Toxicology News and Research

Latest Toxicology News and Research

Research identifies early biomarker for insulin resistance, glucose intolerance in nondiabetic population

Metabolon, Inc., the leader in metabolomics-based biomarker discovery and analysis, today announced the publication of research that identified a novel, early biomarker for insulin resistance and glucose intolerance in a nondiabetic population.

17 Jun 2010

Smokeless tobacco affects normal function of CYP-450 family of enzymes: Report

Far from having adverse effects limited to the mouth, smokeless tobacco affects the normal function of a key family of enzymes found in almost every organ in the body, according to the first report on the topic in ACS' monthly journal Chemical Research in Toxicology. The enzymes play important roles in production of hormones, including the sex hormones estrogen and testosterone; production of cholesterol and vitamin D; and help the body breakdown prescription drugs and potentially toxic substances.

17 Jun 2010

Hamilton Thorne announces launch of Staccato multi-pulse laser system at 8th ISSCR Annual Meeting

Hamilton Thorne Ltd., a leading provider of advanced laser systems and instruments for the stem cell research and fertility clinic markets, today announced the launch of the Staccato(TM) multi-pulse laser system at the 8th Annual Meeting of the International Society of Stem Cell Research (ISSCR), June 16-19, 2010, in San Francisco, CA. Staccato(TM) will add to the functionality of the XYClone(R) laser system, providing the ability of near-continuous application of the laser to the sample through rapid pulsing of the beam.

16 Jun 2010

CDI, Promega enter collaboration for toxicity testing in drug discovery process

Cellular Dynamics International (CDI) and Promega have entered into a research collaboration with the goal of bringing more relevant and highly predictive toxicity testing to the drug discovery process. Pharmaceutical discovery scientists will now be able to combine bioassays with human cardiomyocytes to improve prediction of unintentional, detrimental side effects that have previously remained undetected until late in the development process or after release of the drug to the general public.

15 Jun 2010

Asterand subsidiary BioSeek signs agreement with Amylin

Asterand plc, a leading provider of human tissue and human tissue-based research services to pharmaceutical and biotechnology companies engaged in drug discovery, today announces that its subsidiary BioSeek, LLC, a pioneer in the application of predictive human biology to drug discovery, has signed a one-year collaboration agreement with Amylin Pharmaceuticals, Inc.

14 Jun 2010

Helix BioPharma third-quarter revenues increase 20.6%

Helix BioPharma Corp. today announced financial results for the third quarter ended April 30, 2010.

11 Jun 2010

CPL Biologicals completes construction of vaccine facility in Dholka, India

CPL Biologicals (CPLB), a joint venture of Cadila Pharmaceuticals Ltd. and Novavax, Inc., today announced that it has completed construction of its vaccine facility in Dholka, India and will commence equipment and installation validation this month so that the facility conforms to global standards for production of vaccines for human use.

10 Jun 2010

MicroConstants adds second Waters Xevo TQ MS system

MicroConstants, Inc., a bioanalytical and pharmacokinetic-specialty Contract Research Organization (CRO) in San Diego, California, announces the continued expansion of its bioanalytical capacity through the addition of a second Waters Xevo TQ MS system. The CRO has also appointed a new East Coast business development manager to actively pursue new business opportunities in that region.

10 Jun 2010

Repligen's fiscal 2010 total revenue decreases to $20,971,000

Repligen Corporation today reported results for the fourth quarter and fiscal year 2010, ended March 31, 2010. Total revenue for the year was $20,971,000 compared to total revenue of $29,362,000 for fiscal year 2009 ended March 31, 2009.

9 Jun 2010

Lytix Biopharma, KAEL-GemVax granted approval for GV1001/LTX-315 combination cancer therapy study

The Norwegian biopharmaceutical company Lytix Biopharma and Korean company KAEL-GemVax today announced approval by the Norwegian Medicines Agency ('Statens Legemiddelverk') to test a combination of LTX-315 and GV1001 as vaccine therapy in patients with resected tumours. Lytix Biopharma CEO Gunnar Salid states, "We are delighted to announce the approval of our joint study to test a combination of two very interesting experimental drugs.

9 Jun 2010

Waste incinerator spewing chemical waste: Says worried Brisbane Lord Mayor

A council commissioned study into the Ace Waste incinerator at Willawong showed that the residents and businesses around the facility were at potential risk of exposure to chemical emissions. The incinerator at Willawong is used to dispose of medical and chemical pollutants that can cause cancer when people are exposed to high concentrations. Brisbane Lord Mayor Campbell Newman revealed this last night. Premier Anna Bligh however denies that there is such a risk. She has assured that the incinerator is safe and there have been no problems for the past twenty year.

