Toxicology News and Research

Latest Toxicology News and Research

Cequent Pharmaceuticals commences toxicology study of CEQ508 tkRNAi-based therapeutic candidate

Cequent Pharmaceuticals, a pioneer in the development of novel products to deliver RNAi-based treatments to prevent and treat human disease, has initiated a long-term (26-week) toxicology study of CEQ508 – the company's lead drug candidate based on its proprietary tkRNAi technology. This study is designed to enable a Phase II clinical trial slated for 2011. CEQ508 targets beta-catenin, a key oncogene implicated in the formation of colonic polyps and in the progression of polyps to colorectal cancer.

16 Apr 2010

UALR researcher receives federal grant to track estrogen-mimicking compounds in consumer products

Dr. Jerry Darsey, professor of chemistry in UALR's College of Science and Mathematics, has received $77,000 from a federal Food and Drug Administration grant to develop methods to track estrogen mimicking compounds in various products and assess how use of the products affect women.

16 Apr 2010

3M Drug Delivery Systems grows its product portfolio in Asia’s pharmaceutical industry

3M Drug Delivery Systems recently advanced its participation in the Asian market with a sponsorship of the Asia Pharma R&D Leaders 2010 event, held March 4 and 5 in Shanghai, China.

16 Apr 2010

Current screening methods for FOBT are often not appropriate

More than 75 percent of primary care physicians in the United States who order or perform the fecal occult blood test as a screening option for colorectal cancer perform an in-office test rather than relying on the home-based test, even though the home-based test is more accurate, a study by the Centers for Disease Control and Prevention has found.

16 Apr 2010

UA Superfund Research Program to study contaminated dust, water and health issues

Metal-laden dust and contaminated water, and their health effects, will be the focus of multiple projects for the University of Arizona's Superfund Research Program during the next five years. The National Institutes of Environmental Health Sciences recently notified UA that the Superfund Research Program, funded since 1989, will receive an additional $14 million in grant funding through 2015 to conduct the research.

15 Apr 2010

Dual evacuation following noxious gas leak

According to the Public Services Association there has been a constant leak of noxious fumes from a Newcastle office building for years and the source needs to be identified. The building has RTA call centre staff and Commonwealth Bank customer service representatives as its tenants.

14 Apr 2010

Researchers may be one step closer to slowing the progression of Alzheimer's disease

Researchers may be one step closer to slowing the onset and progression of Alzheimer's disease. An animal study supported by the National Institute of Environmental Health Sciences, part of the National Institutes of Health, shows that by targeting the blood-brain barrier, researchers are able to slow the accumulation of a protein associated with the progression of the illness.

13 Apr 2010

NIAID funds second study of Aeolus Pharmaceuticals' AEOL 10150 as potential countermeasure to GI-ARS

Aeolus Pharmaceuticals, Inc. announced today that a second study of its lead drug, AEOL 10150, has been initiated by the National Institutes of Health's (NIH), National Institute of Allergy and Infectious Diseases (NIAID) Radiation/Nuclear Medical Countermeasures development program as a countermeasure for radiation exposure to the gastrointestinal (GI) tract.

13 Apr 2010

Hunter Valley cancer cluster report to be made public

Cancer cases may have manifested as brain tumors in the local population in Upper Hunter Valley as a result of pollution from mines and power stations. With five residents in a single block in Singleton being diagnosed with brain tumors a public inquiry to establish just how harmful dust and toxins from the mines and power stations are had been constituted by the state government.

13 Apr 2010

Triclosan antibacterial found in soap in the spotlight

If a chemical is banned in other countries and by the European Union, it does merit a study by the FDA, even if there is no existing study to suggest that it is harmful to humans. While there may be no current evidence available that triclosan is hazardous to humans, it has been linked to hormone alterations in animals.

9 Apr 2010

Potential toxicity of zinc nanoparticles in sunscreen products

Scientists are reporting that particle size affects the toxicity of zinc oxide, a material widely used in sunscreens. Particles smaller than 100 nanometers are slightly more toxic to colon cells than conventional zinc oxide. Solid zinc oxide was more toxic than equivalent amounts of soluble zinc, and direct particle to cell contact was required to cause cell death. Their study is in ACS' Chemical Research in Toxicology, a monthly journal.

8 Apr 2010

Scientific evidence links high levels of copper and iron to age-related disorders

With scientific evidence linking high levels of copper and iron to Alzheimer's disease, heart disease, and other age-related disorders, a new report in ACS' Chemical Research in Toxicology suggests specific steps that older consumers can take to avoid build up of unhealthy amounts of these metals in their bodies.

