Toxicology News and Research

Latest Toxicology News and Research

Chelsea initiates NORTHERA Phase III trial for symptomatic NOH associated with PD

Chelsea Therapeutics International, Ltd. announced the initiation of Study 306, a pivotal Phase III trial evaluating the efficacy of NORTHERA™, an oral synthetic precursor of norepinephrine, for the treatment of symptomatic neurogenic orthostatic hypotension (NOH) associated with Parkinson's disease.

29 Jun 2010

JANUMET results in greater blood sugar reductions in patients with type 2 diabetes compared to pioglitazone

New data were presented at the American Diabetes Association 70th Annual Scientific Sessions from a study comparing JANUMET (sitagliptin/metformin) to pioglitazone. In this study, JANUMET resulted in significantly greater blood sugar reductions in patients with type 2 diabetes compared with pioglitazone.

28 Jun 2010

Florida seeks new tools to stop dengue outbreak

While all eyes are on the Gulf oil spill, another natural disaster worsens as Key West Florida battles the first U.S. outbreak of dengue in 75 years. With over 30 confirmed cases (27 in 2009, 8 in 2010) and 5% of residents showing exposure to the mosquito-spread disease, Florida is seeking new tools to stop the emerging threat. Aiming to enhance their existing control program, the Florida Keys Mosquito Control District turned to SpringStar Inc in Woodinville, WA.

28 Jun 2010

CHMP adopts positive opinion on pending MAA for SYCREST sublingual tablets

Merck announced that the Committee for Medicinal Products for Human Use adopted a positive opinion on the pending Marketing Authorization Application for SYCREST (asenapine) sublingual tablets. The CHMP has recommended that the European Commission grant a marketing authorization for SYCREST for the treatment of moderate to severe manic episodes associated with bipolar I disorder in adults. The CHMP did not support an indication for the treatment of schizophrenia.

25 Jun 2010

Scientists report potential toxicity of nanoparticles in consumer products

Scientists are reporting that particle size affects the toxicity of zinc oxide, a material widely used in sunscreens. Particles smaller than 100 nanometers are slightly more toxic to colon cells than conventional zinc oxide. Solid zinc oxide was more toxic than equivalent amounts of soluble zinc, and direct particle to cell contact was required to cause cell death.

25 Jun 2010

Merck's DULERA Inhalation Aerosol for asthma receives FDA approval

Merck today announced that the U.S. Food and Drug Administration (FDA) has approved DULERA® (mometasone furoate and formoterol fumarate dihydrate) Inhalation Aerosol, a new fixed-dose combination asthma treatment for patients 12 years of age and older. DULERA is not indicated for the relief of acute bronchospasm. DULERA combines an inhaled corticosteroid (mometasone furoate) with a long-acting beta2-agonist (formoterol fumarate).

24 Jun 2010

Entelos agree to the terms of non-exclusive perpetual license to Metabolism Physiolab platform for Pfizer

Entelos, Inc. announced today that it has agreed to the terms of a non-exclusive perpetual license to its Metabolism Physiolab platform for Pfizer Inc. The perpetual license will include access for Pfizer to Entelos' PhysioLab Modeler software and its PhysioLab Simulation Server.

24 Jun 2010

Ricerca's Lyon facility obtains ISO 9001:2008 certification

Ricerca Biosciences, a uniquely integrated preclinical contract research drug development company providing services to the pharmaceutical industry, is pleased to announce that its Ricerca France, Lyon facility, has recently obtained the ISO 9001:2008 certification for all activities performed at the site.

22 Jun 2010

NCI awards GeneGo Phase II SBIR grant for development of MetaMiner(Oncology) platform

GeneGo, Inc., a leading provider of databases, software and services in systems biology and chemistry, announced today that they were awarded with a Phase II SBIR grant from the National Cancer Institute (NCI) for further development of an analytical platform for translational research and data analysis in oncology.

22 Jun 2010

Cytochrome P450 plays important role in management of high blood pressure: Researchers

Researchers have found that increasing certain proteins in the blood vessels of mice, relaxed the vessels, lowering the animal's blood pressure. The study provides new avenues for research that may lead to new treatments for hypertension.

22 Jun 2010

Star Scientific seeks FDA approval of Stonewall-BDL as "modified risk tobacco product"

Star Scientific, Inc. announced that on Friday, June 18 the company filed an application with the Food & Drug Administration for approval to market Stonewall-BDL™ as a "modified risk tobacco product" under the Family Smoking Prevention and Tobacco Control Act of 2009. This is Star's second such application to the Tobacco Products Center of the FDA, which has been established to oversee all aspects of tobacco regulation outlined in the 2009 Act.

22 Jun 2010

Celator announces expansion of research agreement with Cephalon

Celator Pharmaceuticals today announced that it has expanded its research agreement with Cephalon, Inc.. The research agreement provides for the utilization of Celator's proprietary technology in an ongoing drug development and life-cycle management program at Cephalon.