8 Jun 2010

Antiemetic-regimen with fosaprepitant injection provides similar protection against CINV as oral EMEND

Merck announced today results from a new non-inferiority trial of an antiemetic regimen containing fosaprepitant dimeglumine administered as a single intravenous (IV) 150-mg dose in combination with a 5-HT3 antagonist and dexamethasone compared with a three-day regimen of aprepitant with a 5-HT3 antagonist and dexamethasone for the prevention of chemotherapy-induced nausea and vomiting (CINV) in patients receiving a first cycle of cisplatin-based chemotherapy.

4 Jun 2010

Entelos' T1D PhysioLab platform published in Clinical and Experimental Immunology

Entelos, Inc. has announced a publication in the peer-reviewed journal Clinical and Experimental Immunology describing the Type 1 Diabetes (T1D) PhysioLab® platform, an in silico solution for rapidly streamlining preclinical research through the evaluation of alternative scenarios for therapeutic strategies.

2 Jun 2010

Akela Pharma fourth-quarter consolidated net loss increases to $14.1M

Akela Pharma, Inc., a leader in the development of therapeutics for the treatment of pain, and the company's wholly owned subsidiary, PharmaForm, today announced its financial results for the three months and year ended December 31, 2009.

1 Jun 2010

Eating animals' meat hunted using lead ammunition can be dangerous for health: Study

Eating the meat of animals hunted using lead ammunition can be more dangerous for health than was previously thought, especially for children and people who consume large quantities. This is reflected in a study carried out by British and Spanish researchers that has been published by the journal PLos ONE.

31 May 2010

NSF International tests, certifies nutritional supplements to prevent unacceptable contaminants

Recent news coverage has consumers concerned about the alarming amount of contaminants, such as pesticides and heavy metals, being found in herbal supplements. NSF International, an independent, not-for-profit public health organization, helps ease these concerns by testing and certifying supplements to ensure they are free of undeclared substances and unacceptable contaminants.

29 May 2010

Study demonstrates protection against Ebola infection in nonhuman primates using RNAi

Scientists using tiny particles of genetic material to interfere in the replication process of the deadly Ebola virus have successfully prevented monkeys exposed to that virus from dying of hemorrhagic fever. The proof-of-concept study, published in this week's issue of The Lancet, suggests that such protection also should be possible in humans.

29 May 2010

Study measures effects of BPA on male reproductive system

Increasing Bisphenol-A levels in urine are associated with worsening male sexual function, according to a Kaiser Permanente study appearing online in the Journal of Andrology.

28 May 2010

Hamilton Thorne announces vendor partnership agreement with Leica Microsystems

Hamilton Thorne Ltd., a leading provider of advanced laser systems and instruments for the stem cell research and fertility clinic markets, today announces a vendor partnership agreement with Leica Microsystems GmbH of Wetzlar, Germany, a leading global designer and producer of innovative high-tech precision optics systems for the analysis of microstructures.

28 May 2010

Scientists develop inexpensive method for determining chemicals that may cause skin allergies

Scientists are reporting development of a fast, simple, inexpensive method for determining whether chemicals in consumer products and workplaces may cause skin allergies in people -- a method that does not involve use of animals. Their study appears in ACS' Chemical Research in Toxicology, a monthly journal.

27 May 2010

Toxicology News and Research

Latest Toxicology News and Research

Research identifies early biomarker for insulin resistance, glucose intolerance in nondiabetic population

Smokeless tobacco affects normal function of CYP-450 family of enzymes: Report

Hamilton Thorne announces launch of Staccato multi-pulse laser system at 8th ISSCR Annual Meeting

CDI, Promega enter collaboration for toxicity testing in drug discovery process

Asterand subsidiary BioSeek signs agreement with Amylin

Helix BioPharma third-quarter revenues increase 20.6%

CPL Biologicals completes construction of vaccine facility in Dholka, India

MicroConstants adds second Waters Xevo TQ MS system

Repligen's fiscal 2010 total revenue decreases to $20,971,000

Lytix Biopharma, KAEL-GemVax granted approval for GV1001/LTX-315 combination cancer therapy study

Waste incinerator spewing chemical waste: Says worried Brisbane Lord Mayor

Antiemetic-regimen with fosaprepitant injection provides similar protection against CINV as oral EMEND

Entelos' T1D PhysioLab platform published in Clinical and Experimental Immunology

Akela Pharma fourth-quarter consolidated net loss increases to $14.1M

Eating animals' meat hunted using lead ammunition can be dangerous for health: Study

NSF International tests, certifies nutritional supplements to prevent unacceptable contaminants

Study demonstrates protection against Ebola infection in nonhuman primates using RNAi

Study measures effects of BPA on male reproductive system

Hamilton Thorne announces vendor partnership agreement with Leica Microsystems

Scientists develop inexpensive method for determining chemicals that may cause skin allergies

Forensics and toxicology - Industry Focus eBook eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Toxicology News and Research

Latest Toxicology News and Research

Forensics and toxicology - Industry Focus eBook eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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