Vaccine News and Research

Latest Vaccine News and Research

SARS-CoV-2 B.1.617 mutations L452 and E484Q do not work together to evade antibodies

A short report recently published in the Journal of Infectious Diseases demonstrates how spike mutations L452R and E484Q found in the variant B.1.617.1 of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) each confer modestly diminished sensitivity to Pfizer-BioNTech (BNT162b2) mRNA vaccine-elicited antibodies – with combined mutations having a similar impact as either one of them alone.

19 Jul 2021

Pfizer-BioNTech and Moderna COVID-19 vaccines establish recall responses to reinfection

Researchers in the United States have conducted a study showing that the coronavirus disease 2019 (COVID-19) vaccines developed by Pfizer-BioNTech and Moderna generate a coordinated adaptive immune response that is capable of eliciting recall responses to future infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Jul 2021

How do immunocompromised patients respond to COVID-19 vaccines?

The COVID-19 vaccines produce a boost in antibody activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, new research suggests vaccine responses aren’t all created equal. Their findings showed that immunocompromised patients, such as transplant recipients, with no prior exposure to SARS-CoV-2 produce little to no neutralizing antibodies.

18 Jul 2021

Evaluation of a synthetic DNA SARS-CoV-2 vaccine INO-4800 using a nonhuman primate model

A new study published in Vaccine assesses the safety and efficacy of the synthetic DNA vaccine candidate INO-4800, delivered as a single or double dose regime.

18 Jul 2021

A drug candidate to prevent adverse reactions due to COVID-19 infection or vaccines

A new study describes the promising results of a new drug candidate in combating the illness caused by the binding of COVID-19-specific antibodies to infected cells.

18 Jul 2021

Researchers isolate human monoclonal antibodies that may neutralize several norovirus variants

Researchers at Vanderbilt University Medical Center and the Baylor College of Medicine in Houston, Texas, have taken a big step toward developing targeted treatments and vaccines against a family of viruses that attacks the gastrointestinal tract.

16 Jul 2021

Study provides insights into vaccine acceptance and hesitancy in low- and-middle income countries

New research published in Nature Medicine reveals willingness to get a COVID-19 vaccine was considerably higher in developing countries (80% of respondents) than in the United States (65%) and Russia (30%).

16 Jul 2021

Messenger RNA vaccines against COVID-19 not found in breast milk

Messenger RNA vaccines against COVID-19 were not detected in human milk, according to a small study by UC San Francisco, providing early evidence that the vaccine mRNA is not transferred to the infant.

16 Jul 2021

India's Mission Indradhanush improves vaccination outcomes for children

Researchers at CDDEP recently published 'Improving vaccination coverage and timeliness through periodic intensification of routine immunization: evidence from Mission Indradhanush' where they evaluated the performance of India's Mission Indradhanush (MI) child vaccination campaign -- a periodic intensification of the routine immunization program.

16 Jul 2021

Moderna SARS-CoV-2 vaccine highly effective against alpha and beta variants

The Moderna SARS-CoV-2 vaccine was widely distributed and had a reported efficacy in clinical trials of 94.1% against the wildtype SARS-CoV-2 following the second dose administration. Therefore, Chemaitelly et al. used this as an opportunity to measure the vaccine's efficacy against these variants as reported in a recent Nature Medicine paper, finding that the vaccine has good efficacy in all aspects.

16 Jul 2021

Mixing COVID vaccines generates a comparable immune response

The validity and safety of mixing first and second doses of different types are explored in a paper recently uploaded to the preprint server medRxiv* by Rose et al. (July 13th, 2021), finding that robust antibody response is induced, comparable to, and perhaps even exceed that generated by homologous dosing.

16 Jul 2021

Water-soluble vitamin E compounds directly inhibit SARS-CoV-2 replication and synergize with remdesivir

Researchers in the United States have shown that water-soluble derivatives of vitamin E (α-tocopherol) exhibit potent antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

15 Jul 2021

COVID-19 vaccine candidate that can be produced in yeast proves effective in macaques

Researchers in the United States have designed a modular protein subunit vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that elicited a strong immune response in macaques and prevented the animals from developing coronavirus disease 2019 (COVID-19).

