Wharfedale Hospital.

14 Sep 2017

Study provides insight into development of red blood cells

Every cell in the body, whether skin or muscle or brain, starts out as a generic cell that acquires its unique characteristics after undergoing a process of specialization. Nowhere is this process more dramatic than it is in red blood cells.

18 Aug 2017

Malaria already widespread on Sardinia in the Roman period, research shows

Malaria was already widespread on Sardinia by the Roman period, long before the Middle Ages, as indicated by research at the Institute of Evolutionary Medicine of the University of Zurich with the help of a Roman who died 2,000 years ago.

27 Jul 2017

US scientists make advances in modifying human embryos

American Scientists have managed to edit and improve the DNA of human embryos in an effort to correct the gene defects that cause inherited diseases.

27 Jul 2017

Infographic displays facts and information about stem cells, cord blood

Over 40,000 people have successfully stored stem cells with Smart Cells, however the industry is still relatively unknown and often subject to misinformation. In a bid to increase awareness and understanding of stem cell collection at birth, Smart Cells have created an informative infographic.

17 Jul 2017

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced an exclusive, global collaboration and license agreement for the development and commercialization of gene therapy programs for Hemophilia A, including SB-525, one of Sangamo's four lead product candidates, which Sangamo expects will enter the clinic this quarter.

11 May 2017

Researchers develop robust technique for efficient manufacture of red blood cells

Researchers have generated the first immortalised cell lines which allow more efficient manufacture of red blood cells.

23 Mar 2017

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

A team led by Pr. Marina Cavazzana conducted at Necker Children's Hospital, AP-HP and the Imagine Institute in October 2014 gene therapy in the context of a phase I clinical trial / II in a patient 13 years with severe sickle cell disease.

2 Mar 2017

Brazilian researchers propose new way for treating thalassemia major

Iron accumulation in myocardial cells, potentially resulting in heart failure or fatal arrhythmia, is one of the complications most feared by patients with thalassemia major, a hereditary disease also known as Mediterranean anemia.

7 Dec 2016

Epigem challenges Durham University students to develop diagnostic devices for rare anaemic conditions

Epigem, a high-tech British micro engineering company, has issued a blood challenge to students from the Durham University-led SOFI CDT (Centre for Doctoral Training in Soft Matter and Functional Interfaces).

17 Nov 2016

Yale researchers use new gene editing technique to correct mutations that cause thalassemia

A Yale-led research team used a new gene editing strategy to correct mutations that cause thalassemia, a form of anemia.

26 Oct 2016

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients.

12 Oct 2016

Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

An international team of scientists led by researchers at St. Jude Children's Research Hospital has found a way to use CRISPR gene editing to help fix sickle cell disease and beta-thalassemia in blood cells isolated from patients.

16 Aug 2016

New computer model shows how spleen filters misshapen red blood cells

Researchers, led by Carnegie Mellon University President Subra Suresh and MIT Principal Research Scientist Ming Dao, have created a new computer model that shows how tiny slits in the spleen prevent old, diseased or misshapen red blood cells from re-entering the bloodstream.

28 Jun 2016

Scientists develop non-toxic transplantation procedure using antibodies to target blood stem cells in mice

Harvard Stem Cell Institute scientists have taken the first steps toward developing a treatment that would make bone marrow - blood stem cell - transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and AIDS.

7 Jun 2016

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

New research suggests that synthetic peptides called minihepcidins may potentially treat two serious genetic blood diseases in children and adults. Although those diseases, beta-thalassemia and polycythemia vera, have opposite effects on red blood cell production, treating animals with minihepcidin helps to restore normal levels of red blood cells and reduces spleen enlargement. It also controls the accumulation of excess levels of iron in beta-thalassemia that often causes severe toxic effects.

9 May 2016

Key opinions leaders to discuss role of cyclophosphamide in the field of HSCT

Key opinions leaders in the field of haematopoetic stem cell transplantation (HSCT) will address the role of Cyclophosphamide, an anti-cancer chemotherapy drug, during the 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT) that will welcome more than 4,500 delegates in the host city of Valencia, Spain from the 3rd to the 6th of April 2016.

31 Mar 2016

Sangamo presents immunological data from SB-728-T HIV clinical study at CROI 2016

Sangamo BioSciences, Inc., the leader in therapeutic genome editing, announced the presentation of immunological data from the Company's clinical trials of SB-728-T, a ZFP Therapeutic designed to provide functional control of HIV.

25 Feb 2016

Thalassemia News and Research

Latest Thalassemia News and Research

“Chemical surgery” on embryos to free them of a gene causing thalassemia

Metabolism can impact host's susceptibility to develop malaria

Leeds Teaching Hospitals to introduce private stem cell collection and storage option for patients

Study provides insight into development of red blood cells

Malaria already widespread on Sardinia in the Roman period, research shows

US scientists make advances in modifying human embryos

Infographic displays facts and information about stem cells, cord blood

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Researchers develop robust technique for efficient manufacture of red blood cells

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

Brazilian researchers propose new way for treating thalassemia major

Epigem challenges Durham University students to develop diagnostic devices for rare anaemic conditions

Yale researchers use new gene editing technique to correct mutations that cause thalassemia

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

New computer model shows how spleen filters misshapen red blood cells

Scientists develop non-toxic transplantation procedure using antibodies to target blood stem cells in mice

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

Key opinions leaders to discuss role of cyclophosphamide in the field of HSCT

Sangamo presents immunological data from SB-728-T HIV clinical study at CROI 2016

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Thalassemia News and Research

Latest Thalassemia News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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