Toxicology News and Research

Latest Toxicology News and Research

Scientists develop inexpensive method for determining chemicals that may cause skin allergies

Scientists are reporting development of a fast, simple, inexpensive method for determining whether chemicals in consumer products and workplaces may cause skin allergies in people -- a method that does not involve use of animals. Their study appears in ACS' Chemical Research in Toxicology, a monthly journal.

27 May 2010

ADDF provides $248,000 grant to ALSP to allow its lead drug candidate towards clinical trials

The Alzheimer's Drug Discovery Foundation announced today that it is providing a grant of $248,000 to American Life Science Pharmaceuticals, Inc. to allow for manufacture of its lead drug candidate to be used in preclinical toxicology testing in preparation for entering Phase I clinical trials early in 2011.

25 May 2010

Lytix Biopharma receives approval to initiate Phase I/IIa clinical trial of Lytixar for MRSA

The Norwegian pharmaceutical company Lytix Biopharma AS today announces the approval by the Swedish Medical Products Agency to commence a Phase I/IIa clinical trial with Lytixar (LTX-109) for nasal decolonisation of MRSA.

24 May 2010

New drug testing technique is safe and effective

A new study from the Swedish medical university Karolinska Institutet presents a new technique that makes drug testing possible through exhaled air for the first time.

21 May 2010

NeuroTherapeutics Pharma closes $43 million Series B financing round

NeuroTherapeutics Pharma, Inc. (NTP), a biopharmaceutical company focused on developing novel therapies for central nervous system (CNS) disorders, announced today that it closed a $43 million Series B financing. New investors include Fidelity Biosciences, MPM Capital and SR One, who co-led the transaction, and Pfizer, Inc. Existing investors Novo Ventures and Thomas McNerney & Partners also participated in the round.

20 May 2010

UAMS and partners receive $14.7M NIH grant for extension of biomedical research

Biomedical research in Arkansas has received a $14.7 million boost over five years from the National Institutes of Health (NIH) to continue expanding and improving biomedical research in the state.

20 May 2010

Study presents new technique that makes drug testing possible through exhaled air

A new study from the Swedish medical university Karolinska Institutet presents a new technique that makes drug testing possible through exhaled air for the first time. By examining people who had received emergency care for an amphetamine overdose, the researchers found that in all cases there were traces of amphetamine and metamphetamine in the exhaled breath.

19 May 2010

International Stem Cell announces strategic alliance with TAP

International Stem Cell Corporation, www.intlstemcell.com, announced today that it had entered into a strategic alliance with The Automation Partnership, www.automationpartnership.com, to automate and scale up the production of stem cell-derived human corneal tissue.

18 May 2010

genOway and Griffith University sign research partnership and license for olfactory stem cells technology

genOway, the biotechnology company dedicated to the development of genetically modified animal models, today reports an agreement with the Griffith University (Brisbane, Australia) on a eight-months research partnership with its Eskitis Institute for Cell and Molecular Therapies focusing on autologous olfactory adult stem cells. This research program is coupled with a world wide exclusive license to genOway for the rodent transgenic business.

17 May 2010

Study identifies potential noninvasive biomarkers in NAFLD, NASH using Metabolon's platform

Metabolon, Inc. announces a study published in the Metabolism Journal released in the paper on April 28, 2010, by Satish C. Kalhan.

17 May 2010

Caliper Life Sciences' CDAS unit awarded new funding commitment for EPA ToxCast screening program

Caliper Life Sciences, Inc., a leading provider of tools and services for drug discovery and life sciences research, today announced that its Caliper Discovery Alliances and Services (CDAS) unit has been awarded a new funding commitment for $2.9 million under its contract with the Environmental Protection Agency for the EPA's ToxCast screening program.

14 May 2010

EPA continues to validate ToxCast screening tool by testing more than 100 drugs

The U.S. Environmental Protection Agency will continue validating its ToxCast screening tool by screening more than 100 drugs provided by Pfizer, GlaxoSmithKline, Sanofi-Aventis, and Merck. These drugs never entered the marketplace because they demonstrated different types and levels of toxicity when the pharmaceutical companies conducted the early stage clinical trials required by the Food and Drug Administration as part of the drug development process.

14 May 2010

Scientists study impact of Hurricane Katrina on ecology, human health

Scientists studying the environmental impact of Hurricane Katrina on the Gulf Coast of Louisiana and the city of New Orleans have revealed the ecological impact and human health risks from exposure to chemical contaminants. The findings, published in a special issue of Environmental Toxicology and Chemistry, demonstrate how Hurricane Katrina caused significant ecological damage by altering coastal chemistry and habitat.