15 Jul 2021

COVID-19 researchers review 184 drug repurposing candidates

New research describes the use of integrative bioinformatics analyses of transcriptomic profiles for COVID-19 therapeutics.

15 Jul 2021

23 million children missed out on basic vaccines in 2020 due to COVID-19, new data shows

23 million children missed out on basic vaccines through routine immunization services in 2020 – 3.7 million more than in 2019 - according to official data published today by WHO and UNICEF.

15 Jul 2021

Should we be concerned about the SARS-CoV-2 Lambda variant?

As the coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), wreaks havoc across the globe, the efficacy of available vaccines is being threatened by emerging variants.

15 Jul 2021

COVID-19 vaccine offers lesser, delayed protection against infection in people with cirrhosis

A study shows for the first time that people with cirrhosis who receive mRNA COVID-19 vaccination gain important protection against more serious outcomes like hospitalization and death. At the same time, however, the vaccines offer less protection against SARS-CoV-2 infection and take longer to take effect in this population.

14 Jul 2021

“Herd immunity” not responsible for Sweden’s control of COVID-19, say researchers

Researchers in Sweden have challenged the interpretation that variable non-pharmaceutical interventions (NPIs) and “herd immunity” protection are responsible for the rise and fall of coronavirus disease 2019 (COVID-19) epidemic waves in hard-hit locations where authorities have not enforced strict NPIs.

14 Jul 2021

Virtual schooling exposes the lack of digital resources among Black families

A new study from the University of Missouri found the unanticipated transitions to virtual schooling due to COVID-19 exposed the lack of digital resources among Black families in the United States, including access to Wi-Fi and technological savviness.

14 Jul 2021

New OMV-based COVID-19 vaccine candidate proves effective in mice

Researchers in Italy have demonstrated the efficacy of using modified outer membrane vesicles (OMVs) as a vaccine to protect against coronavirus disease 2019 (COVID-19) in an animal model.

14 Jul 2021

Vaccine News and Research

Latest Vaccine News and Research

SARS-CoV-2 B.1.617 mutations L452 and E484Q do not work together to evade antibodies

Pfizer-BioNTech and Moderna COVID-19 vaccines establish recall responses to reinfection

How do immunocompromised patients respond to COVID-19 vaccines?

Evaluation of a synthetic DNA SARS-CoV-2 vaccine INO-4800 using a nonhuman primate model

A drug candidate to prevent adverse reactions due to COVID-19 infection or vaccines

Researchers isolate human monoclonal antibodies that may neutralize several norovirus variants

Study provides insights into vaccine acceptance and hesitancy in low- and-middle income countries

Messenger RNA vaccines against COVID-19 not found in breast milk

India's Mission Indradhanush improves vaccination outcomes for children

Moderna SARS-CoV-2 vaccine highly effective against alpha and beta variants

Mixing COVID vaccines generates a comparable immune response

Water-soluble vitamin E compounds directly inhibit SARS-CoV-2 replication and synergize with remdesivir

COVID-19 vaccine candidate that can be produced in yeast proves effective in macaques

COVID-19 researchers review 184 drug repurposing candidates

23 million children missed out on basic vaccines in 2020 due to COVID-19, new data shows

Should we be concerned about the SARS-CoV-2 Lambda variant?

COVID-19 vaccine offers lesser, delayed protection against infection in people with cirrhosis

“Herd immunity” not responsible for Sweden’s control of COVID-19, say researchers

Virtual schooling exposes the lack of digital resources among Black families

New OMV-based COVID-19 vaccine candidate proves effective in mice

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Vaccine News and Research

Latest Vaccine News and Research

Event guide: 3rd mRNA Process Development & Manufacturing Europe eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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