22 Jun 2010

New Zealanders sucking in more nicotine per cigarette than most other smokers worldwide

Smokers in New Zealand are taking in more nicotine than Australians says a new study. The study found that smokers there have a distinct preference for high nicotine containing brands of cigarettes and have the greatest average amount of tar exposure out of 5,703 smokers in eight countries. Where Australians took 1.36mg of nicotine per cigarette, New Zealanders took in 1.62mg.

21 Jun 2010

Millar, Telemetry Research partner to offer TRM53P implantable transmitters

Millar Instruments, Inc., a medical device manufacturing firm and developer of pressure sensing technology, has released the TRM53P implantable transmitter through the partnership with Telemetry Research, Ltd. The TRM53P is the world's first, fully implantable transmitter that combines Millar's gold standard solid-state pressure sensors with Telemetry Research's next generation telemetry technology.

21 Jun 2010

LIVALO for primary hyperlipidemia or mixed dyslipidemia now available in U.S.

Kowa Pharmaceuticals America, Inc., and Eli Lilly and Company today announced that LIVALO® (pitavastatin) tablets is now available in retail pharmacies throughout the United States. LIVALO, a statin medication approved by the U.S. Food and Drug Administration (FDA) in August 2009 is indicated for adults as an adjunctive therapy to diet for the treatment of primary hyperlipidemia or mixed dyslipidemia. LIVALO is available in doses of 1 mg, 2 mg and 4 mg.

21 Jun 2010

Research findings support the need to establish standards for DFSA care

New toxicology findings reveal the presence of drugs and/or alcohol in 76 per cent of women and men who suspect they were victims of drug-facilitated sexual assault. Of those, 64 per cent did not report voluntarily consuming the drugs found, supporting their belief that they may have been slipped a drug. In addition, unexpected male DNA was found in a substantial number of cases, confirming sexual activity.

19 Jun 2010

Akela Pharma first-quarter net loss reduces to $0.4 million

Akela Pharma, Inc., a leader in the development of therapeutics for the treatment of pain, and the company's wholly owned subsidiary, PharmaForm, today announced its financial results for the three months ended March 31, 2010.

19 Jun 2010

ActiveCare, Vista Therapeutics announce strategic relationship to develop Nano Biosensors for seniors

ActiveCare, Inc. and Vista Therapeutics, Inc. announced today a strategic relationship to develop Nano Biosensors for ActiveCare's products and services to be utilized by the elderly. These Biosensors will allow ActiveCare to continuously monitor specific chronic diseases commonly occurring in the elderly and thus preventively predict and avoid acute medical events. "This technology is designed to prolong and improve the quality of life of our senior population," stated James Dalton, President of ActiveCare.

18 Jun 2010

Researchers study risks and consequences of cigarette smoking in people living in multiple-unit housing

In an effort to protect children from harmful tobacco smoke exposure, health and medical professionals are pushing for a ban on smoking in public housing in a report appearing in this week's New England Journal of Medicine.

18 Jun 2010

Ricerca announces services under U.S. DEA license

Ricerca Biosciences, an industry-leading, integrated preclinical contract research organization (CRO) providing services to the chemical and biopharmaceutical industries, is pleased to announce services it can now provide under its United States Drug Enforcement Administration (DEA) license.

18 Jun 2010

Toxicology News and Research

Latest Toxicology News and Research

Chelsea initiates NORTHERA Phase III trial for symptomatic NOH associated with PD

JANUMET results in greater blood sugar reductions in patients with type 2 diabetes compared to pioglitazone

Florida seeks new tools to stop dengue outbreak

CHMP adopts positive opinion on pending MAA for SYCREST sublingual tablets

Scientists report potential toxicity of nanoparticles in consumer products

Merck's DULERA Inhalation Aerosol for asthma receives FDA approval

Entelos agree to the terms of non-exclusive perpetual license to Metabolism Physiolab platform for Pfizer

Ricerca's Lyon facility obtains ISO 9001:2008 certification

NCI awards GeneGo Phase II SBIR grant for development of MetaMiner(Oncology) platform

Cytochrome P450 plays important role in management of high blood pressure: Researchers

Star Scientific seeks FDA approval of Stonewall-BDL as "modified risk tobacco product"

Celator announces expansion of research agreement with Cephalon

New Zealanders sucking in more nicotine per cigarette than most other smokers worldwide

Millar, Telemetry Research partner to offer TRM53P implantable transmitters

LIVALO for primary hyperlipidemia or mixed dyslipidemia now available in U.S.

Research findings support the need to establish standards for DFSA care

Akela Pharma first-quarter net loss reduces to $0.4 million

ActiveCare, Vista Therapeutics announce strategic relationship to develop Nano Biosensors for seniors

Researchers study risks and consequences of cigarette smoking in people living in multiple-unit housing

Ricerca announces services under U.S. DEA license

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Toxicology News and Research

Latest Toxicology News and Research

Forensics and toxicology - Industry Focus eBook eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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