14 May 2010

Chimerix commences first-in-human study of CMX157 for HIV

Chimerix, Inc., a biotechnology company developing orally-available antiviral therapeutics, announced the commencement of a first-in-human study of CMX157, a novel lipid conjugate of the nucleotide tenofovir with in vitro activity against both tenofovir-sensitive and tenofovir-resistant human immunodeficiency virus (HIV). CMX157 has the potential to increase efficacy and decrease toxicity as compared to tenofovir, and may enable the creation of new 'one pill, once-a-day', fixed-dose combination regimens for the treatment of HIV infection.

14 May 2010

NiKem Research receives Italian authorization to perform toxicology studies of NCEs in rodents

NiKem Research is pleased to announce that it has received on March 29th 2010, from the Italian Ministry of Health (Decree N. 69/2010-B), the authorization to perform acute and sub-chronic toxicology studies (upto 28 days) in all rodent species for preliminary safety evaluation of novel chemical entities (NCEs). Toxicokinetic (TK) studies are also allowed to correlate plasma and/or organ exposure of NCEs (and metabolites) to tolerated doses in toxicology studies.

12 May 2010

Anavex reports promising results from ANAVEX 2-73 Alzheimer's disease compound in animal studies

Anavex Life Sciences Corp. is pleased to report promising results from animal studies with ANAVEX 2-73, the company's lead compound for the treatment and modification of Alzheimer's disease.

5 May 2010

NOXXON Pharma completes first-in-human clinical trial with Spiegelmer NOX-A12

NOXXON Pharma AG, the biopharmaceutical company focusing on the development of novel drugs based on its unique proprietary Spiegelmer® technology, announced today the successful completion of the first-in-human clinical trial with Spiegelmer® NOX-A12.

3 May 2010

Searchable database on chemical hazard, exposure and toxicity data now available

The U.S. Environmental Protection Agency is making it easier to find chemical information online. EPA is releasing a database, called ToxRefDB, which allows scientists and the interested public to search and download thousands of toxicity testing results on hundreds of chemicals.

3 May 2010

NIEHS doctor to discuss impact of climate change on children's health

John Balbus, MD, MPH, Senior Advisor for Public Health at the National Institutes of Environmental Health Sciences (NIEHS), will discuss the significant public health threats and opportunities presented by climate change and how children around the world may be affected.

3 May 2010

CBC, Scarab Genomics form agreement to increase manufacturing yield of Solinex rhu-pGSN

Critical Biologics Corporation (CBC) and Scarab Genomics announced today a strategic agreement to substantially increase the manufacturing yield of CBC's lead therapeutic protein candidate, Solinex™, an intravenous formulation of recombinant human plasma gelsolin (rhu-pGSN).

30 Apr 2010

Toxicology News and Research

Latest Toxicology News and Research

Scientists develop inexpensive method for determining chemicals that may cause skin allergies

ADDF provides $248,000 grant to ALSP to allow its lead drug candidate towards clinical trials

Lytix Biopharma receives approval to initiate Phase I/IIa clinical trial of Lytixar for MRSA

New drug testing technique is safe and effective

NeuroTherapeutics Pharma closes $43 million Series B financing round

UAMS and partners receive $14.7M NIH grant for extension of biomedical research

Study presents new technique that makes drug testing possible through exhaled air

International Stem Cell announces strategic alliance with TAP

genOway and Griffith University sign research partnership and license for olfactory stem cells technology

Study identifies potential noninvasive biomarkers in NAFLD, NASH using Metabolon's platform

Caliper Life Sciences' CDAS unit awarded new funding commitment for EPA ToxCast screening program

EPA continues to validate ToxCast screening tool by testing more than 100 drugs

Scientists study impact of Hurricane Katrina on ecology, human health

Chimerix commences first-in-human study of CMX157 for HIV

NiKem Research receives Italian authorization to perform toxicology studies of NCEs in rodents

Anavex reports promising results from ANAVEX 2-73 Alzheimer's disease compound in animal studies

NOXXON Pharma completes first-in-human clinical trial with Spiegelmer NOX-A12

Searchable database on chemical hazard, exposure and toxicity data now available

NIEHS doctor to discuss impact of climate change on children's health

CBC, Scarab Genomics form agreement to increase manufacturing yield of Solinex rhu-pGSN

Forensics and toxicology - Industry Focus eBook eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

Toxicology News and Research

Latest Toxicology News and Research

Forensics and toxicology - Industry Focus eBook eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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