8 Apr 2010

9/11 rescue teams’ lungs still affected and aged by 12 years: say researchers

In a published report in the prestigious New England Journal of Medicine this Wednesday researchers revealed that fire fighters and rescue workers who assisted in the aftermath of the World Trade Center attacks on September 11, 2001 had compromised lung function even seven years after the incident.

8 Apr 2010

Children with FASD show high prevalence of developing epilepsy

Children with Fetal Alcohol Spectrum Disorder show a very high prevalence of developing epilepsy and having seizures, according to a national study by Queen's University researchers.

7 Apr 2010

Ricerca Biosciences, Life Science Partner announce business development agreement

Ricerca Biosciences, a preclinical contract research drug development company, is pleased to announce a business development agreement with Life Science Partner (LSP) Co., Ltd., of Tokyo, Japan. Ricerca offers a unique spectrum of services for the areas of agrochemical registration, environmental analysis and pre-investigational new drug (IND) biopharmaceutical registration.

1 Apr 2010

PolyMedix secures $14M credit facility with Hercules Technology II

PolyMedix, Inc., an emerging biotechnology company focused on developing new therapeutic drugs to treat acute cardiovascular disorders and infectious diseases, has secured a $14 million credit facility with Hercules Technology II, L.P., an affiliate of Hercules Technology Growth Capital, Inc.

1 Apr 2010

Metabolon awarded U.S. patents for metabolomics methods

Metabolon, Inc., the leader in global metabolism through biomarker discovery and analysis, announced today the grant of US Patent 7,682,783 and US Patent 7,682,784 entitled "Methods for Drug Discovery, Disease Treatment and Diagnosis Using Metabolomics". The USPTO awarded the patents to Metabolon on March 23, 2010. The issued claims in the new patents are for uses of metabolomics to identify diagnostic biomarkers for depression and schizophrenia by profiling classes of metabolites in a sample.

1 Apr 2010

LAB Research reports 9% decrease in revenues for 2009

LAB Research Inc., a global Canadian-based non-clinical contract research organization, today announced its fourth quarter and 2009 year-end financial results.

1 Apr 2010

Cell study may yield new treatment strategies for debilitating diseases

A Los Alamos National Laboratory toxicologist and a multidisciplinary team of researchers have documented potential cellular damage from "fullerenes"-soccer-ball-shaped, cage-like molecules composed of 60 carbon atoms. The team also noted that this particular type of damage might hold hope for treatment of Parkinson's disease, Alzheimer's disease, or even cancer.

1 Apr 2010

Researchers evaluate the effect of chemical cocktails on humans and the environment

Throughout our lives we are exposed to an enormous range of man-made chemicals, from food, water, medicines, cosmetics, clothes, shoes and the air we breathe. At the request of the EU, researchers at the University of Gothenburg, Sweden, have looked at the risk of "chemical cocktails" and have proposed a number of measures that need to be implemented in the current practice of chemical risk assessment.

29 Mar 2010

Toxicology News and Research

Latest Toxicology News and Research

Cequent Pharmaceuticals commences toxicology study of CEQ508 tkRNAi-based therapeutic candidate

UALR researcher receives federal grant to track estrogen-mimicking compounds in consumer products

3M Drug Delivery Systems grows its product portfolio in Asia’s pharmaceutical industry

Current screening methods for FOBT are often not appropriate

UA Superfund Research Program to study contaminated dust, water and health issues

Dual evacuation following noxious gas leak

Researchers may be one step closer to slowing the progression of Alzheimer's disease

NIAID funds second study of Aeolus Pharmaceuticals' AEOL 10150 as potential countermeasure to GI-ARS

Hunter Valley cancer cluster report to be made public

Triclosan antibacterial found in soap in the spotlight

Potential toxicity of zinc nanoparticles in sunscreen products

Scientific evidence links high levels of copper and iron to age-related disorders

9/11 rescue teams’ lungs still affected and aged by 12 years: say researchers

Children with FASD show high prevalence of developing epilepsy

Ricerca Biosciences, Life Science Partner announce business development agreement

PolyMedix secures $14M credit facility with Hercules Technology II

Metabolon awarded U.S. patents for metabolomics methods

LAB Research reports 9% decrease in revenues for 2009

Cell study may yield new treatment strategies for debilitating diseases

Researchers evaluate the effect of chemical cocktails on humans and the environment

Forensics And Toxicology eBook

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Toxicology News and Research

Latest Toxicology News and Research

Forensics And Toxicology eBook

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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